Protein Alignment CG31776 and Galnt11

DIOPT Version :10

• Sequence 1: NP_722909.2
• Gene: CG31776 / 33568
• FlyBaseID: FBgn0051776
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: NP_659157.1
• Gene: Galnt11 / 231050
• MGIID: 2444392
• Length: 608
• Species: Mus musculus
• Alignment Length: 655
• Identity: 202/655 - (30%)
• Similarity: 311/655 - (47%)
• Gaps: 115/655 - (17%)

  Fly    16 LLTSLVTTILM-----GKQIHRRLVKSMVKTTGEKDSLPARQLPKREISP-KVADFPPPLTLNQT 74
            |.||...|:|:     ..::.:.|....:|.:|.....|.:..|:....| :|.|  |....|:
Mouse    14 LFTSATWTVLLFIYFNFSEVTQPLRNVPIKGSGPHGPFPKKFYPRFTRGPGRVLD--PQFKANR- 75

  Fly    75 ELDILKIQRNNSFRLPQQEAIKEWQD--AIFFKEDSNRRGLGEQGRAVQLPNAKLNPDDFQDFYA 137
             :|.|   .||....|.:...|...:  .||.:.|...|.||.|..|               |..
Mouse    76 -IDRL---MNNHIEDPDKGLSKSSSELGMIFNERDQELRDLGYQKHA---------------FNM 121

  Fly   138 ELSDRIPLNRSLPDTRPISCRKRKYLENLPNVTVIIAFHDEHLSVLLRSITSIINRSPVELLKQI 202
            .:|:|:..:|.:||||...||::.|..:||..:::|.|::|..|.|||::.|:::|:|..||.:|
Mouse   122 LISNRLGYHRDVPDTRNAECRRKSYPTDLPTASIVICFYNEAFSALLRTVHSVVDRTPAHLLHEI 186

  Fly   203 VLVDDDSNLPELGQQLEEIVAQNFPKIIHILRLPERRGSIKARMEAIRVSSCQVLVFLDSHIEVN 267
            :||||.|:..:|..:|:|.:.:..|..:.::|..:|.|.|:.||.....::.:||||||||.|||
Mouse   187 ILVDDSSDFDDLKGELDEYIQRYLPAKVKVIRNMKREGLIRGRMIGAAHATGEVLVFLDSHCEVN 251

  Fly   268 TNWLPPLLEPIVINPHIVTRPILDAISRKTFAYAKQNTMTRSGFNWWL--ESESLPIFPEDKSPD 330
            ..||.|||..|:.:||.|..|::|.||..|.||: .:.:.|.||||.|  :.:.:|: .|...||
Mouse   252 VMWLQPLLAIILEDPHTVVCPVIDIISADTLAYS-SSPVVRGGFNWGLHFKWDLVPV-SELGGPD 314

  Fly   331 --STPYRTPVLSGAM-AIDRNYFLNLGGFDEQLDTWEAEKFEISFKVWMCGGMMLYVPCARVGHI 392
              :.|.|:|.::|.: |::|.||.:||.:|..:|.|..|..||||::|||||.:..:||:|||||
Mouse   315 GATAPIRSPTMAGGLFAMNRQYFNDLGQYDSGMDIWGGENLEISFRIWMCGGKLFILPCSRVGHI 379

  Fly   393 GKRPMKSISSPGYHNFLARNYKRVAEVWMDNYKKYVYDKNPKLYKMANAGLLFQRKTKRNALECK 457
             .|..:...||...:.:..|..|:|.||:|.||:..:...|.| |..:.|.:.:|...|..|.|:
Mouse   380 -FRKRRPYGSPEGQDTMTHNSLRLAHVWLDEYKEQYFSLRPDL-KNKSFGNISERVELRKKLGCQ 442

  Fly   458 TFDWYMTKVAPDFLKRYLALDSPLVFSGVIESVAFPGFCVDSLNCRHTKPVVLAR---------- 512
            :|.||:..:.|:                    :..||     .|.:..:||::.|
Mouse   443 SFKWYLDNIYPE--------------------MQIPG-----PNAKPQQPVLINRGPKRPRVLQR 482

  Fly   513 -------------CTGHNSMPG------------EHQNWSLTQDHEIQLTNSKDDCLEAQGLRSK 552
                         ..|.:|..|            ..|.|...:|||:.|.|..  ||:....||.
Mouse   483 GRLYHLQTNKCLVAQGRSSQKGGLVLLKTCDYGDPTQVWIYNEDHELILNNLL--CLDMSETRSS 545

  Fly   553 S-VWLFRCHKNGGNQYWYY--NHRHRWIQQGQIWVWCLEAQLASGHK--VGKVLANKICDKNQLE 612
            . ..|.:||.:||:|.|.:  |:|...:..||    ||........|  ||..    |||.:. .
Mouse   546 DPPRLMKCHGSGGSQQWTFGKNNRLYQVSVGQ----CLRVMDLMDQKGYVGMA----ICDGSS-S 601

  Fly   613 QQWKV 617
            |||::
Mouse   602 QQWRL 606

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31776	NP_722909.2	pp-GalNAc-T	170..467	CDD:133004	117/301 (39%)
		beta-trefoil_Ricin_Pgant8-like	482..618	CDD:467339	42/176 (24%)
Galnt11	NP_659157.1	Catalytic subdomain A	150..261		46/110 (42%)
		pp-GalNAc-T	154..452	CDD:133004	117/301 (39%)
		Catalytic subdomain B	319..381		30/62 (48%)
		beta-trefoil_Ricin_GALNT11	478..604	CDD:467318	34/136 (25%)