Protein Alignment Cog3 and cog3

DIOPT Version :10

• Sequence 1: NP_608779.1
• Gene: Cog3 / 33562
• FlyBaseID: FBgn0031536
• Length: 905
• Species: Drosophila melanogaster
• Sequence 2: XP_002941013.3
• Gene: cog3 / 100497861
• XenbaseID: XB-GENE-855843
• Length: 821
• Species: Xenopus tropicalis
• Alignment Length: 840
• Identity: 369/840 - (43%)
• Similarity: 520/840 - (61%)
• Gaps: 53/840 - (6%)

  Fly     8 QSENENLRKIRNRLMQWESKTDPLAALSIQQEEHLDVLTNLWRDSGPSAPAP----TTPTQVGPT 68
            |.|.|    .|:||..|:...||||.|:.:|.:.:..:.....|....|..|    .:.|....|
 Frog     5 QEEQE----ARDRLALWDRGPDPLALLTDRQTDSILEIKAAAEDLPVPAELPIEDLCSLTSRSLT 65

  Fly    69 DSSAAATSQSGDDI--------RLPAEGLQNTNEFLLWFADVSAEIEQRGDADYHKYLQQLEQRK 125
            .:.:||..:|.:||        .:..:.::...:|..||..:...::..|.|.|.:....|...:
 Frog    66 VTLSAAVPESTEDILKQGFSMLGMEEDRIETAQQFFSWFDKLQIHMDHDGSAKYREMRDFLAGFQ 130

  Fly   126 AECSHMLDQIAGAMERLGALCDEYDFVSQKTSALNTASEQLIEEQERLQELSHEIQRRLHYFSQV 190
            .:|..:|:.:..|:|.|.:|..:|.|||.||..|:.|.|||::||....:|:..||::|.||:::
 Frog   131 EQCDAILNDVNVALEHLESLQKQYLFVSTKTGTLHEACEQLLKEQSEFVQLAENIQQKLSYFNEL 195

  Fly   191 ELLNQRLQSPTLSVASEAFRECLNKIDECLNYIEENPKFKDAAAYNVKYRQCLAKASGLVRNYVT 255
            |.:|.:|.||||||.||.|...|.|:|:|:.||..:|.:||...|..|::|||.||..|::||..
 Frog   196 ETINTKLNSPTLSVNSEGFIPMLTKLDDCITYISAHPNYKDYPVYMAKFKQCLYKAMHLMKNYTV 260

  Fly   256 SVINQATEATLHPKNNMPDASAALKAPDAAFALYYGKYQTAAAKVKRVAQLIESRSEHSLDYAQL 320
            :.:...|...:  |.:..:||..    |.||.|:|.|::.||.||:.:.:.:|.|||...:|.||
 Frog   261 NTMQNLTSQLI--KRDSSNASTT----DNAFTLFYVKFRAAAPKVRTLIEQVEQRSEKIPEYQQL 319

  Fly   321 MADLQQHYLAQRASVMSPAVNLSIQNVKVAHKGDHCSLTRSACAFLVHVCQDEQRLFYQFFSTGA 385
            ::::.|.||.||.|::||::..:|.::...:..|||:|.||.|||:|||||||..|:.:||:...
 Frog   320 LSEIHQCYLDQRESLLSPSITTTITDLTSQNNRDHCALVRSGCAFMVHVCQDEHHLYNEFFTKPT 384

  Fly   386 PHLTVYLEGLCTILYDTMRPFIIHINHLETLAEICSILRIEMLEEHVQQNPVALEAFATIAHQLL 450
            |.|.|.||.||..|||..||.|||:.|||||:|:|.||:|||||:|||.:...|.|||.:..|:|
 Frog   385 PKLDVLLEKLCLSLYDVFRPLIIHVVHLETLSELCGILKIEMLEDHVQNSVEHLGAFAAVVKQML 449

  Fly   451 QDVQERLVFRAHLYLQSDIQNFNPSSGDLAYPEKLEMMESIALSLQE-------------PAPLR 502
            :|||||||:|.|:|:||||..:.|:.||||||:||||||.||.|::|             ...|.
 Frog   450 EDVQERLVYRTHIYIQSDILGYKPAPGDLAYPDKLEMMEKIAQSIKEEQQRLHSTESSFSDVHLE 514

  Fly   503 RSDSRNSMVSSVSSAVETESVATAYTVKQMNSPADLHGMWYPTVRRTLVCLSRLYRCVDRPIFQG 567
            ..||.|.:.|..|.::..:...|.       |||||||||||||||||||||:||||:||.:|||
 Frog   515 DPDSNNLIKSGASESLSQKPQNTV-------SPADLHGMWYPTVRRTLVCLSKLYRCIDRAVFQG 572

  Fly   568 LSQEALKLCIQSVSHAAGKISANKTPIDGELFEIKHLLILREQIAPFRVDFTVKETSLDFSKVKT 632
            ||||||..||||:..|:..|:.|||.|||:||.||||||||||||||..:||:||.|||..|.:.
 Frog   573 LSQEALSACIQSLLGASEAITKNKTQIDGQLFLIKHLLILREQIAPFHTEFTIKEISLDLKKTRD 637

  Fly   633 AAFGLLQKR--KQLFSMGSNNALLEFLLEGTPQIKEHLLDSRKEVDRQLKSVCEKYIKDAVQMLV 695
            |||.:|..|  .:.|.:.||||||||||:|||:||||.:||:|:|||.||:.||::|:...::.|
 Frog   638 AAFKILHPRTVPRFFRLNSNNALLEFLLQGTPEIKEHFIDSKKDVDRHLKAACEQFIQQQSKIFV 702

  Fly   696 GPLITFLEKAQSLLAQSTPATPQSPESTKASYVLRQSPWASPQQISSIIQETQRLIKAKLAVLQR 760
            .||..|:.|..:|...::...|:        |.|.|.|||.|.:|:.::..|.:.:|.||.|..|
 Frog   703 EPLEDFMTKVTALKTMASQGGPK--------YSLSQQPWAQPVKINDLVSSTYKTMKTKLPVTLR 759

  Fly   761 SMQLYLSNRDTEFIIFRPIRNNIIQSFVKLEQLLTTNGYSTDDMIITSCPSAEQVSILLS 820
            .|.|||:|:|||||:|:|:|:||.|.|.|:..||... ::::|:.|.:|||.|||::|||
 Frog   760 GMSLYLANKDTEFILFKPVRSNIQQVFQKIHMLLKEE-FASEDLQIIACPSMEQVNLLLS 818

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cog3	NP_608779.1	Sec34	117..261	CDD:461190	57/143 (40%)
cog3	XP_002941013.3	Sec34	123..266	CDD:461190	57/142 (40%)