Protein Alignment Pif1 and Pif1

DIOPT Version :10

• Sequence 1: NP_608782.1
• Gene: Pif1 / 33567
• FlyBaseID: FBgn0031540
• Length: 663
• Species: Drosophila melanogaster
• Sequence 2: XP_317740.5
• Gene: Pif1 / 1278190
• VectorBaseID: AGAMI1_010271
• Length: 668
• Species: Anopheles gambiae
• Alignment Length: 686
• Identity: 397/686 - (57%)
• Similarity: 495/686 - (72%)
• Gaps: 43/686 - (6%)

  Fly     1 MDLNDAVLTCAVNMEWTNAVGITGRKLAYKTATLRLVRNDLRELFVEVTPEKLKPLKFKLKDLMV 65
            ||.|||.||||||:||.:|.|.|.||.|:|.|||||:||.|:|:|:||:..|...::.||:.:.|
Mosquito     1 MDPNDASLTCAVNLEWNDAHGTTTRKFAHKEATLRLIRNALKEMFLEVSAPKTSTMQLKLRGVQV 65

  Fly    66 HKKFMSEGKATFNFKAEKCTLYLSNAPPGTLMFFLRTIFVKM-NGNEGGSQPDDA-TLQKKLREH 128
            |.|||:||||:..|..|||||:|||||||.|:.||:.:|||: |||..|.||... .|.|:.|..
Mosquito    66 HSKFMAEGKASIKFNDEKCTLFLSNAPPGLLVQFLKVVFVKLTNGNGAGGQPKSKDELLKQSRAQ 130

  Fly   129 LMSGKP-SSFNDVSPVTTAEMILARKKAGLLSKGSVTTPSPQGAKKRRFEELKEEKERGTMPAAK 192
            :::||. :.::|||||||.|:..|||.|  ..|||:|||||...:||     ..:...|..|..|
Mosquito   131 MLAGKSMNQYDDVSPVTTTELNRARKLA--TGKGSLTTPSPSQKRKR-----LSDGGTGDRPKPK 188

  Fly   193 KLYASTTDE-----SLRLSEEQMEVLRACTSGKSVFFTGSAGTGKSFLLRRIISALPPDGTVATA 252
            ||.:...||     :::|:|||..:|.|..||:|:|||||||||||||||:||:|||||||:|||
Mosquito   189 KLLSENVDEAGSGDAIQLNEEQKRILSASQSGQSLFFTGSAGTGKSFLLRKIIAALPPDGTIATA 253

  Fly   253 STGVAACLIGGTTLHAFAGIGGGDATMQRCLELASRPANAQTWRKCKRLIIDEISMVDGQFFEKI 317
            |||||||||||||||:|||||.||||:|.|.|.||||..||.||||||||||||||::..|||||
Mosquito   254 STGVAACLIGGTTLHSFAGIGTGDATLQNCYEKASRPNTAQAWRKCKRLIIDEISMIEADFFEKI 318

  Fly   318 EAVARHIRRNDRPFGGIQLILCGDFLQLPPVIKGDFGAAP-TATPQQ--------------RFCF 367
            |||||::|:||:|||||||||||||.|||||     |..| .:.|.|              ||||
Mosquito   319 EAVARYVRKNDKPFGGIQLILCGDFFQLPPV-----GRLPDRSRPGQYSQDAQQDDESGRVRFCF 378

  Fly   368 QSSAWETCIQCVYELKQVHRQSDPEFVKILNHLRIGHVNDSITSRLAATSKQKIEGNGILATQLC 432
            :|.||..|||..|||..||||.|.||:.|||.:|||.|.|.|:.||..|:.|:||..||||||||
Mosquito   379 ESKAWRECIQASYELTIVHRQRDQEFISILNSIRIGRVTDEISERLRKTASQRIETEGILATQLC 443

  Fly   433 SHTNDANSINESKLENLDGDKILFKADDSDASMTRTLDQQIQAPSQLYLKVNAQVMLLKNINISN 497
            |||::.::||::|||.|..:..||:|.|||....:.||..:|||::|.||:.||||||||.|||.
Mosquito   444 SHTSEVDAINQAKLEALRTEAKLFEAKDSDPYSVKQLDMMLQAPAKLTLKIGAQVMLLKNYNISE 508

  Fly   498 GLVNGARGVVVRMEKDLPVVRFKNNQEYVCKHERWIIKTASGNHITRRQVPLKLAWAFSIHKSQG 562
            |||||||||:|...:.||:|:|| .:|.:.:||:|.:||.||..:||.|:|||||||||||||||
Mosquito   509 GLVNGARGVIVNFVQGLPLVKFK-RRELLIRHEKWSVKTGSGMVLTRIQLPLKLAWAFSIHKSQG 572

  Fly   563 LTLDCVEMSLSKVFEAGQAYVALSRAKSLQSIRILDFDAKQVWANPHVLQFYKGFRRKLMD-TTM 626
            |||||||:||||||||||||||||||:||.|||:||||.:|||||..||::|:..|:.:.: ..|
Mosquito   573 LTLDCVELSLSKVFEAGQAYVALSRAQSLDSIRVLDFDLRQVWANTKVLEYYRYLRKMIANGNHM 637

  Fly   627 IPLGPKNKDKKPGDKAANSALAKLKKSLINKPLVSI 662
            .|:..|.|.||     :.||:. |.||:::|||::|
Mosquito   638 EPVAVKRKLKK-----SLSAMG-LSKSIMDKPLMTI 667

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pif1	NP_608782.1	RecD	<190..591	CDD:440273	266/420 (63%)
		DEXSc_Pif1_like	208..387	CDD:350795	130/193 (67%)
Pif1	XP_317740.5	None