Protein Alignment CG31776 and GALNT14

DIOPT Version :10

• Sequence 1: NP_722909.2
• Gene: CG31776 / 33568
• FlyBaseID: FBgn0051776
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: NP_001240755.1
• Gene: GALNT14 / 79623
• HGNCID: 22946
• Length: 557
• Species: Homo sapiens
• Alignment Length: 557
• Identity: 172/557 - (30%)
• Similarity: 264/557 - (47%)
• Gaps: 72/557 - (12%)

  Fly    90 PQQEAIKEWQDAIFFKEDSNRRGLGEQGRAVQLPNAKLNPDD------------------FQDFY 136
            |:.:..|.|  ::|||.      .|....|.|:|.:...|..                  .|:..
Human    37 PEVQTPKVW--SLFFKV------AGMSPWAPQVPVSPTPPYQRGHLPTGGHLAVCHFPCLLQEAQ 93

  Fly   137 AELSDRIPLNRSLPDTRPISCRKRKYLENLPNVTVIIAFHDEHLSVLLRSITSIINRSPVELLKQ 201
            ..|..::.|.        :.|....|..:||..::||.||:|..|.|||:|.|::||:|..|:::
Human    94 FHLQTQVFLQ--------VRCTLLVYCTDLPPTSIIITFHNEARSTLLRTIRSVLNRTPTHLIRE 150

  Fly   202 IVLVDDDSNLPELGQQLEEIVAQNFPKIIHILRLPERRGSIKARMEAIRVSSCQVLVFLDSHIEV 266
            |:||||.||.|:..:||.::     || :..||..||:|.:::|:....::....|.|||||.||
Human   151 IILVDDFSNDPDDCKQLIKL-----PK-VKCLRNNERQGLVRSRIRGADIAQGTTLTFLDSHCEV 209

  Fly   267 NTNWLPPLLEPIVINPHIVTRPILDAISRKTFAYAKQNTMTRSGFNWWLESESLPIFPEDKSP-- 329
            |.:||.|||..:..:...|..|::|.|:..||.|.:..:..|.||:|.|..:...:.||.|:.
Human   210 NRDWLQPLLHRVKEDYTRVVCPVIDIINLDTFTYIESASELRGGFDWSLHFQWEQLSPEQKARRL 274

  Fly   330 DST-PYRTPVLSGAM-AIDRNYFLNLGGFDEQLDTWEAEKFEISFKVWMCGGMMLYVPCARVGHI 392
            |.| |.|||:::|.: .||:.:|..||.:|..:|.|..|.|||||:||||||.:..|||:||||:
Human   275 DPTEPIRTPIIAGGLFVIDKAWFDYLGKYDMDMDIWGGENFEISFRVWMCGGSLEIVPCSRVGHV 339

  Fly   393 GKRPMKSISSPGYHNFLARNYKRVAEVWMDNYKKYVYDKNPKLYKMANAGLLFQRKTKRNALECK 457
            .::....:...|..|...:|.||.||||||.||:|.|...|...:.. .|.:..|...|..|.|:
Human   340 FRKKHPYVFPDGNANTYIKNTKRTAEVWMDEYKQYYYAARPFALERP-FGNVESRLDLRKNLRCQ 403

  Fly   458 TFDWYMTKVAPDFLKRYLALDSPLVFSGVIESVAFPGFCVDS--LNCRHTKPVVLARCTGHNSMP 520
            :|.||:..:.|:       |..|...|....::.....|::|  .|.:.|..:.|:.|.......
Human   404 SFKWYLENIYPE-------LSIPKESSIQKGNIRQRQKCLESQRQNNQETPNLKLSPCAKVKGED 461

  Fly   521 GEHQNWSLTQDHEIQLTNSKDDCLEAQGL-RSKSVWLFRCHKNGGNQYWYYNHRHRWIQQGQ--- 581
            .:.|.|:.|...:|.   .::.||....| ....|.|..| |||       :.|.:|.:.|.
Human   462 AKSQVWAFTYTQQIL---QEELCLSVITLFPGAPVVLVLC-KNG-------DDRQQWTKTGSHIE 515

  Fly   582 --IWVWCLEAQL-ASGHKVGKVLANKICDKNQLEQQW 615
              ....||:..: ..|.:.||.:....|:.:.:.|.|
Human   516 HIASHLCLDTDMFGDGTENGKEIVVNPCESSLMSQHW 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31776	NP_722909.2	pp-GalNAc-T	170..467	CDD:133004	120/300 (40%)
		beta-trefoil_Ricin_Pgant8-like	482..618	CDD:467339	31/143 (22%)
GALNT14	NP_001240755.1	pp-GalNAc-T	119..413	CDD:133004	120/300 (40%)
		beta-trefoil_Ricin-like	418..557	CDD:483949	32/146 (22%)