Protein Alignment CG31776 and Galnt6

DIOPT Version :10

• Sequence 1: NP_722909.2
• Gene: CG31776 / 33568
• FlyBaseID: FBgn0051776
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: NP_766039.2
• Gene: Galnt6 / 207839
• MGIID: 1891640
• Length: 622
• Species: Mus musculus
• Alignment Length: 708
• Identity: 206/708 - (29%)
• Similarity: 313/708 - (44%)
• Gaps: 174/708 - (24%)

  Fly     5 LRLIVRLLLAILLTSLVTTILMGKQIHRR--------LVKSMVKT-TGEKDSLPARQLPK----R 56
            :||:.|..:::.|..|.:..::...|.::        :.|..:|: .|:||.:....|..    |
Mouse     1 MRLLRRRHMSLRLAMLGSVFMLFLFIRQKDVSNQEQAMEKPWLKSLAGQKDQVLDFMLGAVNNIR 65

  Fly    57 EISPK--VADFPPPLTLNQTELDILKIQRNNSFRLPQQEAIKEWQDAIFFKEDSNRRGLGEQGRA 119
            ::.||  :....||.||..|....|.     .|..|.:  :|.:.|    :...:....|..|:|
Mouse    66 DVMPKLQIRAPEPPQTLVSTNHSCLP-----GFYTPAE--LKPFWD----RPPQDPNSPGADGKA 119

  Fly   120 VQLP-----NAKLNPDDFQD--FYAELSDRIPLNRSL-PDTRPISCRKRKY--LENLPNVTVIIA 174
            .|..     ..|...:.::.  |.|..||||.|.||| |||||..|..:|:  ...||..:|||.
Mouse   120 FQKKEWTNLETKEKEEGYKKHCFNAFASDRISLQRSLGPDTRPPECVDQKFRRCPPLPTTSVIIV 184

  Fly   175 FHDEHLSVLLRSITSIINRSPVELLKQIVLVDDDSNLPELGQQLEEIVAQNFPKIIHILRLPERR 239
            ||:|..|.|||::.|:::.||..|||:|:||||.|....|.::||:.|.|  .:|:.::|..||:
Mouse   185 FHNEAWSTLLRTVYSVLHTSPAILLKEIILVDDASTDEHLKERLEQYVQQ--LQIVRVVRQRERK 247

  Fly   240 GSIKARMEAIRVSSCQVLVFLDSHIEVNTNWLPPLLEPI------VINPHIVTRPILDAISRKTF 298
            |.|.||:....|:..:||.|||:|.|....||.|||..|      |::|.|||      |...||
Mouse   248 GLITARLLGASVAQAEVLTFLDAHCECFHGWLEPLLARIAEDKTAVVSPDIVT------IDLNTF 306

  Fly   299 AYAKQ----NTMTRSGFNW-----WLESESLPIFPEDKSPDST-PYRTPVLSGAM-AIDRNYFLN 352
            .:::.    ...:|..|:|     |   |.||...:.:..|.| |.::|..:|.: :|.:.||.:
Mouse   307 QFSRPVQRGKAHSRGNFDWSLTFGW---EMLPEHEKQRRKDETYPIKSPTFAGGLFSISKAYFEH 368

  Fly   353 LGGFDEQLDTWEAEKFEISFKVWMCGGMMLYVPCARVGHIGKRPMKSISSPGYHNF------LAR 411
            :|.:|.|::.|..|..|:||:||.|||.:..:||:.|||:.:     ..||  |.|      :||
Mouse   369 IGTYDNQMEIWGGENVEMSFRVWQCGGQLEIIPCSVVGHVFR-----TKSP--HTFPKGTSVIAR 426

  Fly   412 NYKRVAEVWMDNYKKYVYDKNPKLYKMA---NAGLLFQRKTKRNALECKTFDWYMTKVAPDFLKR 473
            |..|:||||||:|||..|.:|.:..||.   |.|.:.:|...|..|.|..|.||:..|.|:.
Mouse   427 NQVRLAEVWMDDYKKIFYRRNLQAAKMVQENNFGDISERLRLREQLRCHNFSWYLHNVYPEM--- 488

  Fly   474 YLALDSPLVFSGVIESVAFPGFCVDSLNCRHTKPVVLARCTGHNSMPGEHQNWSLTQDHEIQLTN 538
             ...|....|.|.|:::. ...|:|               .|.|:..|
Mouse   489 -FVPDLNPTFYGAIKNLG-TNQCLD---------------VGENNRGG----------------- 519

  Fly   539 SKDDCLEAQGLRSKSVWLFRCHKNGGNQYWYYNH----RHRWIQQGQIWVWCLEAQLASGHKVGK 599
                         |.:.::.||..|||||:.|..    ||...:|     .||       |..|.
Mouse   520 -------------KPLIMYVCHNLGGNQYFEYTSQRDLRHNIGKQ-----LCL-------HASGS 559

  Fly   600 VLANKICD---KNQ---LEQQWKVGRN---------------------APYDPQREPH 630
            .|..:.|.   ||.   .:::|::.::                     ||.:| |:|:
Mouse   560 TLGLRSCQFVGKNSRVPKDEEWELTQDQLIRNSGSGTCLTSQDKKPAMAPCNP-RDPY 616

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31776	NP_722909.2	pp-GalNAc-T	170..467	CDD:133004	120/322 (37%)
		beta-trefoil_Ricin_Pgant8-like	482..618	CDD:467339	29/145 (20%)
Galnt6	NP_766039.2	Catalytic subdomain A	176..285		50/110 (45%)
		pp-GalNAc-T	180..485	CDD:133004	120/322 (37%)
		Catalytic subdomain B	348..410		24/61 (39%)
		beta-trefoil_Ricin-like	495..622	CDD:483949	34/181 (19%)