Protein Alignment CG31776 and Galnt18

DIOPT Version :10

• Sequence 1: NP_722909.2
• Gene: CG31776 / 33568
• FlyBaseID: FBgn0051776
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: NP_776100.2
• Gene: Galnt18 / 233733
• MGIID: 2446239
• Length: 622
• Species: Mus musculus
• Alignment Length: 580
• Identity: 167/580 - (28%)
• Similarity: 257/580 - (44%)
• Gaps: 102/580 - (17%)

  Fly    90 PQQEAIKEWQDAIFFKEDSNRRGLGEQGRAVQLPNAKLNPDDFQDFYAELSDRIPLNRSLPDTRP 154
            |::...:.:.|:..|......  |..:||.|.|...:     :..:.|.||||:||:|.|||.||
Mouse    84 PEEAEAEPFTDSSLFAHWGQE--LSPEGRRVALKQFQ-----YYGYNAYLSDRLPLDRPLPDLRP 141

  Fly   155 ISCRKRKYLENLPNVTVIIAFHDEHLSVLLRSITSIINRSPVELLKQIVLVDDDSNLPELGQQLE 219
            ..||...:.::||.|:::..|.:|.||||||||.|.:.|:|..|||:|:||||:|:..||.::|.
Mouse   142 SGCRNLSFPDSLPEVSIVFIFVNEALSVLLRSIHSAMERTPSHLLKEIILVDDNSSNEELKEKLT 206

  Fly   220 EIVAQ---NFPKIIHILRLPERRGSIKARMEAIRVSSCQVLVFLDSHIEVNTNWLPPLLEPIVIN 281
            |.|.:   ..|..|.::|..::.|.|::|:...|.::..|:...|:|:|.|..|..|:|..|..|
Mouse   207 EYVDKVNGQKPGFIKVVRHSKQEGLIRSRVSGWRAATAPVVALFDAHVEFNVGWAEPVLTRIKEN 271

  Fly   282 PHIVTRPILDAISRKTFAYAKQNTMTRSGFNW------------WLESESLPIFPEDKSPDSTPY 334
            ...:..|..|.|....|. .::..:...||:|            |.:.|:          .:.|.
Mouse   272 RKRIISPSFDNIKYDNFE-IEEYPLAAQGFDWELWCRYLNPPKAWWKLEN----------STAPI 325

  Fly   335 RTPVLSGAMAIDRNYFLNLGGFDEQLDTWEAEKFEISFK---------------VWMCGGMMLYV 384
            |:|.|.|...:||.||..:|..||.::.:..|..|:..:               ||.|||.:..:
Mouse   326 RSPALIGCFIVDRQYFEEIGLLDEGMEVYGGENVELGIRVSEISHTGLSSAPMMVWQCGGSVEVL 390

  Fly   385 PCARVGHIGKRPMKSISSPGYHNFLARNYKRVAEVWMDNYKKYVYD--KNPKLYKMANAGLLFQR 447
            ||:|:.||.:...........|  :.||..||||||||.:|.:||.  ..|:.....:.|.:..|
Mouse   391 PCSRIAHIERAHKPYTEDLTAH--VRRNALRVAEVWMDEFKSHVYMAWNIPQEDSGIDIGDITAR 453

  Fly   448 KTKRNALECKTFDWYMTKVAPDFLKRYLALDSPLVFSGVIESVAFPGFCVDSLNCRHTKPVVLAR 512
            |..|..|:||||.||:..|.|: ::.|    |.::..||:::......|:|........|:|..
Mouse   454 KALRKQLQCKTFRWYLVSVYPE-MRMY----SDIIAYGVLQNSLKTDLCLDQGPDTENVPIVYI- 512

  Fly   513 CTGHNSMPGEHQNWSLTQDHEIQL-----------------TNSKD---DCLEAQGLRSKSVWLF 557
            |  |...|   ||...|...:|.:                 .||:.   :|..|:..|.|..|.|
Mouse   513 C--HGMTP---QNVYYTSSQQIHVGILSPTVDDDDNRCLVDVNSRPRLIECSYAKAKRMKLHWQF 572

  Fly   558 RCHKNGGNQYWYYNHRHRWIQQGQIWVWCLEAQLASGHKVGKVLANKICDKNQLEQQWKV 617
               ..||:   ..|.:.:         .|||.|..|..:.|..|..:.|.    .|.|.:
Mouse   573 ---SQGGS---IQNRKSK---------RCLELQENSDMEFGFQLVLQKCS----GQHWTI 613

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31776	NP_722909.2	pp-GalNAc-T	170..467	CDD:133004	103/328 (31%)
		beta-trefoil_Ricin_Pgant8-like	482..618	CDD:467339	34/156 (22%)
Galnt18	NP_776100.2	Catalytic subdomain A	153..267		45/113 (40%)
		pp-GalNAc-T	157..473	CDD:133004	103/328 (31%)
		Catalytic subdomain B	324..400		24/75 (32%)
		beta-trefoil_Ricin_GALNT18	476..617	CDD:467353	36/167 (22%)