Protein Alignment CG31776 and GALNT5

DIOPT Version :10

• Sequence 1: NP_722909.2
• Gene: CG31776 / 33568
• FlyBaseID: FBgn0051776
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: XP_016858726.1
• Gene: GALNT5 / 11227
• HGNCID: 4127
• Length: 956
• Species: Homo sapiens
• Alignment Length: 673
• Identity: 206/673 - (30%)
• Similarity: 313/673 - (46%)
• Gaps: 143/673 - (21%)

  Fly    28 KQIHRRLVKSMV-KTTGEKDSLPARQLPKREISPKVADFPPPLTLNQTE------LDILKIQRNN 85
            |::.....|::. |..|:..|....:......|..:|  |..:.|:||.      |:..||  |.
Human   336 KEVSNSKTKTIFPKVLGKSQSKHISRNRSEMSSSSLA--PHRVPLSQTNHALTGGLEPAKI--NI 396

  Fly    86 SFRLPQQEAIKEWQDAIFFKEDS---------------NRRGLGEQGRAVQLPNAKLNPDDFQ-- 133
            :.:.|..|..:....|: ..|||               :.:..|:.||.|.:|:.|....:.:
Human   397 TAKAPSTEYNQSHIKAL-LPEDSGTHQVLRIDVTLSPRDPKAPGQFGRPVVVPHGKEKEAERRWK 460

  Fly   134 --DFYAELSDRIPLNRSLPDTRPISCRKRKYLENLPNVTVIIAFHDEHLSVLLRSITSIINRSPV 196
              :|...|||.||::|::.||||..|.::....|||..:||:.|.||..|.||||:.|:|||||.
Human   461 EGNFNVYLSDLIPVDRAIEDTRPAGCAEQLVHNNLPTTSVIMCFVDEVWSTLLRSVHSVINRSPP 525

  Fly   197 ELLKQIVLVDDDSNLPELGQQLEEIVAQNFPKIIHILRLPERRGSIKARMEAIRVSSCQVLVFLD 261
            .|:|:|:||||.|....|...|::.::| ||| :.||||.||.|.|:||:...:.::..||.|||
Human   526 HLIKEILLVDDFSTKDYLKDNLDKYMSQ-FPK-VRILRLKERHGLIRARLAGAQNATGDVLTFLD 588

  Fly   262 SHIEVNTNWLPPLLEPIVINPHIVTRPILDAISRKTFAYAKQNTMTRSGFNW-----WLESESLP 321
            ||:|.|..||.||||.:.::...|..|:::.|:.|..:|...:...|..|.|     |   .::|
Human   589 SHVECNVGWLEPLLERVYLSRKKVACPVIEVINDKDMSYMTVDNFQRGIFVWPMNFGW---RTIP 650

  Fly   322 --IFPEDKSPDSTPYRTPVLSGAM-AIDRNYFLNLGGFDEQLDTWEAEKFEISFKVWMCGGMMLY 383
              :..:::..::...|.||::|.: :||::||..||.:|..||.|..|..|:|||||||||.:..
Human   651 PDVIAKNRIKETDTIRCPVMAGGLFSIDKSYFFELGTYDPGLDVWGGENMELSFKVWMCGGEIEI 715

  Fly   384 VPCARVGHI---------GKRPMKSISSPGYHNFLARNYKRVAEVWMDNYKKYVYDKNPKLYKMA 439
            :||:|||||         .|..||::.         ||..||||||:|.||:..|.....|....
Human   716 IPCSRVGHIFRNDNPYSFPKDRMKTVE---------RNLVRVAEVWLDEYKELFYGHGDHLIDQG 771

  Fly   440 -NAGLLFQRKTKRNALECKTFDWYMTKVAPDFLKRYLALDSPLV-FSGVIESVAFPGFCVDSLNC 502
             :.|.|.|::..|..|:||:|.||:..|.||       |.:|:| .|||:.:||. |.|:...|
Human   772 LDVGNLTQQRELRKKLKCKSFKWYLENVFPD-------LRAPIVRASGVLINVAL-GKCISIEN- 827

  Fly   503 RHTKPVVLARCTGHNSMPGEHQNWSLTQDHEIQLTNSKDDCL----------------EAQGLRS 551
               ..|:|..|.|...:...:..|       ::|....:.|:                ..:||:
Human   828 ---TTVILEDCDGSKELQQFNYTW-------LRLIKCGEWCIAPIPDKGAVRLHPCDNRNKGLK- 881

  Fly   552 KSVWLFRCHKNGG-----------------------NQYWYYNHRHRWIQQGQIWVWCLEAQLAS 593
               ||   ||:..                       |...:.|::.         :.|||...:
Human   882 ---WL---HKSTSVFHPELLSNSACGSFPALLSLQVNHIVFENNQQ---------LLCLEGNFS- 930

  Fly   594 GHKVGKVLANKICDKNQLEQQWK 616
             .|:.||.|   ||..:..|:||
Human   931 -QKILKVAA---CDPVKPYQKWK 949

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31776	NP_722909.2	pp-GalNAc-T	170..467	CDD:133004	123/314 (39%)
		beta-trefoil_Ricin_Pgant8-like	482..618	CDD:467339	36/175 (21%)
GALNT5	XP_016858726.1	pp-GalNAc-T	499..800	CDD:133004	123/314 (39%)
		beta-trefoil_Ricin_GALNT5	806..954	CDD:467314	37/177 (21%)