DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12795 and ZFAND2B

DIOPT Version :9

Sequence 1:	NP_001097074.1	Gene:	CG12795 / 33561	FlyBaseID:	FBgn0031535	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	XP_006712348.1	Gene:	ZFAND2B / 130617	HGNCID:	25206	Length:	338	Species:	Homo sapiens

Alignment Length:	244	Identity:	105/244 - (43%)
Similarity:	142/244 - (58%)	Gaps:	34/244 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MEFPHLGQHCSEATCNRLDFLPVKCDSCDKVFCASHYSYDRHSCPGAYKKNVQVPVCPLCREPVP 65
            ||||.||.||||.:|.||||||:|||:|..:|||.|.:|.:|.|..||:|::||||||||..|||
Human     1 MEFPDLGAHCSEPSCQRLDFLPLKCDACSGIFCADHVAYAQHHCGSAYQKDIQVPVCPLCNVPVP 65

  Fly    66 TPPGVEPDVTVGQHIDQQCKS----ESKKIYTNRCNAKGCKRKELIPVTCSQCRLNFCLRHRHTS 126
            ...|..||..||:|||:.|:|    :.:||:||:|...||:::|::.:||.:|..|||::|||..
Human    66 VARGEPPDRAVGEHIDRDCRSDPAQQKRKIFTNKCERAGCRQREMMKLTCERCSRNFCIKHRHPL 130

  Fly   127 DHDCKPVPASSTTSSRGGF------QSIFKTS---SDSRSMAAQAAERRQNRRPASNSISNTNSR 182
            ||||.   .....:||.|.      |::..||   |.|::|            |:..|.|...:|
Human   131 DHDCS---GEGHPTSRAGLAAISRAQAVASTSTVPSPSQTM------------PSCTSPSRATTR 180

  Fly   183 PRPVQATQVQNIQGNMSEDEALARALALSIMEQDDAAESNRQAPAPSNA 231
            .....|..|..:|..:||||||.|||.:|:      ||:..|.|.|..|
Human   181 SPSWTAPPVIALQNGLSEDEALQRALEMSL------AETKPQVPRPRAA 223

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12795	NP_001097074.1	zf-AN1	10..46	CDD:279736	21/35 (60%)
CG12795	NP_001097074.1	zf-AN1	96..131	CDD:279736	16/34 (47%)
ZFAND2B	XP_006712348.1	zf-AN1	10..46	CDD:279736	21/35 (60%)
		zf-AN1	100..136	CDD:279736	17/38 (45%)
		UIM	197..212	CDD:280900	10/20 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165154593
Domainoid	1	1.000	62	1.000	Domainoid score	I10426
eggNOG	1	0.900	-	-		E1_KOG3183
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H32671
Inparanoid	1	1.050	206	1.000	Inparanoid score	I3721
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1422113at2759
OrthoFinder	1	1.000	-	-		FOG0002265
OrthoInspector	1	1.000	-	-		otm41137
orthoMCL	1	0.900	-	-		OOG6_102690
Panther	1	1.100	-	-	LDO	PTHR14677
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4414
SonicParanoid	1	1.000	-	-		X1690
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.790