Protein Alignment CG31776 and Galnt1

DIOPT Version :10

• Sequence 1: NP_722909.2
• Gene: CG31776 / 33568
• FlyBaseID: FBgn0051776
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: NP_077349.1
• Gene: Galnt1 / 79214
• RGDID: 620358
• Length: 559
• Species: Rattus norvegicus
• Alignment Length: 548
• Identity: 181/548 - (33%)
• Similarity: 273/548 - (49%)
• Gaps: 72/548 - (13%)

  Fly   106 EDSNRRGL----------------GEQGRAVQLPNA---------KLNPDDFQDFYAELSDRIPL 145
            |:...|||                ||.|:.|.:|..         |:|     .|....|:.|..
  Rat    35 EEKKERGLPAGDVLELVQKPHEGPGEMGKPVVIPKEDQEKMKEMFKIN-----QFNLMASEMIAF 94

  Fly   146 NRSLPDTRPISCRKRKYLENLPNVTVIIAFHDEHLSVLLRSITSIINRSPVELLKQIVLVDDDSN 210
            ||||||.|...|:.:.|.::||..:|:|.||:|..|.|||::.|:|||||..::::||||||.|.
  Rat    95 NRSLPDVRLEGCKTKVYPDSLPTTSVVIVFHNEAWSTLLRTVHSVINRSPRHMIEEIVLVDDASE 159

  Fly   211 LPELGQQLEEIVAQ-NFPKIIHILRLPERRGSIKARMEAIRVSSCQVLVFLDSHIEVNTNWLPPL 274
            ...|.:.||..|.: ..|  :|::|:.:|.|.|:||::...||..||:.|||:|.|....||.||
  Rat   160 RDFLKRPLESYVKKLKVP--VHVIRMEQRSGLIRARLKGAAVSKGQVITFLDAHCECTVGWLEPL 222

  Fly   275 LEPIVINPHIVTRPILDAISRKTFAYAKQNTMTRSGFNWWLESESLPI----FPEDKSPDSTPYR 335
            |..|..:...|..||:|.||..||.|...:.||..||||.|.....|:    ....|...:.|.|
  Rat   223 LARIKHDRRTVVCPIIDVISDDTFEYMAGSDMTYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVR 287

  Fly   336 TPVLSGAM-AIDRNYFLNLGGFDEQLDTWEAEKFEISFKVWMCGGMMLYVPCARVGHIGKRPMKS 399
            ||.::|.: :|||:||..:|.:|..:|.|..|..||||::|.|||.:..|.|:.|||:.::....
  Rat   288 TPTMAGGLFSIDRDYFQEIGTYDAGMDIWGGENLEISFRIWQCGGTLEIVTCSHVGHVFRKATPY 352

  Fly   400 ISSPGYHNFLARNYKRVAEVWMDNYKKYVYDKNPKLYKMANAGLLFQRKTKRNALECKTFDWYMT 464
            ....|....:.:|.:|:||||||.:|.:.|..:|.:.|: :.|.:..|...|:.|:||.|.||:.
  Rat   353 TFPGGTGQIINKNNRRLAEVWMDEFKNFFYIISPGVTKV-DYGDISSRVGLRHKLQCKPFSWYLE 416

  Fly   465 KVAPD--FLKRYLALDSPLVFSGVIESVAFPGFCVDSLNCRHTKPVVLARCTGHNSMPGEHQNWS 527
            .:.||  ..:.|.:|       |.|.:|. ...|:|::..:..:.|.:..|.|    .|.:|.:|
  Rat   417 NIYPDSQIPRHYFSL-------GEIRNVE-TNQCLDNMARKENEKVGIFNCHG----MGGNQVFS 469

  Fly   528 LTQDHEIQLTNSKDDCLEAQGLRSKSVWLFRCHKNGGNQYWYYNH-----RHRWIQQGQIWVWCL 587
            .|.:.||:   :.|.||:...|.. .|.:.:||...|||.|.|:.     :|  :...|    ||
  Rat   470 YTANKEIR---TDDLCLDVSKLNG-PVTMLKCHHLKGNQLWEYDPVKLTLQH--VNSNQ----CL 524

  Fly   588 EAQLASGHKVGKVLANKICDKNQLEQQW 615
            :.......:|..:   :.|..:: .|||
  Rat   525 DKATEEDSQVPSI---RDCTGSR-SQQW 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31776	NP_722909.2	pp-GalNAc-T	170..467	CDD:133004	117/302 (39%)
		beta-trefoil_Ricin_Pgant8-like	482..618	CDD:467339	35/139 (25%)
Galnt1	NP_077349.1	Catalytic subdomain A	115..225		50/111 (45%)
		pp-GalNAc-T	119..419	CDD:133004	117/302 (39%)
		Catalytic subdomain B	285..347		28/61 (46%)
		beta-trefoil_Ricin_GALNT1	426..552	CDD:467344	37/149 (25%)