Protein Alignment Thor and EIF4EBP1

DIOPT Version :9

• Sequence 1: NP_001285588.1
• Gene: Thor / 33569
• FlyBaseID: FBgn0261560
• Length: 117
• Species: Drosophila melanogaster
• Sequence 2: NP_004086.1
• Gene: EIF4EBP1 / 1978
• HGNCID: 3288
• Length: 118
• Species: Homo sapiens
• Alignment Length: 124
• Identity: 46/124 - (37%)
• Similarity: 71/124 - (57%)
• Gaps: 13/124 - (10%)

  Fly     1 MSASPTARQAITQALPMITRKVVISDPIQMPE-VYSSTPGGTLYSTTPGGTKLIYERAFMKNLRG 64
            ||...:..|..::|:| .||:||:.|.:|:|. .||:||||||:|||||||::||:|.|:...|.
Human     1 MSGGSSCSQTPSRAIP-ATRRVVLGDGVQLPPGDYSTTPGGTLFSTTPGGTRIIYDRKFLMECRN 64

  Fly    65 SPLSQTPPSNVPSCLLRGTPRTPFRKCVPVPTELIKQTKSLKIED------QEQFQLDL 117
            ||:::|||.::|:     .|..........|.|..:.......||      :.||::|:
Human    65 SPVTKTPPRDLPT-----IPGVTSPSSDEPPMEASQSHLRNSPEDKRAGGEESQFEMDI 118

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Thor	NP_001285588.1	eIF_4EBP	3..117	CDD:398880	43/120 (36%)
EIF4EBP1	NP_004086.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..20		6/19 (32%)
		eIF_4EBP	11..118	CDD:368450	42/112 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	25..48		14/22 (64%)
		YXXXXLphi motif. /evidence=ECO:0000250|UniProtKB:P70445	54..60		3/5 (60%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	64..118		13/58 (22%)
		TOS motif. /evidence=ECO:0000269|PubMed:12747827	114..118		1/3 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165148535
Domainoid	1	1.000	83	1.000	Domainoid score	I8345
eggNOG	1	0.900	-	-		E1_2CQCV
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	85	1.000	Inparanoid score	I5169
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1597535at2759
OrthoFinder	1	1.000	-	-		FOG0002674
OrthoInspector	1	1.000	-	-		otm42193
orthoMCL	1	0.900	-	-		OOG6_105200
Panther	1	1.100	-	-	LDO	PTHR12669
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5872
SonicParanoid	1	1.000	-	-		X1786
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.790