Protein Alignment Thor and EIF4EBP1

DIOPT Version :10

• Sequence 1: NP_477295.1
• Gene: Thor / 33569
• FlyBaseID: FBgn0261560
• Length: 117
• Species: Drosophila melanogaster
• Sequence 2: NP_004086.1
• Gene: EIF4EBP1 / 1978
• HGNCID: 3288
• Length: 118
• Species: Homo sapiens
• Alignment Length: 124
• Identity: 46/124 - (37%)
• Similarity: 71/124 - (57%)
• Gaps: 13/124 - (10%)

  Fly     1 MSASPTARQAITQALPMITRKVVISDPIQMPE-VYSSTPGGTLYSTTPGGTKLIYERAFMKNLRG 64
            ||...:..|..::|:| .||:||:.|.:|:|. .||:||||||:|||||||::||:|.|:...|.
Human     1 MSGGSSCSQTPSRAIP-ATRRVVLGDGVQLPPGDYSTTPGGTLFSTTPGGTRIIYDRKFLMECRN 64

  Fly    65 SPLSQTPPSNVPSCLLRGTPRTPFRKCVPVPTELIKQTKSLKIED------QEQFQLDL 117
            ||:::|||.::|:     .|..........|.|..:.......||      :.||::|:
Human    65 SPVTKTPPRDLPT-----IPGVTSPSSDEPPMEASQSHLRNSPEDKRAGGEESQFEMDI 118

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Thor	NP_477295.1	eIF_4EBP	9..117	CDD:461656	43/114 (38%)
EIF4EBP1	NP_004086.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..20		6/19 (32%)
		eIF_4EBP	9..118	CDD:461656	43/114 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	25..48		14/22 (64%)
		YXXXXLphi motif. /evidence=ECO:0000250|UniProtKB:P70445	54..60		3/5 (60%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	64..118		13/58 (22%)
		TOS motif. /evidence=ECO:0000269|PubMed:12747827, ECO:0000269|PubMed:24403073	114..118		1/3 (33%)