Protein Alignment CG31954 and F12

DIOPT Version :10

• Sequence 1: NP_722915.1
• Gene: CG31954 / 33572
• FlyBaseID: FBgn0051954
• Length: 277
• Species: Drosophila melanogaster
• Sequence 2: NP_000496.2
• Gene: F12 / 2161
• HGNCID: 3530
• Length: 615
• Species: Homo sapiens
• Alignment Length: 273
• Identity: 91/273 - (33%)
• Similarity: 132/273 - (48%)
• Gaps: 24/273 - (8%)

  Fly    26 PVKRQRSLEDVIKNPWKLSPRLD------GRIVGGHRINITDA-PHQVSLQTSSHICGGSIISEE 83
            |.||::........|.....||.      .|:||| .:.:..| |:..:|......|.||:|:..
Human   342 PAKREQPPSLTRNGPLSCGQRLRKSLSSMTRVVGG-LVALRGAHPYIAALYWGHSFCAGSLIAPC 405

  Fly    84 WILTAAHCTYGKTA-DRLKVRLGTSEFARS---GQLLRVQKIVQHAQFNYTNVDYDFSLLQLAHP 144
            |:||||||...:.| :.|.|.||......|   .|.|.|:....|..|:..:..:|.:||:|...
Human   406 WVLTAAHCLQDRPAPEDLTVVLGQERRNHSCEPCQTLAVRSYRLHEAFSPVSYQHDLALLRLQED 470

  Fly   145 IK-----FDETKKAVKLPESQMKYMDGEACFVSGWGNT-QNLLESREWLRQVEVPLVNQELCSEK 203
            ..     .....:.|.||....:..:...|.|:|||:. :...|...:|::.:||.::.|.||..
Human   471 ADGSCALLSPYVQPVCLPSGAARPSETTLCQVAGWGHQFEGAEEYASFLQEAQVPFLSLERCSAP 535

  Fly   204 YKQYGGVTERMICAGFLEGGKDACQGDSGGPMVSESG------ELVGVVSWGYGCAKPDYPGVYS 262
            ......:...|:||||||||.||||||||||:|.|..      .|.|::|||.||...:.||||:
Human   536 DVHGSSILPGMLCAGFLEGGTDACQGDSGGPLVCEDQAAERRLTLQGIISWGSGCGDRNKPGVYT 600

  Fly   263 RVSFARDWIKEHS 275
            .|::...||:||:
Human   601 DVAYYLAWIREHT 613

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31954	NP_722915.1	Tryp_SPc	51..274	CDD:238113	82/239 (34%)
F12	NP_000496.2	FN2	41..88	CDD:128373
		EGF_CA	96..131	CDD:238011
		FN1	133..173	CDD:238018
		EGF	178..206	CDD:394967
		Kringle	217..295	CDD:395005
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	298..359		4/16 (25%)
		Tryp_SPc	373..612	CDD:238113	82/239 (34%)