Protein Alignment Pif1 and Pif1

DIOPT Version :9

• Sequence 1: NP_001285587.1
• Gene: Pif1 / 33567
• FlyBaseID: FBgn0031540
• Length: 663
• Species: Drosophila melanogaster
• Sequence 2: XP_030100025.1
• Gene: Pif1 / 208084
• MGIID: 2143057
• Length: 676
• Species: Mus musculus
• Alignment Length: 596
• Identity: 257/596 - (43%)
• Similarity: 355/596 - (59%)
• Gaps: 52/596 - (8%)

  Fly     2 DLNDAVLTCAVNMEWTNAVGITGRKLAYKTATLRLVRNDLRELFVEV-TPEKL-KPLKFKLKDLM 64
            :.:||.|.|.|.:|..:..|...::.|.:.|.|.|.||:.|||.:.: .|... :|..|.|:.:.
Mouse    24 ECDDAELRCRVAVEELSPGGQPRKRQALRAAELSLGRNERRELMLRLQAPGPTGRPRCFPLRAVR 88

  Fly    65 VHKKFMSEGKATFNFK------AEKCTLYLSNAPPGTLMFFLRTIFVKMNGNEGGSQPDDATLQK 123
            :..:|.:.|::|....      |....|.||:.||..|..||||:.:|:....|   |..|:
Mouse    89 LFTRFAATGRSTLRLPTDGVPGAGSVQLLLSDCPPERLRRFLRTLRLKLAVAPG---PGPAS--- 147

  Fly   124 KLREHLMSGKPSSFNDVSPVTTAEMILARKKAGLLSKGSVTTPSPQGA-KKRRFE-ELKEEKERG 186
             .|..|:..:|..|..:|||...|:           :.:..|.:|..| :||..| :...|..|.
Mouse   148 -ARAQLLGPRPRDFVTISPVQPEEL-----------QRAAATKAPDSALEKRPMESQTSTEAPRW 200

  Fly   187 TMPAAKKLYASTTDESLRLSEEQMEVLRACTSGKSVFFTGSAGTGKSFLLRRIISALPPDGTVAT 251
            .:|..|....||..   :|||||..|||....|:|:|||||||||||:||:.|:.:|||.|||||
Mouse   201 PLPVKKLRMPSTKP---KLSEEQAAVLRMVLKGQSIFFTGSAGTGKSYLLKHILGSLPPTGTVAT 262

  Fly   252 ASTGVAACLIGGTTLHAFAGIGGGDATMQRCLELASRPANAQTWRKCKRLIIDEISMVDGQFFEK 316
            ||||||||.|||||||||||||.|.|.:.:|:.||:||...|.|..|:||:|||||||:..||:|
Mouse   263 ASTGVAACHIGGTTLHAFAGIGSGQAPLAQCMALANRPGVRQGWLNCQRLVIDEISMVEADFFDK 327

  Fly   317 IEAVARHIRRNDRPFGGIQLILCGDFLQLPPVIKGDFGAAPTATPQQRFCFQSSAWETCIQCVYE 381
            :|||||.:|:..:||||||||:||||||||||.||        :.|.:||||:.:|..|:..:.|
Mouse   328 LEAVARAVRQQKKPFGGIQLIICGDFLQLPPVTKG--------SQQPQFCFQAKSWRRCVPVILE 384

  Fly   382 LKQVHRQSDPEFVKILNHLRIGHVNDSITSRLAATSKQKIEGNGILATQLCSHTNDANSINESKL 446
            |.:|.||:|..|:.:|..:|:|..:|.:|.:|.||:..|:..:||:||:||:|.:|....||..|
Mouse   385 LTEVWRQADQTFISLLQAVRLGRCSDEVTRQLRATAAHKVGRDGIVATRLCTHQDDVALTNEKWL 449

  Fly   447 ENLDGDKILFKADDSDASMTRTLDQQIQAPSQLYLKVNAQVMLLKNINISNGLVNGARGVVVRME 511
            :.|.||...|:|.|||..::||||.|......|.||:.|||||:||:.:|.|||||||||||..|
Mouse   450 KALPGDVHSFEAIDSDPELSRTLDAQCPVSRVLQLKLGAQVMLVKNLAVSRGLVNGARGVVVGFE 514

  Fly   512 KD---LPVVRFKNNQEYVCKHERWIIKTASGNHITRRQVPLKLAWAFSIHKSQGLTLDCVEMSLS 573
            .:   ||.|||......|.:.:||.::...|.:::|:|:||:||||.|||||| :|:.|
Mouse   515 SEGRGLPRVRFLCGITEVIRTDRWTVQVTGGQYLSRQQLPLQLAWAISIHKSQ-VTIRC------ 572

  Fly   574 KVFEAGQAYVA 584
               ..|||.::
Mouse   573 ---RGGQAMLS 580

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pif1	NP_001285587.1	P-loop_NTPase	205..510	CDD:304359	170/304 (56%)
Pif1	XP_030100025.1	DEAD-like_helicase_N	215..513	CDD:391939	158/297 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167849216
Domainoid	1	1.000	252	1.000	Domainoid score	I2084
eggNOG	1	0.900	-	-		E1_COG0507
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H99775
Inparanoid	1	1.050	497	1.000	Inparanoid score	I1373
Isobase	1	0.950	-	0	Normalized mean entropy	S2212
OMA	1	1.010	-	-		QHG55717
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002406
OrthoInspector	1	1.000	-	-		oto93708
orthoMCL	1	0.900	-	-		OOG6_100049
Panther	1	1.100	-	-	LDO	PTHR23274
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R921
SonicParanoid	1	1.000	-	-		X3535
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.740