Protein Alignment CG31954 and KLK8

DIOPT Version :10

• Sequence 1: NP_722915.1
• Gene: CG31954 / 33572
• FlyBaseID: FBgn0051954
• Length: 277
• Species: Drosophila melanogaster
• Sequence 2: NP_653088.1
• Gene: KLK8 / 11202
• HGNCID: 6369
• Length: 305
• Species: Homo sapiens
• Alignment Length: 263
• Identity: 86/263 - (32%)
• Similarity: 125/263 - (47%)
• Gaps: 33/263 - (12%)

  Fly    23 IPQPVKRQRSLEDVIKNPWKLSPRLDGRIVGGHRINITDAPHQVSL-QTSSHICGGSIISEEWIL 86
            :|......|:.||              :::|||.......|.|.:| |....:|||.::...|:|
Human    64 LPPAAGHSRAQED--------------KVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVL 114

  Fly    87 TAAHCTYGKTADRLKVRLGTSEFARSG---QLLRVQKIVQHAQFNYTNVD---YDFSLLQLAHPI 145
            |||||...|    ..||||........   |.:.|.:.:.|..:|.::|:   :|..||||....
Human   115 TAAHCKKPK----YTVRLGDHSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQA 175

  Fly   146 KFDETKKAVKLPESQMKYMDGEACFVSGWGNTQNLLES-REWLRQVEVPLVNQELCSEKYKQYGG 209
            ......|.:.|.:...:  .|:.|.|||||...:..|: .:.|...||.:..|:.|.:.|.  |.
Human   176 SLGSKVKPISLADHCTQ--PGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYP--GQ 236

  Fly   210 VTERMICAGFLEGGKDACQGDSGGPMVSESGELVGVVSWGYG-CAKPDYPGVYSRVSFARDWIKE 273
            :|:.|:|||..:|. |.||||||||:|.: |.|.|:.|||.. |.:.|.||||:.:....||||:
Human   237 ITDGMVCAGSSKGA-DTCQGDSGGPLVCD-GALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKK 299

  Fly   274 HSG 276
            ..|
Human   300 IIG 302

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31954	NP_722915.1	Tryp_SPc	51..274	CDD:238113	81/231 (35%)
KLK8	NP_653088.1	Tryp_SPc	77..297	CDD:214473	78/229 (34%)