DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31954 and Klk8

DIOPT Version :9

Sequence 1:	NP_722915.1	Gene:	CG31954 / 33572	FlyBaseID:	FBgn0051954	Length:	277	Species:	Drosophila melanogaster
Sequence 2:	NP_001100979.1	Gene:	Klk8 / 308565	RGDID:	1305998	Length:	260	Species:	Rattus norvegicus

Alignment Length:	251	Identity:	85/251 - (33%)
Similarity:	127/251 - (50%)	Gaps:	20/251 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 VIKNPWKLSPRLDG-RIVGGHRINITDAPHQVSL-QTSSHICGGSIISEEWILTAAHCTYGKTAD 98
            ::...|....|..| :|:.|........|.|.:| |....:|||.::.:.|:||||||    ..|
  Rat    17 LLMGAWAGLTRAQGSKILEGQECKPHSQPWQTALFQGERLVCGGVLVGDRWVLTAAHC----KKD 77

  Fly    99 RLKVRLGTSEFARSG---QLLRVQKIVQHAQFNYTNVD---YDFSLLQLAHPIKFDETKKAVKLP 157
            :..||||.....:..   |.::|.:.:||..||.:|.:   :|..|::|.:.....:..|.::|.
  Rat    78 KYSVRLGDHSLQKRDEPEQEIQVARSIQHPCFNSSNPEDHSHDIMLIRLQNSANLGDKVKPIELA 142

  Fly   158 ESQMKYMDGEACFVSGWGNTQNLLES-REWLRQVEVPLVNQELCSEKYKQYGGVTERMICAGFLE 221
            ....|.  |:.|.:||||...:..|: ...|...||.:.:|..|...|.  |.:||.|:||| ..
  Rat   143 NLCPKV--GQKCIISGWGTVTSPQENFPNTLNCAEVKIYSQNKCERAYP--GKITEGMVCAG-SS 202

  Fly   222 GGKDACQGDSGGPMVSESGELVGVVSWGYG-CAKPDYPGVYSRVSFARDWIKEHSG 276
            .|.|.||||||||:|. :|.|.|:.|||.. |.||:.||||:::....:|||:..|
  Rat   203 NGADTCQGDSGGPLVC-NGVLQGITSWGSDPCGKPEKPGVYTKICRYTNWIKKTMG 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31954	NP_722915.1	Tryp_SPc	50..271	CDD:214473	78/229 (34%)
CG31954	NP_722915.1	Tryp_SPc	51..274	CDD:238113	81/231 (35%)
Klk8	NP_001100979.1	Tryp_SPc	32..252	CDD:214473	78/229 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8983
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X21
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910