Protein Alignment CG31954 and PRSS53

DIOPT Version :10

• Sequence 1: NP_722915.1
• Gene: CG31954 / 33572
• FlyBaseID: FBgn0051954
• Length: 277
• Species: Drosophila melanogaster
• Sequence 2: XP_011544118.1
• Gene: PRSS53 / 339105
• HGNCID: 34407
• Length: 623
• Species: Homo sapiens
• Alignment Length: 329
• Identity: 79/329 - (24%)
• Similarity: 140/329 - (42%)
• Gaps: 90/329 - (27%)

  Fly    14 LLVLAGVCLIPQPVK-RQRSLEDVIKNPWKLSPRLDGRIVGGHRINITDAPHQVSL-QTSSHICG 76
            :|::||..::.:.:: .||:...  :.|....|: :|..|.|      :.|.|.|: :..:|||.
Human     8 VLLIAGATVLMEGLQAAQRACGQ--RGPGPPKPQ-EGNTVPG------EWPWQASVRRQGAHICS 63

  Fly    77 GSIISEEWILTAAHCTYGKTADRL---KVRLGTSEFARSG-----QLLRVQKIVQHAQFNYTNVD 133
            ||::::.|:||||||.....|..|   .|.||:.:  |.|     :.:.|..:.....:|:.:..
Human    64 GSLVADTWVLTAAHCFEKAAATELNSWSVVLGSLQ--REGLSPGAEEVGVAALQLPRAYNHYSQG 126

  Fly   134 YDFSLLQLAHPIKFDETKKAVKLPESQMKYMDGEACFVSGWGNTQNLLESREW------------ 186
            .|.:|||||||    .|...:.||:...::..|.:|:.:||  .|:..:.:.|
Human   127 SDLALLQLAHP----TTHTPLCLPQPAHRFPFGASCWATGW--DQDTSDGKCWPRLKLGEALCLP 185

  Fly   187 -----------------------------------LRQVEVPLVNQELCSEKYKQYGGVTER--- 213
                                               ||.:.:.|:::..|:..|.|   :.:|
Human   186 SVTVSAPNCPGFQSPLLPRSQTLAPAPSLSPAPGTLRNLRLRLISRPTCNCIYNQ---LHQRHLS 247

  Fly   214 ------MICAGFLEGGKDACQGDSGGPM--VSESGELV--GVVSWGYGCAKPDYPGVYSRVSFAR 268
                  |:|.|...|.:..||||||||:  :...|..|  |::|:...||:.|.|.:.:..:...
Human   248 NPARPGMLCGGPQPGVQGPCQGDSGGPVLCLEPDGHWVQAGIISFASSCAQEDAPVLLTNTAAHS 312

  Fly   269 DWIK 272
            .|::
Human   313 SWLQ 316

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31954	NP_722915.1	Tryp_SPc	51..274	CDD:238113	71/291 (24%)
PRSS53	XP_011544118.1	Tryp_SPc	42..316	CDD:238113	71/290 (24%)
		Tryp_SPc	359..>512	CDD:473915