DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31954 and Klk11

DIOPT Version :9

Sequence 1:	NP_722915.1	Gene:	CG31954 / 33572	FlyBaseID:	FBgn0051954	Length:	277	Species:	Drosophila melanogaster
Sequence 2:	NP_001099722.1	Gene:	Klk11 / 292849	RGDID:	1308690	Length:	279	Species:	Rattus norvegicus

Alignment Length:	296	Identity:	92/296 - (31%)
Similarity:	132/296 - (44%)	Gaps:	71/296 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 VKRQRSLEDVIKNPWKLS--PRLDG----------------------------RIVGGHRINITD 61
            ::|.|.|    |:.||||  ||..|                            ||:.|:......
  Rat     1 MRRPRRL----KSDWKLSTEPREPGARPALLQAMMILRFIALALVTGHVGGETRIIKGYECRPHS 61

  Fly    62 APHQVSL-QTSSHICGGSIISEEWILTAAHC------------TYGKTADRLKVRLGTSEFARSG 113
            .|.||:| |.:..:||.::|:.:|:||||||            ...||....:.|:.|..|
  Rat    62 QPWQVALFQKTRLLCGATLIAPKWLLTAAHCRKPHYVILLGEHNLEKTDGCEQRRMATESF---- 122

  Fly   114 QLLRVQKIVQHAQFNYT--NVDY--DFSLLQLAHPIKFDETKKAVKLPESQMKYMDGEACFVSGW 174
                     .|..||.:  |.|:  |..|::::.|...  |:....|..|.:....|.:|.:|||
  Rat   123 ---------PHPGFNNSLPNKDHRNDIMLVKMSSPAFI--TRAVRPLTLSSLCVTAGTSCLISGW 176

  Fly   175 GNTQN-LLESREWLRQVEVPLVNQELCSEKYKQYGGVTERMICAGFLEGGKDACQGDSGGPMVSE 238
            |.|.: .|.....||...|.::..:.|...|.  |.:|:.|:||...:.|||:||||||||:|.
  Rat   177 GTTSSPQLRLPHSLRCANVSIIGHKECERAYP--GNITDTMLCASVRKEGKDSCQGDSGGPLVC- 238

  Fly   239 SGELVGVVSWGYG-CAKPDYPGVYSRVSFARDWIKE 273
            :|.|.|::|||.. ||....||||::|....|||.|
  Rat   239 NGSLQGIISWGQDPCAVTRKPGVYTKVCKYFDWIHE 274

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31954	NP_722915.1	Tryp_SPc	50..271	CDD:214473	78/239 (33%)
CG31954	NP_722915.1	Tryp_SPc	51..274	CDD:238113	80/242 (33%)
Klk11	NP_001099722.1	Tryp_SPc	50..272	CDD:214473	78/239 (33%)
Klk11	NP_001099722.1	Tryp_SPc	51..275	CDD:238113	80/242 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469244at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8983
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X21
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.920