DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12795 and zfand2b

DIOPT Version :9

Sequence 1:	NP_001097074.1	Gene:	CG12795 / 33561	FlyBaseID:	FBgn0031535	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	XP_004917699.1	Gene:	zfand2b / 100487091	XenbaseID:	XB-GENE-5994975	Length:	266	Species:	Xenopus tropicalis

Alignment Length:	274	Identity:	112/274 - (40%)
Similarity:	155/274 - (56%)	Gaps:	29/274 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MEFPHLGQHCSEATCNRLDFLPVKCDSCDKVFCASHYSYDRHSCPGAYKKNVQVPVCPLCREPVP 65
            ||||.||:||||.||.:|||||:|||:|:::||..|.:|.:|.|..||||:|||||||||..|:|
Frog     1 MEFPDLGKHCSETTCKQLDFLPLKCDACEQIFCKDHITYTQHKCSSAYKKDVQVPVCPLCNTPIP 65

  Fly    66 TPPGVEPDVTVGQHIDQQCKS----ESKKIYTNRCNAKGCKRKELIPVTCSQCRLNFCLRHRHTS 126
            ...|..||:.||:|||:.|||    :.:||:||:|...||::|||:.|.|..|..||||:|||..
Frog    66 ITRGQTPDIVVGEHIDRDCKSDPARQKRKIFTNKCAKPGCRQKELMKVICEDCHGNFCLKHRHPL 130

  Fly   127 DHDCKPVPASSTTSSRGGFQSIFKTSSDSRSMAAQAAERRQNRRPASNSISNTNSRP--RPVQAT 189
            ||:||   ..|...||.|..::.:  |...:..|.|.......|||:.......|.|  :|..|.
Frog   131 DHECK---GKSAPISRAGHAALLR--SQPSTSKASAPSSHAAPRPATQPPRIRTSVPSAQPPAAA 190

  Fly   190 QVQNIQGNMSEDEALARALALSIMEQDDAAESNRQAPAPSNAQQVAVGGGGNQ-----------Q 243
            .:||   .::|:|||.|||.:|:.|...||.:..|:.:....:.:|:....:.           |
Frog   191 SLQN---GLTEEEALQRALEMSLAESSGAAAAAAQSHSSQEEEDLALARALSASEEEYRRQQAIQ 252

  Fly   244 GNGKD----KCLLS 253
            |..:|    .|.||
Frog   253 GQNRDAKQSMCSLS 266

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12795	NP_001097074.1	zf-AN1	10..46	CDD:279736	20/35 (57%)
CG12795	NP_001097074.1	zf-AN1	96..131	CDD:279736	18/34 (53%)
zfand2b	XP_004917699.1	zf-AN1	10..46	CDD:376545	20/35 (57%)
		P-loop_NTPase	<69..116	CDD:393306	22/46 (48%)
		zf-AN1	100..136	CDD:376545	20/38 (53%)
		rad23	<137..>208	CDD:273167	23/75 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	66	1.000	Domainoid score	I9846
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H32671
Inparanoid	1	1.050	197	1.000	Inparanoid score	I3696
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1422113at2759
OrthoFinder	1	1.000	-	-		FOG0002265
OrthoInspector	1	1.000	-	-		oto103471
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1690
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.060