Protein Alignment CG31776 and Galnt7

DIOPT Version :10

• Sequence 1: NP_722909.2
• Gene: CG31776 / 33568
• FlyBaseID: FBgn0051776
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: NP_653332.3
• Gene: Galnt7 / 108150
• MGIID: 1349449
• Length: 657
• Species: Mus musculus
• Alignment Length: 687
• Identity: 203/687 - (29%)
• Similarity: 323/687 - (47%)
• Gaps: 114/687 - (16%)

  Fly     9 VRLLLAILLTSLVTTILMGKQIHRRLVKSMVKTTGEKDSLPARQ---------LPKR---EISPK 61
            :||.:..:|.||   :::|..:...::.|.:.:..:..|..:|.         ||.|   .::|.
Mouse     1 MRLKIGFILRSL---LVVGSFLGLVVLWSSLSSRPDDQSPLSRMREDRDVNNPLPNRGGNGLAPG 62

  Fly    62 VADFPPPLT---LNQTELDILKIQRNNSFRLPQ--------QEAIKEWQDAIF------FKEDSN 109
            ...|.|.:.   :...|:|:..|:|.|..:..|        |..:.:.|...|      :::...
Mouse    63 DDRFKPVVPWPHVEGVEVDLESIRRKNKAKNEQERHAGGDSQRDVMQRQYLTFKPQTFTYRDPVL 127

  Fly   110 RRG-LG-------EQGRAVQLPNAK-----LNPDDFQDFYAEL---------SDRIPLNRSLPDT 152
            |.| ||       |....|..|..|     |.|:..|...|.:         ||.|.|:||:.|.
Mouse   128 RPGVLGNFEPKEPEPHGVVGGPGEKAKPLVLGPEYKQAVQASIKEFGFNMVASDMISLDRSVNDL 192

  Fly   153 RPISCRKRKYLENLPNVTVIIAFHDEHLSVLLRSITSIINRSPVELLKQIVLVDDDSNLPELGQQ 217
            |...|:...|.|||...:|:|.||:|..|.|:|::.|:|.|:|.:.|.:|||:||.||...|.::
Mouse   193 RQEECKYWHYDENLLTSSVVIVFHNEGWSTLMRTVHSVIKRTPRKYLAEIVLIDDFSNKEHLKEK 257

  Fly   218 LEEIVAQNFPKIIHILRLPERRGSIKAR-MEAIRVSSCQVLVFLDSHIEVNTNWLPPLLEPIVIN 281
            |:|.: :.:..::.:.|...|.|.|:|| :.|.:....|||::||:|.||..||..||:.||..:
Mouse   258 LDEYI-KLWNGLVKVFRNERREGLIQARSIGAQKAKLGQVLIYLDAHCEVAVNWYAPLVAPISKD 321

  Fly   282 PHIVTRPILDAISRKTFAYAKQ-----NTMTRSGFNWWLESESLPIFPEDKSPDST---PYRTPV 338
            ..|.|.||:|.||..|:....|     :...|..::|.:..:.:|:...:|....|   |||:|.
Mouse   322 RTICTVPIIDVISGNTYEIIPQGGGDEDGYARGAWDWSMLWKRVPLTSREKRLRKTKTEPYRSPA 386

  Fly   339 LSGAM-AIDRNYFLNLGGFDEQLDTWEAEKFEISFKVWMCGGMMLYVPCARVGHI-------GKR 395
            ::|.: ||::::|..||.:|..|..|..|.||||:|:|.|||.:|:|||:|||||       |..
Mouse   387 MAGGLFAIEKDFFFELGLYDPGLQIWGGENFEISYKIWQCGGKLLFVPCSRVGHIYRLEGWQGNP 451

  Fly   396 PMKSI-SSPGYHNFLARNYKRVAEVWMDNYKKYVYDKNPKLYKMANAGLLFQRKTKRNALECKTF 459
            |...: |||     ..:||.||.|||.|.||.|.|...|: .|....|.:.:.|..|....||:|
Mouse   452 PPLYVGSSP-----TLKNYVRVVEVWWDEYKDYFYASRPE-SKALPYGDISELKKFREDHNCKSF 510

  Fly   460 DWYMTKVAPDFLKRYLALDSPL----VFSGVIESVAFPGFCVDSLNCRHTKPVVLARCTGHNSMP 520
            .|:|.::|.|....|     ||    |..|.|..:. ..:|:||:...:...|.|..|  |..
Mouse   511 KWFMEEIAYDITAHY-----PLPPRNVEWGEIRGLE-TAYCIDSMGKTNGGFVELGPC--HRM-- 565

  Fly   521 GEHQNWSLTQDHEIQLTNSKDDCLEAQGLRSKSVWLFRCHKNGGNQYWYYNHRHRW--IQQGQIW 583
            |.:|.:.:.:.:::.   ..|.|| .:|.....|.:..|:.|...::.|:...||:  |..|:
Mouse   566 GGNQLFRINEANQLM---QYDQCL-TKGPDGSKVMITHCNLNEFKEWQYFKSLHRFTHITSGK-- 624

  Fly   584 VWCLEAQLASGHKVGKVLAN---KICDKNQLEQQWKV 617
              ||:.        .:||..   ..||.:::.|:|::
Mouse   625 --CLDR--------SEVLHQVFISTCDSSKMTQKWEM 651

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31776	NP_722909.2	pp-GalNAc-T	170..467	CDD:133004	117/314 (37%)
		beta-trefoil_Ricin_Pgant8-like	482..618	CDD:467339	32/141 (23%)
Galnt7	NP_653332.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	30..66		6/35 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	83..105		4/21 (19%)
		Catalytic subdomain A	206..317		43/111 (39%)
		pp-GalNAc-T	210..518	CDD:133004	117/314 (37%)
		Catalytic subdomain B	381..443		32/61 (52%)
		beta-trefoil_Ricin_GALNT7	530..653	CDD:467315	32/143 (22%)