Protein Alignment CG31776 and Galnt12

DIOPT Version :10

• Sequence 1: NP_722909.2
• Gene: CG31776 / 33568
• FlyBaseID: FBgn0051776
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: NP_766281.1
• Gene: Galnt12 / 230145
• MGIID: 2444664
• Length: 576
• Species: Mus musculus
• Alignment Length: 573
• Identity: 162/573 - (28%)
• Similarity: 261/573 - (45%)
• Gaps: 121/573 - (21%)

  Fly    17 LTSLVTTILMGKQIHRRLVKSMVKTTGEKDSLPARQLPKREISPKVADFPPPLTLNQ--TELDIL 79
            |.:|:....:|..:..|.....|.....:..||.|..|   :.|:     |||..:.  ...:.:
Mouse    21 LLALLALAGLGALLRARSRSGTVDPGPPRTPLPGRHEP---VLPR-----PPLPADALGAHGEAV 77

  Fly    80 KIQ-RNNSFRLPQQEAIKEWQDAIFFKEDSNRRGLGEQGRAVQLPNAKLNPDDFQDFYAELSDRI 143
            ::| :....|| |:|::|:.|..|:                                   |||||
Mouse    78 RLQLQGEELRL-QEESVKQHQINIY-----------------------------------LSDRI 106

  Fly   144 PLNRSLPDTRPISCRKRKY-LENLPNVTVIIAFHDEHLSVLLRSITSIINRSPVELLKQIVLVDD 207
            .|:|.||:.....||:.|| .:|||..:|:|||::|..|.|||::.|::..||..||::::||||
Mouse   107 SLHRRLPERWNPLCREVKYDYDNLPKTSVVIAFYNEAWSTLLRTVYSVLETSPDILLEEVILVDD 171

  Fly   208 DSNLPELGQQLEEIVAQNFPKIIHILRLPERRGSIKARMEAIRVSSCQVLVFLDSHIEVNTNWLP 272
            .|:...|.::|...::| .|| :.::|...|.|.::||:.....:..:||.|||.|.|.:..||.
Mouse   172 YSDREHLKERLANELSQ-LPK-VRLIRASRREGLVRARLLGASAARGEVLTFLDCHCECHEGWLE 234

  Fly   273 PLLEPIVINPHIVTRPILDAISRKTFAYAKQNTMTR-SGFNWWL----------ESESLPIFPED 326
            |||:.|......|..|::|.|...||.|...:...: .||:|.|          |.:|:
Mouse   235 PLLQRIHEKESAVVCPVIDVIDWNTFEYLGNSGEPQIGGFDWRLVFTWHVVPQRERQSM------ 293

  Fly   327 KSPDSTPYRTPVLSGAM-AIDRNYFLNLGGFDEQLDTWEAEKFEISFKVWMCGGMMLYVPCARVG 390
            :||... .|:|.::|.: |:.:.||..||.:|..::.|..|..|.||::|.|||.:...||:.||
Mouse   294 RSPIDV-IRSPTMAGGLFAVSKRYFDYLGSYDTGMEVWGGENLEFSFRIWQCGGTLETHPCSHVG 357

  Fly   391 HIGKRPMKSISSPGYHNFLARNYKRVAEVWMDNYKKYVYDKNPKLYKMANAGLLFQRKTKRNALE 455
            |:..:     .:|...:....|..|.||||||.:|:..|.:||:. ::...|.:.:||..|..|:
Mouse   358 HVFPK-----QAPYSRSKALANSVRAAEVWMDEFKELYYHRNPQA-RLEPFGDVTERKKLRAKLQ 416

  Fly   456 CKTFDWYMTKVAPDFLKRYLALDSPLVFSGVIESVAFPGFCVDSLNCRHTKPVVLARCTGHNSMP 520
            ||.|.|::..|.|:.   ::..|.| .|.|::::....|:|:|     :..|       ..|.:.
Mouse   417 CKDFKWFLDTVYPEL---HVPEDRP-GFFGMLQNRGLRGYCLD-----YNPP-------NENHVE 465

  Fly   521 GEHQNWSLTQDHEIQLTNSKDDCLEAQGLRSKSVWLFRCHKNGGNQYWYYNHR 573
            | ||                             |.|:.||..|.||::.|..|
Mouse   466 G-HQ-----------------------------VLLYLCHGMGQNQFFEYTTR 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31776	NP_722909.2	pp-GalNAc-T	170..467	CDD:133004	102/308 (33%)
		beta-trefoil_Ricin_Pgant8-like	482..618	CDD:467339	19/92 (21%)
Galnt12	NP_766281.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	38..58		4/19 (21%)
		Catalytic subdomain A	130..239		43/110 (39%)
		pp-GalNAc-T	134..428	CDD:133004	102/308 (33%)
		Catalytic subdomain B	299..361		23/62 (37%)
		beta-trefoil_Ricin-like	438..574	CDD:483949	20/94 (21%)