DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31954 and Prss53

DIOPT Version :9

Sequence 1:	NP_722915.1	Gene:	CG31954 / 33572	FlyBaseID:	FBgn0051954	Length:	277	Species:	Drosophila melanogaster
Sequence 2:	NP_001074737.1	Gene:	Prss53 / 330657	MGIID:	2652890	Length:	552	Species:	Mus musculus

Alignment Length:	284	Identity:	76/284 - (26%)
Similarity:	134/284 - (47%)	Gaps:	44/284 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 LLVLAGVCLIPQPVKRQRSLEDVIKNPWKLSPRLDGRIVGGHRINITDAPHQVSLQTSS-HICGG 77
            ||::..|.:|......||:...  :.|....|: :|..:.|      :.|.|.|::... |||.|
Mouse     9 LLIVGAVVVIEGLQAAQRACGQ--RGPGPPEPQ-EGNTLPG------EWPWQASVRRQGVHICSG 64

  Fly    78 SIISEEWILTAAHCTYGKTA----DRLKVRLGTSEFARSGQLLRVQKIVQHA-----QFNYTNVD 133
            |::::.|:|||||| :.|.|    ....|.||:  ..:.||....:::...|     .:|:.:..
Mouse    65 SLVADTWVLTAAHC-FEKMATAELSSWSVVLGS--LKQEGQSPGAEEVGVAALQLPKAYNHYSQG 126

  Fly   134 YDFSLLQLAHPIKFDETKKAVKLPESQMKYMDGEACFVSGWGNTQNLLESREWLRQVEVPLVNQE 198
            .|.:||||.||    ..:..:.||:....:..|.:|:.:||  .||..:....||.:.:.|:::.
Mouse   127 SDLALLQLTHP----TVQTTLCLPQPTYHFPFGASCWATGW--DQNTSDVSRTLRNLRLRLISRP 185

  Fly   199 LCSEKYKQYGGVTER---------MICAGFLEGGKDACQGDSGGPMVSESGE----LVGVVSWGY 250
            .|:..|.:   :.:|         |:|.|...|.:..||||||||::....:    .||::|:..
Mouse   186 TCNCLYNR---LHQRLLSNPARPGMLCGGAQPGEQGPCQGDSGGPVMCREPDGHWVQVGIISFTS 247

  Fly   251 GCAKPDYPGVYSRVSFARDWIKEH 274
            .||:.|.|.:.:.::....|::.|
Mouse   248 KCAQEDTPVLLTDMAVHSSWLQAH 271

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31954	NP_722915.1	Tryp_SPc	50..271	CDD:214473	65/243 (27%)
CG31954	NP_722915.1	Tryp_SPc	51..274	CDD:238113	66/245 (27%)
Prss53	NP_001074737.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	27..46		3/21 (14%)
		Tryp_SPc	45..271	CDD:238113	66/243 (27%)
		Tryp_SPc	311..522	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839483
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24276
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.940