Protein Alignment tim and ATIM

DIOPT Version :10

• Sequence 1: NP_001334730.1
• Gene: tim / 33571
• FlyBaseID: FBgn0014396
• Length: 1421
• Species: Drosophila melanogaster
• Sequence 2: NP_001330129.1
• Gene: ATIM / 835368
• AraportID: AT5G52910
• Length: 1163
• Species: Arabidopsis thaliana
• Alignment Length: 1308
• Identity: 253/1308 - (19%)
• Similarity: 433/1308 - (33%)
• Gaps: 430/1308 - (32%)

  Fly    38 SSLGCLEGDT------YVVNPNALAILEEINYKLTYEDQTLRTFRRAIGFGQNVRSDLIPLLENA 96
            |.||..|.|.      |..:...|..|:::...|..:|...|...:.:.....|..||||::|:.
plant    23 SDLGLPEEDEDRRRIGYSKSEYCLDNLKDLLRFLRRDDPESREVFKQVCAWNIVSKDLIPIIEHY 87

  Fly    97 KDD--AVLESVIRILVNLTVPVECLFSVDVMYRTDVGRHTIFELNKLLYTSKEAFTEARSTKSVV 159
            :|:  .||.:| ::||.||:|:| ..|.|:..:.:           .|:..|.|.|.:.....:|
plant    88 QDEHNLVLNAV-KVLVFLTMPIE-PSSDDIPQQLE-----------YLWGLKSAITFSNIVAVIV 139

  Fly   160 EYMKHILES---------DPKLSPHKCDQINNCLLLLRNILHIPETHAHCVMPMM---QSMPHGI 212
            ..::..||:         |.||       :...|.|.||:|.|     |.|.|:.   :|..:.:
plant   140 SLLEAPLENLELDVFNEEDWKL-------VQLVLTLFRNLLAI-----HDVSPIQKAGESTCYFL 192

  Fly   213 SMQNTILWNLFIQSIDKLLLYLMTCPQRAFWGVTMVQLIALIYKDQHVSTLQKLLSLWFEASLSE 277
            |:::..|..|..:::..::|.:..         |:....:|:..|..:     ||.::....|
plant   193 SLRDQFLEVLSRENVMDIVLVITQ---------TIEGFNSLLRHDNLL-----LLEIYHYILL-- 241

  Fly   278 SSEDNESNTSPP------KQGSGDSSPMLTSDPTSDSSDNGSNGRGMGGGMREGTA----ATLQE 332
             .:|.|.....|      ||.|.||...|                     |:|...    |.|..
plant   242 -GQDMELVAKAPEKLDQGKQASVDSLKTL---------------------MKEEEVKRKLARLNN 284

  Fly   333 VSRKGQEYQNAMARVPAD------KPDGSEEASDMTGNDSEQPGSPEQSQPAGESMDDGDYEDQR 391
            ::::..::.....||..|      |...|...|.|.        .|:|.:.|.|.:
plant   285 MNQRHSQFGGTFTRVTMDGTKAVLKGIPSTTESTML--------KPQQGRGATEKI--------- 332

  Fly   392 HRQLNEHGEEDEDEDEVEEEEYLQLGPASEPLNLTQQPADKVNNTTNPTSSAPQGCLGNEPFKPP 456
               :.|||                      |:::|.   |||...
plant   333 ---VWEHG----------------------PMSVTN---DKVLKL-------------------- 349

  Fly   457 PPLPVRASTSAHAQMQKFNESSYASHVSAVKLGQKSPHAGQLQLTKGKCCPQKRECPSSQSELSD 521
                      .|..:.:|....|.                  .|.:..|...::|.||.|:  ||
plant   350 ----------LHDFINQFMSGGYN------------------VLMQSLCEDIEKEHPSIQN--SD 384

  Fly   522 CGYGTQVENQESISTSSNDDDGPQGKPQHQKPPCNTKPRNKPRTIMSPMDKKELRRKKLVKRSKS 586
            .....||  .:||::....      |.....|...|:..::..|          .:|..|..|||
plant   385 IVTFFQV--AQSITSFQFH------KSSASSPAIETEETSELTT----------NQKAGVNFSKS 431

  Fly   587 SLINMKGLVQHTPTDDDISNL---------------LKEFTVDF-LLKGYSYLVE------ELHM 629
            .:.        .|....|::.               ||| |.|| .|...|.||:      :|.:
plant   432 DIC--------APIAATINDRMFLLVISKWRCAFDGLKE-TKDFKFLSAASSLVKTMLCLLDLVI 487

