DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12795 and CUZ1

DIOPT Version :9

Sequence 1:	NP_001097074.1	Gene:	CG12795 / 33561	FlyBaseID:	FBgn0031535	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	NP_014244.1	Gene:	CUZ1 / 855567	SGDID:	S000005099	Length:	274	Species:	Saccharomyces cerevisiae

Alignment Length:	227	Identity:	46/227 - (20%)
Similarity:	84/227 - (37%)	Gaps:	52/227 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LGQHCSEATCNRLDFLPVKCDSCDKVFCASHYSYDRHSCPGAYKKNVQVPVCPLCREPVPTPPGV 70
            :|:||  |.|.:|||||..|..|::.||::|...:.|.|....:.
Yeast    14 VGKHC--AYCRQLDFLPFHCSFCNEDFCSNHRLKEDHHCRWLLEH-------------------- 56

  Fly    71 EPDVTVGQHIDQQCKSESKKIYTNRCNAKGCKRKELIPVTCSQCRLNFCLRHRHTSDHDCKPVPA 135
                   :.:.:..||.||....:..|.: ...|.|:|...|       :|.:..|: ..:|:..
Yeast    57 -------EEVHKTEKSPSKSRDGSSSNDE-AYFKSLLPERAS-------VRIQRVSE-TREPLRG 105

  Fly   136 SSTTSSRGGFQSIFKTSSDSRSMAAQAAERRQNRRPASNSISNTNSRPRPVQATQVQNIQGNMSE 200
            |:|........|  ||.........:..:|:.|.:...|..|::|      :..|:.|::.....
Yeast   106 SNTAKVSSTLNS--KTLDKIFKFFQRNEKRKSNNKSKKNFGSSSN------KIIQLANLKKIAKG 162

  Fly   201 DEALARALALSIM------EQDDAAESNRQAP 226
            |..:.....:.|.      ::.|.|:.:.:.|
Yeast   163 DPKIPMQNRIYIWCYLVDGDETDIAKEDTRMP 194

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12795	NP_001097074.1	zf-AN1	10..46	CDD:279736	15/35 (43%)
CG12795	NP_001097074.1	zf-AN1	96..131	CDD:279736	7/34 (21%)
CUZ1	NP_014244.1	ZnF_AN1	18..55	CDD:197545	15/38 (39%)
CUZ1	NP_014244.1	COG3582	90..274	CDD:226110	21/121 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3183
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S2130
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002265
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR14677
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.820