Protein Alignment msl-2 and msl2

DIOPT Version :9

• Sequence 1: NP_523467.1
• Gene: msl-2 / 33565
• FlyBaseID: FBgn0005616
• Length: 773
• Species: Drosophila melanogaster
• Sequence 2: XP_002939962.1
• Gene: msl2 / 100125142
• XenbaseID: XB-GENE-5773362
• Length: 580
• Species: Xenopus tropicalis
• Alignment Length: 665
• Identity: 151/665 - (22%)
• Similarity: 236/665 - (35%)
• Gaps: 223/665 - (33%)

  Fly     2 AQTAYLKVTRIAMR------SASNLSKRRVEELNSGLGELRQLLSCVVCCQLLVDPYSPKGKRCQ 60
            |...|:..:|:.:.      .||       .|:...|...||.|:|.||.:||.||.:|....||
 Frog     6 ATALYISASRLVLNYHPGDPQAS-------AEICKMLPYFRQALACCVCGKLLEDPIAPINSTCQ 63

  Fly    61 HNVCRLCLRGKKHLF-PSCTQCEGCSDFKTYEENRMMAAQLLCYKTLCVHLLHSALFGELAGMRP 124
            |.||:.| :|||.:. |||:.|:   |::.:|||:.::..:.|||.||.::..:.|
 Frog    64 HYVCKQC-KGKKMMMKPSCSWCK---DYEQFEENKQLSILVNCYKKLCEYITQTPL--------- 115

  Fly   125 QVARELVPRIKLPPKTTQEFIREGSNISDTFDI--FLPQPDLPFLKDMPTSLPAETPPTSAVTTP 187
              |::::                 :.:..:.||  |||                |.||
 Frog   116 --AQDIL-----------------NTVECSADILAFLP----------------EEPP------- 138

  Fly   188 ELPYDHHLNISDIEAEAAATAEQGHFSPLPL------LPTGSRMGMLSHAGQIVIATESSESGFM 246
                        :|.:..:|:|    .|.||      |||.|..|             |.....:
 Frog   139 ------------VEEKQESTSE----PPSPLCRSHSPLPTKSEHG-------------SEHEATI 174

  Fly   247 DQAWTDQVDLSGTVSVSKYTNSGNNFA-----VSYVMPTSATTKFDPQELQIGQV-VQMADSTQL 305
            .|...|:..:.....||....:.|..:     |:...|.|.:    |.:|....| ::..|.::
 Frog   175 CQLPQDRPSIEAECLVSNGLPNCNGLSETELPVNIPSPESPS----PMDLCCTAVDIKTEDLSE- 234

  Fly   306 AVLAAVEETVETSTQLTV----------------LSTTVEETVETSTQLEVLTSAEEPNEISDQL 354
             .|..|.:.|.||.....                |..:|||.:::   ||.::|.|..:  .|..
 Frog   235 -SLDTVCDPVSTSDLCAAGLDICGYNDDLKSGGPLLLSVEEVLQS---LETVSSTEVSD--CDLQ 293

  Fly   355 ANLQVEESDEALVEETVEEAEGTSIPSEVVAEHMEEDQHLDVHTSQSPTQTEMEEAVEEHVATKT 419
            .:|....|:.|.:|         ..|..:....:..|.|...|.....|.|
 Frog   294 HSLDTTASNGAFLE---------LCPQPLTHTVLLSDSHAPAHGISCTTAT-------------- 335

  Fly   420 QLGHVQTELQDAESLQKDFEDAKAAAEEAKEKEKDLHAISAELQKE-DSDEPTLKRKRTRT---- 479
             |..|:|..:            ::.:|...||...|...|..|... .|..|.|..:..|.
 Frog   336 -LKMVKTHRK------------RSRSESDSEKVLPLPISSIILGPTLGSPAPLLLTRENRNFLQP 387

  Fly   480 -----------------LKASQAAKIEPVPSEVKTKVQSGKGALRRIRGKDK-EEKV-------- 518
                             |.:::..|..|.....||. |..|.||  ::.||| :||:
 Frog   388 MATVPNGGSSPKISKTILLSNKNLKKNPEHGPKKTH-QKSKPAL--LKTKDKVKEKIPTNNVVPG 449

  Fly   519 --------KPPKPK-CRCGISGSSNTLTTCRNSRCPCYKSYNSCAGCHCVCCKNPHKEDYVESDE 574
                    ||.:.| |:||.:..:.::.|||..|||||.:..:|..|.|..|:|    .|:.:.|
 Frog   450 SPTKTVYKKPQEKKGCKCGRATQNPSVLTCRGQRCPCYSNRKACLDCICRGCQN----SYMANGE 510

  Fly   575 DDDLEDFEMPKDVPE 589
             ..||.|.:|:...|
 Frog   511 -KKLEAFAVPEKALE 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
msl-2	NP_523467.1	zf-RING_10	39..111	CDD:293290	31/72 (43%)
		MSL2-CXC	520..567	CDD:293287	18/47 (38%)
msl2	XP_002939962.1	zf-RING_10	42..111	CDD:374725	31/72 (43%)
		RING-HC finger (C3HC4-type)	44..84	CDD:319436	20/40 (50%)
		MSL2-CXC	458..512	CDD:374722	21/58 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	67	1.000	Domainoid score	I9719
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006426
OrthoInspector	1	1.000	-	-		oto102357
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4669
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.030