Protein Alignment CG31954 and HPN

DIOPT Version :10

• Sequence 1: NP_722915.1
• Gene: CG31954 / 33572
• FlyBaseID: FBgn0051954
• Length: 277
• Species: Drosophila melanogaster
• Sequence 2: NP_002142.1
• Gene: HPN / 3249
• HGNCID: 5155
• Length: 417
• Species: Homo sapiens
• Alignment Length: 284
• Identity: 106/284 - (37%)
• Similarity: 153/284 - (53%)
• Gaps: 28/284 - (9%)

  Fly    14 LLVLAGVCLIPQPVKRQRSLEDVIKNPWKLSPRLDGRIVGGHRINITDAPHQVSLQ-TSSHICGG 77
            ||.:..||..|    |.|.|..:.::..:....:| |||||...::...|.||||: ..:|:|||
Human   131 LLEVISVCDCP----RGRFLAAICQDCGRRKLPVD-RIVGGRDTSLGRWPWQVSLRYDGAHLCGG 190

  Fly    78 SIISEEWILTAAHC--TYGKTADRLKVRLG-TSEFARSGQLLRVQKIVQHAQF------NYTNVD 133
            |::|.:|:||||||  ...:...|.:|..| .::.:..|..|.||.:|.|..:      |.....
Human   191 SLLSGDWVLTAAHCFPERNRVLSRWRVFAGAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENS 255

  Fly   134 YDFSLLQLAHPIKFDETKKAVKLPESQMKYMDGEACFVSGWGNTQNLLESREWLRQVEVPLVNQE 198
            .|.:|:.|:.|:...|..:.|.||.:....:||:.|.|:||||||...:....|::..||:::.:
Human   256 NDIALVHLSSPLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISND 320

  Fly   199 LCSEKYKQYGG-VTERMICAGFLEGGKDACQGDSGGPMVSESG-------ELVGVVSWGYGCAKP 255
            :|:.. ..||. :..:|.|||:.|||.||||||||||.|.|..       .|.|:||||.|||..
Human   321 VCNGA-DFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALA 384

  Fly   256 DYPGVYSRVSFARDW----IKEHS 275
            ..||||::||..|:|    ||.||
Human   385 QKPGVYTKVSDFREWIFQAIKTHS 408

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31954	NP_722915.1	Tryp_SPc	51..274	CDD:238113	94/244 (39%)
HPN	NP_002142.1	Hepsin-SRCR	51..159	CDD:462736	8/31 (26%)
		Tryp_SPc	163..400	CDD:238113	91/237 (38%)