Protein Alignment CG31954 and F10

DIOPT Version :10

• Sequence 1: NP_722915.1
• Gene: CG31954 / 33572
• FlyBaseID: FBgn0051954
• Length: 277
• Species: Drosophila melanogaster
• Sequence 2: NP_000495.1
• Gene: F10 / 2159
• HGNCID: 3528
• Length: 488
• Species: Homo sapiens
• Alignment Length: 261
• Identity: 91/261 - (34%)
• Similarity: 133/261 - (50%)
• Gaps: 31/261 - (11%)

  Fly    35 DVIKNPWKLSPRLD-------------GRIVGGHRINITDAPHQVSL--QTSSHICGGSIISEEW 84
            |..:||:.|   ||             .|||||......:.|.|..|  :.:...|||:|:||.:
Human   209 DPTENPFDL---LDFNQTQPERGDNNLTRIVGGQECKDGECPWQALLINEENEGFCGGTILSEFY 270

  Fly    85 ILTAAHCTYGKTADRLKVRLG--TSEFARSGQLL-RVQKIVQHAQFNYTNVDYDFSLLQLAHPIK 146
            |||||||.|  .|.|.|||:|  .:|....|:.: .|:.:::|.:|.....|:|.::|:|..||.
Human   271 ILTAAHCLY--QAKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPIT 333

  Fly   147 FDETKKAVKLPE---SQMKYMDGEACFVSGWGNTQNLLESREWLRQVEVPLVNQELCSEKYKQYG 208
            |........|||   ::...|..:...|||:|.|.........|:.:|||.|::..|  |.....
Human   334 FRMNVAPACLPERDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSC--KLSSSF 396

  Fly   209 GVTERMICAGFLEGGKDACQGDSGGPMVSESGE---LVGVVSWGYGCAKPDYPGVYSRVSFARDW 270
            .:|:.|.|||:....:||||||||||.|:...:   :.|:||||.|||:....|:|::|:....|
Human   397 IITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKW 461

  Fly   271 I 271
            |
Human   462 I 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31954	NP_722915.1	Tryp_SPc	51..274	CDD:238113	84/232 (36%)
F10	NP_000495.1	GLA	25..85	CDD:214503
		EGF_CA	86..122	CDD:238011
		FXa_inhibition	129..164	CDD:464251
		O-glycosylated at one site	183..203
		Tryp_SPc	235..464	CDD:238113	84/232 (36%)
		O-glycosylated at one site	476..485