Protein Alignment Cog3 and Cog3

DIOPT Version :10

• Sequence 1: NP_608779.1
• Gene: Cog3 / 33562
• FlyBaseID: FBgn0031536
• Length: 905
• Species: Drosophila melanogaster
• Sequence 2: XP_063130504.1
• Gene: Cog3 / 361073
• RGDID: 1304555
• Length: 930
• Species: Rattus norvegicus
• Alignment Length: 834
• Identity: 360/834 - (43%)
• Similarity: 508/834 - (60%)
• Gaps: 56/834 - (6%)

  Fly    15 RKIRNRLMQWESKTDPLAALSIQQE----------EHLDVLTNLWRDSGPSAPAPTTPTQVGPTD 69
            |..|.:|..|:.:.|.:|.|:.:|.          |:|.|...|..:...|..:.:.|.::
  Rat    82 RDAREKLSLWDRRPDSIAPLTDRQTDSVLELKAAVENLPVPAELPIEDVCSLASQSLPIEL---- 142

  Fly    70 SSAAATSQSGDDIRLPA--------EGLQNTNEFLLWFADVSAEIEQRGDADYHKYLQQLEQRKA 126
              .|...:|.:|:.|..        |.::...:|..|||.:..:::|.....|.:....|...:.
  Rat   143 --TAVVPESTEDVLLKGFTSLGMEEERIETAQQFFSWFAKLQTQMDQDEGTKYRQMRDYLSGFQE 205

  Fly   127 ECSHMLDQIAGAMERLGALCDEYDFVSQKTSALNTASEQLIEEQERLQELSHEIQRRLHYFSQVE 191
            :|..:|..:..|::.|.:|..:|.|||.||..|:.|.|||::||..|.:|:..||::|.||:::|
  Rat   206 QCDAILSDVNSALQHLESLQKQYLFVSNKTGTLHEACEQLLKEQSELADLAEHIQQKLSYFNELE 270

  Fly   192 LLNQRLQSPTLSVASEAFRECLNKIDECLNYIEENPKFKDAAAYNVKYRQCLAKASGLVRNYVTS 256
            .:|.:|.||||||.||.|...|.|:|:|:.||..:|.|||...|.:|::|||:||..|::.|..:
  Rat   271 TINTKLNSPTLSVNSEGFIPMLAKLDDCITYISSHPNFKDYPVYLLKFKQCLSKALHLMKTYTVN 335

  Fly   257 VINQATEATL-HPKNNMPDASAALKAPDAAFALYYGKYQTAAAKVKRVAQLIESRSEHSLDYAQL 320
            .:...|...| ...:::|:|       |.||.|:|.|::.||.||:.:.:.||.|||...:|..|
  Rat   336 TLQTLTNQLLKRDPSSVPNA-------DNAFTLFYVKFRAAAPKVRTLIEQIEQRSEKIPEYQHL 393

  Fly   321 MADLQQHYLAQRASVMSPAVNLSIQNVKVAHKGDHCSLTRSACAFLVHVCQDEQRLFYQFFSTGA 385
            :.|:.|.||.||..::.|::..::..:...:..|||:|.||.|||:|||||||.:|:.:||:...
  Rat   394 LNDIHQCYLDQRELLLGPSIAYTVTELTSQNNRDHCALVRSGCAFMVHVCQDEHQLYNEFFTKPT 458

  Fly   386 PHLTVYLEGLCTILYDTMRPFIIHINHLETLAEICSILRIEMLEEHVQQNPVALEAFATIAHQLL 450
            ..|...||.||..|||..||.|||:.|||||:|:|.||:.|:||:|||.|...|.|||....|:|
  Rat   459 SKLDELLEKLCVSLYDVFRPLIIHVIHLETLSELCGILKNEVLEDHVQNNAEQLGAFAAGVKQML 523

  Fly   451 QDVQERLVFRAHLYLQSDIQNFNPSSGDLAYPEKLEMMESIALSLQE-----PAPLRRSDSR--N 508
            :|||||||:|.|:|:|:||..:.|:.||||||:||.|||.||.||::     |:....||.|  .
  Rat   524 EDVQERLVYRTHIYIQTDITGYKPAPGDLAYPDKLVMMEQIAQSLKDEQKKTPSEASFSDVRLEE 588

  Fly   509 SMVSSVSSAVETESV--ATAYTVKQMNSPADLHGMWYPTVRRTLVCLSRLYRCVDRPIFQGLSQE 571
            ...||:..:..|:|:  ....|:    |||||||||||||||||||||:||||:||.:|||||||
  Rat   589 GESSSLRKSGSTDSLNPRPQTTI----SPADLHGMWYPTVRRTLVCLSKLYRCIDRAVFQGLSQE 649

  Fly   572 ALKLCIQSVSHAAGKISANKTPIDGELFEIKHLLILREQIAPFRVDFTVKETSLDFSKVKTAAFG 636
            ||..||||:..|:..||.|||.|||:||.||||||||||||||..:||:||.|||..|.:.|||.
  Rat   650 ALSACIQSLLGASESISKNKTQIDGQLFLIKHLLILREQIAPFHTEFTIKEISLDLKKTRDAAFK 714

  Fly   637 LLQKR--KQLFSMGSNNALLEFLLEGTPQIKEHLLDSRKEVDRQLKSVCEKYIKDAVQMLVGPLI 699
            :|...  .:.|.:.|||||:||||||||:|:||.|||:|:|||.|||.||::|:...::.|.||.
  Rat   715 ILNPMTVPRFFRLNSNNALIEFLLEGTPEIREHYLDSKKDVDRHLKSACEQFIQQQTRLFVEPLE 779

  Fly   700 TFLEKAQSLLAQSTPATPQSPESTKASYVLRQSPWASPQQISSIIQETQRLIKAKLAVLQRSMQL 764
            .|:.|..:|...::...|:        |.|.|.|||.|.:::.::....:.||.||....|||.|
  Rat   780 EFMTKVSALKTMASQGGPK--------YTLSQQPWAQPAKVNDLVATAYKTIKTKLPQTLRSMSL 836

  Fly   765 YLSNRDTEFIIFRPIRNNIIQSFVKLEQLLTTNGYSTDDMIITSCPSAEQVSIL 818
            ||||:|||||:|:|:||||.|.|.|...||... :|.:|:.|.:|||.|||.::
  Rat   837 YLSNKDTEFILFKPVRNNIQQVFQKFHALLKEE-FSPEDIQIIACPSVEQVRLV 889

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cog3	NP_608779.1	Sec34	117..261	CDD:461190	57/143 (40%)
Cog3	XP_063130504.1	None