Protein Alignment Pif1 and pif1

DIOPT Version :9

• Sequence 1: NP_001285587.1
• Gene: Pif1 / 33567
• FlyBaseID: FBgn0031540
• Length: 663
• Species: Drosophila melanogaster
• Sequence 2: NP_942102.1
• Gene: pif1 / 326729
• ZFINID: ZDB-GENE-030131-4928
• Length: 639
• Species: Danio rerio
• Alignment Length: 652
• Identity: 293/652 - (44%)
• Similarity: 404/652 - (61%)
• Gaps: 40/652 - (6%)

  Fly     3 LNDAVLTCAVNMEWTNAVGITGRKLAYKTATLRLVRNDLRELFVEVTPEKLKPLKFKLKDLMVHK 67
            :..|.|.|.|.:|..|..|...::...:..|:.|.||:.:|:.:.|...| .|..|.|:|..:..
Zfish     5 MEPAELQCTVAVERLNPAGQAIKRQLIRKGTVTLGRNEFQEMILRVHDGK-APQNFMLRDFQLFT 68

  Fly    68 KFMSEGKATFNFKAEKCTLYLSNAPPGTLMFFLRTIFVKMNGNEGGSQPDDATLQKKLREHLMSG 132
            :|..:||.|..|..|...:.:|:.||..|..||:|:.:|...::......|       ||.|.:|
Zfish    69 RFAKDGKCTVKFVPENTQVLVSDCPPDRLKMFLKTLSIKHQASQSSKPLSD-------REKLRAG 126

  Fly   133 KPSSFNDVSPVTTAEMILARKKAGLLSKGSVTTP-SPQGAKKRRFEELKEEKERGTMP------- 189
            .|.:|..|||:...::    :||..| :..|..| .|:...:|...::..::::...|
Zfish   127 LPRAFETVSPLQLKDV----EKANEL-RSRVNAPMQPRCLAERPVNKVLGDRKQVKRPRPDCDAS 186

  Fly   190 AAKKLYAS-----TTDESLRLSEEQMEVLRACTSGKSVFFTGSAGTGKSFLLRRIISALPPDGTV 249
            ..|.|:.:     ....:.:||:||..||.|..|||:|||||||||||||||:||:.:|||..|.
Zfish   187 PVKALHPNKKPVLVLPVAQKLSKEQTAVLNAVLSGKNVFFTGSAGTGKSFLLKRIVGSLPPKSTY 251

  Fly   250 ATASTGVAACLIGGTTLHAFAGIGGGDATMQRCLELASRPANAQTWRKCKRLIIDEISMVDGQFF 314
            ||||||||||.|||||||:|||||.|.|.:::|:|||.||...:.|..||.|||||||||:.:||
Zfish   252 ATASTGVAACHIGGTTLHSFAGIGSGSAPLEQCIELAQRPGVLRHWTSCKHLIIDEISMVEAEFF 316

  Fly   315 EKIEAVARHIRRNDRPFGGIQLILCGDFLQLPPVIKGDFGAAPTATPQQRFCFQSSAWETCIQCV 379
            :|:||:||.|||:..||||||||:||||||||||.||        ..:..|||||.:|..||...
Zfish   317 DKLEAIARSIRRSTEPFGGIQLIVCGDFLQLPPVTKG--------KEKANFCFQSRSWRKCIHMN 373

  Fly   380 YELKQVHRQSDPEFVKILNHLRIGHVNDSITSRLAATSKQKIEGNGILATQLCSHTNDANSINES 444
            .||.:|.||:|..|:.:|..:|:|.|.:.:|::|..::...||.:|||||:||:|.:|....||:
Zfish   374 MELMEVRRQTDKTFISLLQAVRVGRVTEEVTAQLLKSANHCIERDGILATRLCTHKDDVELTNEN 438

  Fly   445 KLENLDGDKILFKADDSDASMTRTLDQQIQAPSQLYLKVNAQVMLLKNINISNGLVNGARGVVVR 509
            ||:.|.|...:::|.|||..:.:|:|.|......|.|||.|||||.||:::..|||||||||||.
Zfish   439 KLKQLPGVVRMYEAVDSDPMLVQTIDAQSPVSRLLQLKVGAQVMLTKNLDVQRGLVNGARGVVVD 503

  Fly   510 ME---KDLPVVRFKNNQEYVCKHERWIIKTASGNHITRRQVPLKLAWAFSIHKSQGLTLDCVEMS 571
            .:   :.||.|||......|.|.|||:.|...|.:::|:|:|||||||.|||||||:||||||:|
Zfish   504 FQPGNQGLPRVRFLCGAVEVMKRERWMFKAPGGLYLSRQQLPLKLAWAISIHKSQGMTLDCVEIS 568

  Fly   572 LSKVFEAGQAYVALSRAKSLQSIRILDFDAKQVWANPHVLQFYKGFR--RKLMDTTMIP-LGPKN 633
            |::|||:||||||||||:||:.:|::|||.:.|.||..||.|||..|  |.||.::|.. :|..|
Zfish   569 LARVFESGQAYVALSRARSLEGLRVMDFDPRVVQANQDVLIFYKRLRKERLLMQSSMNDFVGQSN 633

  Fly   634 KD 635
            |:
Zfish   634 KE 635

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pif1	NP_001285587.1	P-loop_NTPase	205..510	CDD:304359	170/304 (56%)
pif1	NP_942102.1	P-loop_NTPase	206..504	CDD:304359	170/305 (56%)
		Herpes_Helicase	<551..598	CDD:280797	34/46 (74%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594788
Domainoid	1	1.000	252	1.000	Domainoid score	I2050
eggNOG	1	0.900	-	-		E1_COG0507
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H99775
Inparanoid	1	1.050	517	1.000	Inparanoid score	I1250
OMA	1	1.010	-	-		QHG55717
OrthoDB	1	1.010	-	-		D413010at33208
OrthoFinder	1	1.000	-	-		FOG0002406
OrthoInspector	1	1.000	-	-		oto38753
orthoMCL	1	0.900	-	-		OOG6_100049
Panther	1	1.100	-	-	LDO	PTHR23274
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R921
SonicParanoid	1	1.000	-	-		X3535
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	15	14.840