Protein Alignment Sec5 and exoc2

DIOPT Version :10

• Sequence 1: NP_608780.1
• Gene: Sec5 / 33563
• FlyBaseID: FBgn0266670
• Length: 894
• Species: Drosophila melanogaster
• Sequence 2: NP_956898.1
• Gene: exoc2 / 100004870
• ZFINID: ZDB-GENE-040426-1160
• Length: 918
• Species: Danio rerio
• Alignment Length: 952
• Identity: 322/952 - (33%)
• Similarity: 506/952 - (53%)
• Gaps: 118/952 - (12%)

  Fly     5 PVVTGLSPKEGPPGTRVIIRGEFLGTRVQDLIGLKICGSDCLLSAEWKSPNKIIARTGPAK-GKG 68
            |:|||:||.||.|.|:|.||||.|||...|||||.|||.:|||:|||.|.:||:.|.|||| .||
Zfish     8 PLVTGISPNEGAPWTKVTIRGENLGTGPNDLIGLSICGHNCLLTAEWMSASKIVCRVGPAKDDKG 72

  Fly    69 DIIVTTLSGGVGTSTVQFRAYH-ETIGPLKESAVWIEESPSQNFAWGR-RTLAQSGLTQEDPLGL 131
            :|||||.|||.|||||.|:... |.||.|.:||||::|....:....| :.::...|...:|||:
Zfish    73 EIIVTTKSGGRGTSTVSFKLLKPERIGILDQSAVWVDELNYYDMRTDRNKGISPLSLRPANPLGI 137

  Fly   132 SIEGNEQKIP-EDLRDLFPEACGDLSQEHFSPAWFLLENHLATSFEDLKAGLSYLKRKVESQKEG 195
            .|:  ..|:| :||.::||...||.:.|:||..|:|:|||.:||||.|:||:..||::...:.||
Zfish   138 DID--RGKVPLKDLENMFPGMSGDFTSENFSATWYLIENHSSTSFEHLRAGVGNLKKQASKKNEG 200

  Fly   196 QLSFLKSNAGSVIDQLDTLMNIRDKLQED--VKLHGNETLNILETSIENSISESQKIFTDVLVRK 258
            .|:::|....:..:..|.|..|..||:.|  .|:.|:.|.. |||.:..:...:..:|.:||.||
Zfish   201 SLAYVKGGLSTFFEAQDALAAIHQKLESDGTEKVEGSMTQR-LETILNRASETADTLFQEVLGRK 264

  Fly   259 EKADSTRSVLFALSRHKFLFCLPNSVDRRAKAGEYDIVVNDYSRAKNLFGKTEIPIFRKVLEEVD 323
            :||||||:.|..|.|.||||.||.:::|..:.|:||:|:|||.:||:|||.||:|:|:||..||:
Zfish   265 DKADSTRNALNVLQRFKFLFNLPLNIERNIQKGDYDVVINDYEKAKSLFGNTEVPVFKKVYSEVE 329

  Fly   324 HRILSIRKQLHEKVVKMPQSVEQQKKLIKALISLELQQSGTPIGDKLRNIDPAWDAIEARAKYLE 388
            .||.::||.|.:|:::.|.::..||:.|:.|  .:|...|          ||||..|.|:.|
Zfish   330 TRIEALRKLLLDKLLETPSTLHDQKRYIRYL--SDLHAPG----------DPAWQCIIAQHK--- 379

  Fly   389 WTFRQTFDQHTSKDSGAQEKAKN-----------------------------RDSS---QAPNRV 421
            |..:  ..|:..:|...::|...                             :|.|   ::|.:|
Zfish   380 WILQ--LMQNCKEDFIKEQKVGGVGLDLDRSSVLNRISLSAPVKRGGSFQTPKDDSWHYKSPQQV 442

  Fly   422 NFCEELCDIAASQLPDLWRLGQLYFTGELRGPHDPKPG--------------DFKRMVLNAIEKF 472
            .|.|:|.|:..||||:.|:|...|..|.|......|.|              |||.|:.....:.
Zfish   443 RFVEKLSDVVISQLPNFWKLWISYVNGSLFSETGEKSGQVEKLKKNARQRQNDFKGMIEEVTRRL 507

  Fly   473 CVYLRLAILIAT-DQRALRQSSGLAW----PIGSASATHQFLPWIPQCLRFTRIAYATLISLDLP 532
            ...:|.|:|.:: .:..|||..|  |    |:..|        |:.|.:...|:::..|.:|::|
Zfish   508 VQLVRGALLPSSLTELQLRQYGG--WDTKTPLTGA--------WLTQVIHTVRLSHEALSALEIP 562

  Fly   533 SEALDIIQKLIDEVRLFCFSIIFKRATDRCKKLGSQETWELGVEEYPGATLLPAALETLLIETLD 597
            ::.|.:||.|:.::|:.|.....:...:..|:|..:|.|   |.:..|.|.|||..|..:::.|
Zfish   563 NDLLQVIQDLLQDLRVHCLLTTLQHTEEDVKRLAEKEDW---VVDNEGITSLPAQFEQCMVQML- 623

  Fly   598 EVQSVCMQRETREGNLLEPQSD-GQREVTQRLQEFLSAFSAVIEELAFHSHDEETPTHNVSQLLG 661
              ||:....|.:.|.:.....| .|.:..::....:..|...:|:|:..: ||:..|.::|..|.
Zfish   624 --QSLKEPMECKPGEINISNLDVVQDKACEQCVSIMKVFIKCLEQLSTKT-DEDINTSHLSVDLT 685

  Fly   662 FPN---------AQQPDSVAGSGGAAAVTWEQRMLCCLANYAYCNKIFFPRLGDIFVRYGYPLPT 717
            .|:         :.:|              |||:|..|:|..|..:..|..|.:...:.|:.:..
Zfish   686 SPDLFGSIKEDFSSKP--------------EQRLLIILSNCQYLERHTFLNLAEHLEKNGFTMAD 736

  Fly   718 LAIETARYTVNQLFTNLLEEYVEHKGDPLVGTIEPSMYLGRFQWDHEMEIGQLRPYAHECCDNLV 782
            ..|..:...:.||..:|.|.|:|.|.||:||::|..:|.|.|.|...:....:|.|..|...:::
Zfish   737 KIIRVSIDALRQLDYDLFEMYIEKKSDPIVGSLETGIYAGYFDWKDCLLPTGVRSYLKEALVSII 801

  Fly   783 GVYSEIYSISPALLRPILESIVQTISEELARLMSCVQRFSFTGAIQAHVDIRLLRDSLEGYVNET 847
            .|::|::::|..|:..:|..|::.::||::|||.||..||..||:||.::|..|||::|.|::..
Zfish   802 SVHAEVFTVSKELVSRVLSKIIEAVAEEMSRLMQCVSSFSKNGALQARLEICALRDAIEPYLSSE 866

  Fly   848 AKNYFMEALEAINPPLSGEQKRKADEILERVKRNMRLQLLCF 889
            :...|.:||||:....||..|:..:|:|.:.|.:|:|||.||
Zfish   867 SCTSFKQALEALPQLQSGADKKLLEELLNKFKSSMKLQLNCF 908

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sec5	NP_608780.1	IPT_PCSR	5..85	CDD:238337	54/80 (68%)
		Sec5	126..889	CDD:464733	253/826 (31%)
exoc2	NP_956898.1	TIG	8..91	CDD:460355	55/82 (67%)
		Sec5	132..908	CDD:464733	253/826 (31%)