Protein Alignment Thor and Eif4ebp2

DIOPT Version :9

• Sequence 1: NP_001285588.1
• Gene: Thor / 33569
• FlyBaseID: FBgn0261560
• Length: 117
• Species: Drosophila melanogaster
• Sequence 2: NP_034254.1
• Gene: Eif4ebp2 / 13688
• MGIID: 109198
• Length: 120
• Species: Mus musculus
• Alignment Length: 131
• Identity: 49/131 - (37%)
• Similarity: 74/131 - (56%)
• Gaps: 25/131 - (19%)

  Fly     1 MSASPTARQAITQALPMITRKVVISDPIQMPEVYSSTPGGTLYSTTPGGTKLIYERAFMKNLRGS 65
            ||||.......:|:..:.||.|.|||..|:|:.|.:||||||:|||||||::||:|.|:.:.|.|
Mouse     1 MSASAGGSHQPSQSRAIPTRTVAISDAAQLPQDYCTTPGGTLFSTTPGGTRIIYDRKFLLDRRNS 65

  Fly    66 PLSQTPPSNVPSCLLRGTPRTPFRKCVPVPTELIKQTK--------------SLKIEDQEQFQLD 116
            |::||||.::|:  :.|         |..|..||:.:|              ...:.|:.||::|
Mouse    66 PMAQTPPCHLPN--IPG---------VTSPGALIEDSKVEVNNLNNLNNHDRKHAVGDEAQFEMD 119

  Fly   117 L 117
            :
Mouse   120 I 120

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Thor	NP_001285588.1	eIF_4EBP	3..117	CDD:398880	46/127 (36%)
Eif4ebp2	NP_034254.1	eIF_4EBP	13..120	CDD:368450	44/117 (38%)
		YXXXXLphi motif. /evidence=ECO:0000250|UniProtKB:Q13542	54..60		3/5 (60%)
		TOS motif. /evidence=ECO:0000269|PubMed:20347422	116..120		1/3 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167838645
Domainoid	1	1.000	82	1.000	Domainoid score	I8394
eggNOG	1	0.900	-	-		E1_2CQCV
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	86	1.000	Inparanoid score	I5145
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1597535at2759
OrthoFinder	1	1.000	-	-		FOG0002674
OrthoInspector	1	1.000	-	-		otm44244
orthoMCL	1	0.900	-	-		OOG6_105200
Panther	1	1.100	-	-	O	PTHR12669
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5872
SonicParanoid	1	1.000	-	-		X1786
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.790