DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31954 and Prss2

DIOPT Version :9

Sequence 1:	NP_722915.1	Gene:	CG31954 / 33572	FlyBaseID:	FBgn0051954	Length:	277	Species:	Drosophila melanogaster
Sequence 2:	NP_033456.1	Gene:	Prss2 / 22072	MGIID:	102759	Length:	246	Species:	Mus musculus

Alignment Length:	230	Identity:	101/230 - (43%)
Similarity:	143/230 - (62%)	Gaps:	15/230 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 DGRIVGGHRINITDAPHQVSLQTSSHICGGSIISEEWILTAAHC-TYGKTADRLKVRLG---TSE 108
            |.:||||:....:..|:||||....|.||||:|:::|:::|||| .|     |::||||   .:.
Mouse    21 DDKIVGGYTCRESSVPYQVSLNAGYHFCGGSLINDQWVVSAAHCYKY-----RIQVRLGEHNINV 80

  Fly   109 FARSGQLLRVQKIVQHAQFNYTNVDYDFSLLQLAHPIKFDETKKAVKLPESQMKYMDGEACFVSG 173
            ...:.|.:...||::|..:|...:|.|..|::||.|:..:....:|.||.|...  .|..|.:||
Mouse    81 LEGNEQFVDSAKIIRHPNYNSWTLDNDIMLIKLASPVTLNARVASVPLPSSCAP--AGTQCLISG 143

  Fly   174 WGNT-QNLLESREWLRQVEVPLVNQELCSEKYKQYGGVTERMICAGFLEGGKDACQGDSGGPMVS 237
            |||| .|.:.:.:.|:.|:.|::.|..|...|.  |.:|..|||.||||||||:||||||||:|.
Mouse   144 WGNTLSNGVNNPDLLQCVDAPVLPQADCEASYP--GDITNNMICVGFLEGGKDSCQGDSGGPVVC 206

  Fly   238 ESGELVGVVSWGYGCAKPDYPGVYSRVSFARDWIK 272
             :|||.|:||||||||:||.||||::|....|||:
Mouse   207 -NGELQGIVSWGYGCAQPDAPGVYTKVCNYVDWIQ 240

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31954	NP_722915.1	Tryp_SPc	50..271	CDD:214473	98/225 (44%)
CG31954	NP_722915.1	Tryp_SPc	51..274	CDD:238113	100/227 (44%)
Prss2	NP_033456.1	Tryp_SPc	23..239	CDD:214473	98/225 (44%)
Prss2	NP_033456.1	Tryp_SPc	24..242	CDD:238113	100/227 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	187	1.000	Domainoid score	I3329
eggNOG	1	0.900	-	-		E33208_3BBP0
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	191	1.000	Inparanoid score	I3860
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469244at33208
OrthoFinder	1	1.000	-	-		FOG0000102
OrthoInspector	1	1.000	-	-		otm42678
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5191
SonicParanoid	1	1.000	-	-		X21
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	10.800