DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31954 and prss60.3

DIOPT Version :9

Sequence 1:	NP_722915.1	Gene:	CG31954 / 33572	FlyBaseID:	FBgn0051954	Length:	277	Species:	Drosophila melanogaster
Sequence 2:	XP_002662541.2	Gene:	prss60.3 / 335152	ZFINID:	ZDB-GENE-030131-7092	Length:	330	Species:	Danio rerio

Alignment Length:	279	Identity:	106/279 - (37%)
Similarity:	146/279 - (52%)	Gaps:	35/279 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LQCSLLVLAGVCLIPQPVKRQRSLEDVIKNPWKLSPRLDGRIVGGHRINITDAPHQVSLQT---S 71
            |.|:.|.|. :|:       :.||..:  |....:| |:.|||||...:....|.||||.:   .
Zfish     6 LTCATLTLL-ICV-------KGSLSQL--NVCGQAP-LNTRIVGGVNASPGSWPWQVSLHSPKYG 59

  Fly    72 SHICGGSIISEEWILTAAHCTYGKTADRLKVRLGTS--------EFARSGQLLRVQKIVQHAQFN 128
            .|.||||:||.||:||||||..|.:...|.|.||..        |.:|:     |.|...|:.:|
Zfish    60 GHFCGGSLISSEWVLTAAHCLSGVSETTLVVYLGRRTQQGINIYETSRN-----VAKSFVHSSYN 119

  Fly   129 YTNVDYDFSLLQLAHPIKFDETKKAVKLPESQMKYMDGEACFVSGWGNTQ---NLLESREWLRQV 190
            ....|.|.:||:|:..:.|....:.|.|......|..|.:.:::|||:.|   | |.:...|::.
Zfish   120 SNTNDNDIALLRLSSAVTFTNYIRPVCLAAQNSVYSAGTSSWITGWGDIQAGVN-LPAPGILQET 183

  Fly   191 EVPLVNQELCSEKYKQYGGVTERMICAGFLEGGKDACQGDSGGPMVSESGEL---VGVVSWGYGC 252
            .:|:|..:.|:..... |.||..|||||..:||||.||||||||||:....:   .|:.||||||
Zfish   184 MIPVVANDRCNALLGS-GTVTNNMICAGLTQGGKDTCQGDSGGPMVTRLCTVWVQAGITSWGYGC 247

  Fly   253 AKPDYPGVYSRVSFARDWI 271
            |.|:.||||:|||..:.||
Zfish   248 ADPNSPGVYTRVSQYQSWI 266

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31954	NP_722915.1	Tryp_SPc	50..271	CDD:214473	94/237 (40%)
CG31954	NP_722915.1	Tryp_SPc	51..274	CDD:238113	95/238 (40%)
prss60.3	XP_002662541.2	Tryp_SPc	36..269	CDD:238113	95/238 (40%)
prss60.3	XP_002662541.2	Somatomedin_B	294..328	CDD:321959
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900