Protein Alignment Sec5 and sec5

DIOPT Version :10

• Sequence 1: NP_608780.1
• Gene: Sec5 / 33563
• FlyBaseID: FBgn0266670
• Length: 894
• Species: Drosophila melanogaster
• Sequence 2: NP_588182.1
• Gene: sec5 / 2539341
• PomBaseID: SPCC622.10C
• Length: 815
• Species: Schizosaccharomyces pombe
• Alignment Length: 897
• Identity: 171/897 - (19%)
• Similarity: 292/897 - (32%)
• Gaps: 242/897 - (26%)

  Fly    58 IARTGPAKGKGDIIVTTLSGGVGTSTVQFRAYHETIGPLKESAVWIEESPSQNFAWGRRTLAQSG 122
            |.|||.|..:    .|..:...|..|..|        .:|.|...::.|.|...|.|       |
pombe    53 ILRTGGATSE----TTKDASAAGPVTPSF--------AMKRSQTSVQPSMSSQIAIG-------G 98

  Fly   123 LTQEDPLGL-SIEGNEQKIPEDLRDLFPEACGDLSQE----HFSPAWFLLENHLATSFEDLKAGL 182
            :  .:|:.. .|.|..:..|::          .:.|.    |.|.:|...:            |.
pombe    99 M--RNPMATRKIAGTYRDAPDN----------SMQQTSTGVHRSSSWLTTD------------GT 139

  Fly   183 SYLKRKVESQKEGQLSFLKSNAGSVIDQLDTLMNIRDKLQEDVKLHG-NETLNILETSIENSISE 246
            ..|           ||.:::|....|...:|:.|:..::...:...| .:|:::.|.||..::.:
pombe   140 HQL-----------LSLMETNFNKFIAAKETIDNVYAQIISTLSHAGPAKTMDMCEESISGALQQ 193

  Fly   247 SQKIFTDVLVRKEKADSTRSVLFALSRHKFLFCLPNSVDRRAKAGEYDIVVNDYSRAKNLFGKTE 311
            .|...|:   ...:.|.:...|..:...:.||..|.......|..:|.:::.:...||.|:.|..
pombe   194 LQLFNTE---STNEVDISYGELLVMRECEALFTYPEKFRLYHKQEKYSLLMQEIENAKKLYEKDR 255

  Fly   312 IPIFR---KVLEEVDHRILSIRKQLHEKVVKMPQSVEQQKK----LIKALISLELQQSGTPIGDK 369
            ..:.:   |::..|||....|:..:......:...:.|.:.    :::.|..| |:....||..:
pombe   256 ERLAKVNPKLVYLVDHAWEIIQATIDGICASIWNQILQSQGDFAFVVRTLCDL-LKLKPNPISGR 319

  Fly   370 LRNIDPAWDAIEARAKYLEWTFRQTFDQHTSKDSGAQEKAKNRDSSQAPNRVNFCEELCDIAASQ 434
                ||...|..::.|||....::.|..........||              :|.:..|..|:..
pombe   320 ----DPVLYATVSQQKYLYNLMKERFSYFEKIIKSRQE--------------DFSKLSCTRASPM 366

  Fly   435 LPDLWRL----GQLYFTGELRGPHDPKPGDFKRMVLNAIEKFCVYLRLAILIATDQRALRQSSGL 495
            |  :||.    ..|.:|  |||    :|..|..|.|......||...:..:...:..|....||:
pombe   367 L--VWRAVARGCNLDYT--LRG----RPEVFAGMQLIEWANACVLKIVREIKEVELYAKEFISGI 423

  Fly   496 AWPIGSASATH------------QFLPWIPQCLRFTRIAYA---------------TLISLDLPS 533
            .......:|.|            :.|.  .|||   .:.|:               .||.|....
pombe   424 QQASYPEAAKHYGRDPKQMGVVVEKLN--SQCL---EMVYSFVGERGERLEMDGAFVLIQLHYFQ 483

  Fly   534 EALDIIQKLIDEVRLFCFSIIFKRATDRCKKLGSQETWELGVEEYPGATLLPAALETLLIETLDE 598
            ...|::.|.|        ..:|..|..||    ..:||.|  :..|.:.  .|.:|.:.|.
pombe   484 RVADLLPKRI--------RTVFSMAATRC----IVDTWML--QHAPQSK--SANIEEMFIV---- 528

  Fly   599 VQSVCMQRETREGNLLEPQSDGQREVTQRLQEFLSAFSAVIEELAFHSHDEE--TPTHNVSQLLG 661
                    :..|..:|||    :..|...|:|        :.:|....|.||  ...|:....:.
pombe   529 --------DANENQVLEP----ELMVVDVLRE--------LNKLYIPPHREEIVREIHHAFYKVL 573

  Fly   662 FPNAQQPDSVAGSGGAAAVTWEQRMLCCLANYAYCNKIFFPRLGDIFVRYGYPLPTLAIETARYT 726
            :.||:.|..........:..|.......:....:.|:....:|..   :....||..:....|..
pombe   574 YANARFPSMSVSMANWESDVWSLASSTLIDFVQHRNQHDMKKLAS---KMTTSLPVFSTSITRSD 635

  Fly   727 VNQLFT---NLLEEYVEHKGDPL----VGTIEPSMYLGRFQWDHEMEIGQLRPYAHECCDNLVGV 784
            |....|   ||....|.::...|    :..:.||                |.|...:...||..:
pombe   636 VLHFVTRLLNLRSRLVPYQKFLLQTFPLNEVSPS----------------LDPRISKSLRNLQDL 684

  Fly   785 YSEI------------YSISPALLRP---ILESIVQTISEELARLM-------------SC-VQR 820
            |..:            .|||...::|   .|.|.::||..||...|             || :.:
pombe   685 YKLLAIRDTSFSNTTPSSISKLSIQPPTFQLFSTLETIYLELKDSMPPNEAADWMIATTSCMLAQ 749

  Fly   821 FSFTGAIQAHVDIRLLRDSLEGYVNETAKNYFMEALEAINPPLSGEQKRKAD 872
            |:.........||    .|:..::|:......::.|:.|        :|||:
pombe   750 FALHSPYAFFHDI----PSISHFLNKCLPPTILDLLQQI--------QRKAE 789

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sec5	NP_608780.1	IPT_PCSR	5..85	CDD:238337	8/26 (31%)
		Sec5	126..889	CDD:464733	155/829 (19%)
sec5	NP_588182.1	Vps51	141..>353	CDD:480638	43/230 (19%)