Protein Alignment CG31776 and POC1B-GALNT4

DIOPT Version :10

• Sequence 1: NP_722909.2
• Gene: CG31776 / 33568
• FlyBaseID: FBgn0051776
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: NP_001186710.1
• Gene: POC1B-GALNT4 / 100528030
• HGNCID: 42957
• Length: 575
• Species: Homo sapiens
• Alignment Length: 580
• Identity: 188/580 - (32%)
• Similarity: 285/580 - (49%)
• Gaps: 72/580 - (12%)

  Fly    69 LTLNQTELDILKIQRNNSFRLPQ-QEAIKEWQDAIFFKEDSNRRGLGEQGRAVQLPNAKLNPDDF 132
            |:.|..:|...:.:...|.||.. |:..::....::.|..::.|.|||.|:|.:|   :||.|:.
Human    26 LSPNGKQLGAGRARELGSRRLSDLQKNTEDLSRPLYKKPPADSRALGEWGKASKL---QLNEDEL 87

  Fly   133 Q------DFYA---ELSDRIPLNRSLPDTRPISCRKRKY-LENLPNVTVIIAFHDEHLSVLLRSI 187
            :      :.||   .|||||.|:|.:.|.|...|:.:|: ...||..:|||||::|..|.|||:|
Human    88 KQQEELIERYAINIYLSDRISLHRHIEDKRMYECKSQKFNYRTLPTTSVIIAFYNEAWSTLLRTI 152

  Fly   188 TSIINRSPVELLKQIVLVDDDSNLPELGQQLEEIVAQNFPKIIHILRLPERRGSIKARMEAIRVS 252
            .|::..||..|||:|:||||.|:...|..|||..:: |..: :.::|..:|.|.::||:.....:
Human   153 HSVLETSPAVLLKEIILVDDLSDRVYLKTQLETYIS-NLDR-VRLIRTNKREGLVRARLIGATFA 215

  Fly   253 SCQVLVFLDSHIEVNTNWLPPLLEPIVINPHIVTRPILDAISRKTFAYAKQ-NTMTRSGFNWWL- 315
            :..||.|||.|.|.|:.||.||||.|..:...|..|::|.|...||.:..| ......||:|.|
Human   216 TGDVLTFLDCHCECNSGWLEPLLERIGRDETAVVCPVIDTIDWNTFEFYMQIGEPMIGGFDWRLT 280

  Fly   316 -ESESLPIFPEDKSPDS-TPYRTPVLSGAM-AIDRNYFLNLGGFDEQLDTWEAEKFEISFKVWMC 377
             :..|:|....|:.... .|.|:|.::|.: |:.:.||..||.:|..::.|..|..|:||:||.|
Human   281 FQWHSVPKQERDRRISRIDPIRSPTMAGGLFAVSKKYFQYLGTYDTGMEVWGGENLELSFRVWQC 345

  Fly   378 GGMMLYVPCARVGHI------GKRPMKSISSPGYHNFLARNYKRVAEVWMDNYKKYVYDKNPKLY 436
            ||.:...||:.|||:      ..||          ||| :|..|.||||||.||::.|::||...
Human   346 GGKLEIHPCSHVGHVFPKRAPYARP----------NFL-QNTARAAEVWMDEYKEHFYNRNPPAR 399

  Fly   437 KMANAGLLFQRKTKRNALECKTFDWYMTKVAPDFLKRYLALDSPLVFSGVIESVAFPGFCVDSLN 501
            |.| .|.:.:||..|..|.||:||||:..|.|:.   ::..|.| .:.|.|.|......|:| .|
Human   400 KEA-YGDISERKLLRERLRCKSFDWYLKNVFPNL---HVPEDRP-GWHGAIRSRGISSECLD-YN 458

  Fly   502 CRHTKP----VVLARCTGHNSMPGEHQNWSLTQDHEIQLTNSKDDCLEAQGLRSKSVWLFRCHKN 562
            .....|    :.|..|.|.    |.:|.:..|.:.||:..:..:.|.|... :...|.:..|.|:
Human   459 SPDNNPTGANLSLFGCHGQ----GGNQFFEYTSNKEIRFNSVTELCAEVPE-QKNYVGMQNCPKD 518

  Fly   563 G----GNQYWYYN------HRHRWIQQGQIWVWCLEA-QLASGHKVGKVLANKICDKNQL 611
            |    .|..|::.      |.|..:        ||.| :...|....::......||||:
Human   519 GFPVPANIIWHFKEDGTIFHPHSGL--------CLSAYRTPEGRPDVQMRTCDALDKNQI 570

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31776	NP_722909.2	pp-GalNAc-T	170..467	CDD:133004	118/307 (38%)
		beta-trefoil_Ricin_Pgant8-like	482..618	CDD:467339	33/145 (23%)
POC1B-GALNT4	NP_001186710.1	pp-GalNAc-T	135..429	CDD:133004	118/307 (38%)
		beta-trefoil_Ricin_GALNT4	439..574	CDD:467347	34/147 (23%)