  Fly   630 QLLSNAKVPIDTSHFFWLVTYFLKFAAQLELDMEHIDTILTYDVLSYLTYEGVSLCEQLELNA-- 692
            :||     |.|:...|.:                   .||.|.:....|.:|  :| |..||.
plant   488 KLL-----PEDSKEAFTV-------------------RILLYKLFYDQTDQG--MC-QFILNLVR 525

  Fly   693 -----RQEGSDLKPYLRRMHLVVTAIREFLQAIDTY----------------NK---VTHLNED- 732
                 :|..|:|...:..:|::| .:.|.||...|.                ||   |..|:|:
plant   526 SFDTHKQPKSELGDLVESIHIIV-GLMENLQGRGTLRVSKKSRKARKKKPKGNKEATVHKLSENH 589

  Fly   733 -------------------------------DKAHLRQLQLQISEMSDLRCLFVLLLRRFNPSIH 766
                                           :|.....|:.:..|...:.            |..
plant   590 PSTSNEASTAKSIPMVDSTVSTEDGPMDVPPNKPEASNLETETDETQQMH------------SPK 642

  Fly   767 SKQYLQDLVVTNHILLLILDSSAKLGGCQT------IRLSEHITQFATLEVMHYYGILLEDFNNN 825
            |...:.||...:.      |||.  |..||      .::|..|:.||:..::.....||:.:.:|
plant   643 SNNVVDDLSSGSD------DSSD--GEEQTATDEVDFKVSTFISAFASNSIIQNLCWLLKFYKSN 699

  Fly   826 GEFVNDCIFTMMHHIGGDLGQIGVLFQPIILKTYSRIWEADYEL-CDDWSDLIEY---VIHKFMN 886
            .:..|..:.:::..|..||....:|:|..:|.|:.:|.:..... |.|:.:::.:   ::...:.
plant   700 PKQTNHHVISILRRITEDLELAPMLYQLSLLITFHKILDEQKVCPCKDYENIVTFLTDLVRNMLK 764

  Fly   887 TPPKSPLTIPTTSLTEMTKEHNQEHTVCSWSQEEMDTLYWYYVQSKKNNDIVGKIVKLFSNNGNK 951
            .....||.......::..||       |.:...|.......:::.:..|.......:.|..:.:|
plant   765 KMKSQPLLFVEILFSKTRKE-------CHYINAEYMLHELGHLRKQMGNQEKFSGTEEFGTSSDK 822

  Fly   952 LKTRISIIQQLLQQDIITLLEYDDLMKFEDAEYQRTLLTTPTSATT------ESGIEIKECAYGK 1010
            .....|:...|...:...::.||...:.||.:........|:....      :..|:||: .|.:
plant   823 GWAHRSLADALGDDEADVVISYDQGFQNEDDDMVEDKSAGPSKRKRRLVLDGDMDIKIKD-LYDR 886

  Fly  1011 PSDDVQILLDLIIKEN--------KAQHLLWLQRILIECCFVKLTLRSGLKVPEGDHI-MEPVAY 1066
            ..||..  ...:|.||        .||....|:::.:|   .:..||.|    ..||: ...:|.
plant   887 YKDDKN--CSRLIAENLVPDGGISAAQVTNKLKQLGLE---TRKRLRRG----GTDHLDATSLAQ 942

  Fly  1067 HCICKQKSIPVVQWNNEQSTTM--LYQPF-------VLLLHKLGIQLPADAGSIFARIPDYWTPE 1122
            ....:::   |..::.||.|.:  ||:.|       .|:..:||.:            ..|.|.:
plant   943 PSNTRKR---VSSFSKEQETLIKELYKKFKDEKRCCYLIASELGSE------------NTYTTAQ 992

  Fly  1123 TMYGLAKKLG---PLDK-----LNLKFD-----ASELEDAT-ASSPSRYHHTGPRNSLSSVSSLD 1173
            ....| |:||   |..|     :.||.|     |.|.||.| .:..:|......:|...:.|..:
plant   993 VSRKL-KQLGLRLPRGKKSEAGMMLKDDHDDSSADESEDETLLAFKNRKSRKNQKNKQQTGSINE 1056

  Fly  1174 VDLGDTEE 1181
            :..|.:|:
plant  1057 ITPGGSED 1064

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tim	NP_001334730.1	TIMELESS	47..305	CDD:461444	63/283 (22%)
		TIMELESS_C	1018..1125	CDD:461529	25/124 (20%)
ATIM	NP_001330129.1	TIMELESS	38..297	CDD:461444	67/321 (21%)
		Csa3	868..>1009	CDD:442641	36/166 (22%)