Protein Alignment CG31776 and GALNT16

DIOPT Version :10

• Sequence 1: NP_722909.2
• Gene: CG31776 / 33568
• FlyBaseID: FBgn0051776
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: NP_065743.2
• Gene: GALNT16 / 57452
• HGNCID: 23233
• Length: 558
• Species: Homo sapiens
• Alignment Length: 575
• Identity: 192/575 - (33%)
• Similarity: 272/575 - (47%)
• Gaps: 100/575 - (17%)

  Fly    98 WQDAIFFKEDSNRRGLGEQGR------------------------------AVQLPNAKLNPDDF 132
            |||.......|..||....||                              |.||   |...|.:
Human    25 WQDNRAHAASSGGRGAQRAGRRSEQLREDRTIPLIVTGTPSKGFDEKAYLSAKQL---KAGEDPY 86

  Fly   133 -QDFYAEL-SDRIPLNRSLPDTRPISCRKRKYLENLPNVTVIIAFHDEHLSVLLRSITSIINRSP 195
             |..:.:| ||::..:|.:.|||..||....|..:||..:|||.||:|..|.|||::.|::||:|
Human    87 RQHAFNQLESDKLSPDRPIRDTRHYSCPSVSYSSDLPATSVIITFHNEARSTLLRTVKSVLNRTP 151

  Fly   196 VELLKQIVLVDDDSNLPELGQQLEEIVAQNFPKIIHILRLPERRGSIKARMEAIRVSSCQVLVFL 260
            ..|:::|:||||.|:.||     :.::....|| :..||...|.|.|::|:....|::..||.||
Human   152 ANLIQEIILVDDFSSDPE-----DCLLLTRIPK-VKCLRNDRREGLIRSRVRGADVAAATVLTFL 210

  Fly   261 DSHIEVNTNWLPPLLEPIVINPHIVTRPILDAISRKTFAYAKQNTMTRSGFNWWL--ESESLPIF 323
            |||.||||.||||:|:.:..:...|..||:|.||...|||...:...|.||:|.|  :.|.:|:.
Human   211 DSHCEVNTEWLPPMLQRVKEDHTRVVSPIIDVISLDNFAYLAASADLRGGFDWSLHFKWEQIPLE 275

  Fly   324 PEDKSPDST-PYRTPVLSGAM-AIDRNYFLNLGGFDEQLDTWEAEKFEISFKVWMCGGMMLYVPC 386
            .:....|.| |.||||::|.: .||:::|.:||.:|.|:|.|..|.||:||:||||||.:..|||
Human   276 QKMTRTDPTRPIRTPVIAGGIFVIDKSWFNHLGKYDAQMDIWGGENFELSFRVWMCGGSLEIVPC 340

  Fly   387 ARVGHIGKRPMKSISSPGYHNF-------LARNYKRVAEVWMDNYKKYVYDKNPKLYKMANAGLL 444
            :||||:.::     ..|  :||       ..||.||.||||||.||:|.|:..|.....| .|.:
Human   341 SRVGHVFRK-----RHP--YNFPEGNALTYIRNTKRTAEVWMDEYKQYYYEARPSAIGKA-FGSV 397

  Fly   445 FQRKTKRNALECKTFDWYMTKVAPDFLKRYLALDSPLVFSGVIESVAFPGFCVDSLNCRHTKP-- 507
            ..|..:|..:.||:|.||:..|.|:       |..|:       ..|.||.....:||..::.
Human   398 ATRIEQRKKMNCKSFRWYLENVYPE-------LTVPV-------KEALPGIIKQGVNCLESQGQN 448

  Fly   508 ------VVLARCTGHNSMPGEHQNWSLTQDHEIQLTNSKDDCLEAQGLRSKS----VWLFRCHKN 562
                  :.:..|.|....|...|.| |..||.||   .:..||.|......|    |.|..|:..
Human   449 TAGDFLLGMGICRGSAKNPQPAQAW-LFSDHLIQ---QQGKCLAATSTLMSSPGSPVILQMCNPR 509

  Fly   563 GGNQYWYYNHRHRWIQQGQIWVWCLEAQLASGHKVGKVLANKICDKNQLEQQWKV 617
            .|.|.|  ..:..:||. .:...|||.:.|.       |....|..:...|||::
Human   510 EGKQKW--RRKGSFIQH-SVSGLCLETKPAQ-------LVTSKCQADAQAQQWQL 554

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31776	NP_722909.2	pp-GalNAc-T	170..467	CDD:133004	126/307 (41%)
		beta-trefoil_Ricin_Pgant8-like	482..618	CDD:467339	36/148 (24%)
GALNT16	NP_065743.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	33..54		5/20 (25%)
		Catalytic subdomain A	122..227		50/110 (45%)
		pp-GalNAc-T	126..420	CDD:133004	126/307 (41%)
		Catalytic subdomain B	286..348		33/61 (54%)
		beta-trefoil_Ricin_GALNT16	426..557	CDD:467357	37/150 (25%)