Protein Alignment msl-2 and Msl2

DIOPT Version :9

• Sequence 1: NP_523467.1
• Gene: msl-2 / 33565
• FlyBaseID: FBgn0005616
• Length: 773
• Species: Drosophila melanogaster
• Sequence 2: XP_236567.5
• Gene: Msl2 / 315959
• RGDID: 1310355
• Length: 577
• Species: Rattus norvegicus
• Alignment Length: 637
• Identity: 142/637 - (22%)
• Similarity: 235/637 - (36%)
• Gaps: 170/637 - (26%)

  Fly     2 AQTAYLKVTRIAMRSASNLSKRRVEELNSGLGELRQLLSCVVCCQLLVDPYSPKGKRCQHNVCRL 66
            |...|:..:|:.:..... ..:...|:|..|...||.|||.||..||.||.:|....|||.||:.
  Rat     6 ATALYISASRLVLNYDPG-DPKAFTEINRLLPYFRQSLSCCVCGHLLQDPIAPTNSTCQHYVCKS 69

  Fly    67 CLRGKKHLF-PSCTQCEGCSDFKTYEENRMMAAQLLCYKTLCVHLLHSALFGELAGMRPQVAREL 130
            | :|||.:. |||:.|:   |::.:|||:.::..:.|||.||.::..:.|           ||::
  Rat    70 C-KGKKMMMKPSCSWCK---DYEQFEENKQLSILVNCYKKLCEYITQTTL-----------ARDI 119

  Fly   131 VPRIKLPPKTTQEFIREGSNISDTFDIFLPQPDLPFLKDMPTSLPAETPPTSAVTTPELPYDHHL 195
            :..:.. .......:.:||       :|..:          |..|:::..|..:|...||
  Rat   120 IEAVDC-SSDILALLNDGS-------LFCEE----------TEKPSDSSFTLCLTHSPLP----- 161

  Fly   196 NISDIEAEAAATAEQGHFSPLPLLPTGSRMGMLSHAGQIVIATESSESGFMDQAWTDQVDLSGTV 260
                      :|:|          ||......||         ..|||       |..:.:..:|
  Rat   162 ----------STSE----------PTADPQAALS---------PMSES-------TLSIAIGSSV 190

  Fly   261 SVSKYTNSG---NNFAVSYVMPTSATTKFDPQELQIGQVVQMADSTQLAVLAAVEETVETSTQLT 322
            .....|.:|   :.|.::...|.      .|..:.:...|.:             :|.:.|..|.
  Rat   191 INGLPTYNGLSIDRFGINIPSPE------HPNTIDVCNTVDI-------------KTEDLSDSLP 236

  Fly   323 VLSTTVEETVETSTQLEVLTSAEEPNEISDQLANLQVEESDEAL--VEETVEEAEGTSIPSEVVA 385
            .:..|| .|...||.:::.:.:|:            ::..|..|  |||.:...|..| .:||..
  Rat   237 PVCDTV-ATDLCSTGIDICSFSED------------IKPGDSLLLSVEEVLRSLETVS-NTEVCC 287

  Fly   386 EHMEEDQHLDVHTSQSPTQTEMEEAVEEHVATKTQLGHVQTELQDAESLQKDFEDAKAAAEEAKE 450
            .:::  .:|:...|..|......:::..:|...|...........|..........::.:|...|
  Rat   288 SNLQ--PNLEATVSNGPFLQLSSQSLSHNVFMSTSPALHGLSCTAATPKVAKLNRKRSRSESDSE 350

  Fly   451 KEKDLHAISAELQKEDSDEPTLKRKRTRTLKASQAAKIEPV---------PSEVKTKVQSGKGAL 506
            |.:.| .||..::     .|||......|:|......::|:         |...||.:.|.|...
  Rat   351 KVQPL-PISTIIR-----GPTLGASAPVTVKRESKLSLQPIATVPNGGTTPKISKTVLLSTKSMK 409

  Fly   507 RR---------------IRGKDKEEKVKPP---------------KPK----CRCGISGSSNTLT 537
            :.               |..|||..|.|.|               ||:    |:||.:..:.::.
  Rat   410 KSHEHGSKKSHSKSKPGILKKDKAVKEKIPSHHFMPGSPTKTVYKKPQEKKGCKCGRATQNPSVL 474

  Fly   538 TCRNSRCPCYKSYNSCAGCHCVCCKNPHKEDYVESDEDDDLEDFEMPKDVPE 589
            |||..|||||.:..:|..|.|..|:|    .|:.:.| ..||.|.:|:...|
  Rat   475 TCRGQRCPCYSNRKACLDCICRGCQN----SYMANGE-KKLEAFAVPEKALE 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
msl-2	NP_523467.1	zf-RING_10	39..111	CDD:293290	32/72 (44%)
		MSL2-CXC	520..567	CDD:293287	19/65 (29%)
Msl2	XP_236567.5	zf-RING_10	42..111	CDD:293290	32/72 (44%)
		MSL2_CXC	456..505	CDD:240555	18/52 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166341400
Domainoid	1	1.000	68	1.000	Domainoid score	I9518
eggNOG	1	0.900	-	-		E1_2CM0K
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG47806
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006426
OrthoInspector	1	1.000	-	-		oto95618
orthoMCL	1	0.900	-	-		OOG6_108363
Panther	1	1.100	-	-	LDO	PTHR16048
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	11	10.800