Protein Alignment Snx1 and snx2

DIOPT Version :10

• Sequence 1: NP_608777.1
• Gene: Snx1 / 33560
• FlyBaseID: FBgn0031534
• Length: 458
• Species: Drosophila melanogaster
• Sequence 2: NP_001032787.1
• Gene: snx2 / 568737
• ZFINID: ZDB-GENE-051120-45
• Length: 506
• Species: Danio rerio
• Alignment Length: 490
• Identity: 215/490 - (43%)
• Similarity: 307/490 - (62%)
• Gaps: 51/490 - (10%)

  Fly     3 VESPEHTRDFAEVDINNGAATGSEDEEEEVPAPGSVTLDRNESDLFVSA---------------- 51
            :||||.....:||     |:|||...:.|     .:.||.:..|||..|
Zfish    32 MESPEDLHVPSEV-----ASTGSNGPKAE-----QILLDDDTEDLFAEATEEVSLDSPERQPILS 86

  Fly    52 ---------LSPSSIG---DIHPLQEVLTDDGD-------YFISIVVSDPQKIGDGMGSYLAYKV 97
                     ::|.|||   ::........:|.|       ..|.|.||||:|:||||.:|:.|||
Zfish    87 DGPSPAITPVTPVSIGSRVELGAFDRSPEEDEDEQESRDTLDIQISVSDPEKVGDGMNAYMVYKV 151

  Fly    98 TTKTNIPKFKRSEFSTLRRFSDFLGIHDLLVGKYMRLGRIIPPAPSKNIIGSTKVKISPQQSEPG 162
            |||:.:..|.|||....||||||||:|..|..||:.:|.|:||||.|:|:|.||||:..:...
Zfish   152 TTKSCLSVFSRSEVCVRRRFSDFLGLHSKLASKYLHVGLIVPPAPEKSIVGMTKVKVGKEDLS-- 214

  Fly   163 TPMTQEWVEIRRAALERFVHRTAQHPVLRVDLDFMNFLESDQELPRSVNTSALSGAGVIRLFNKV 227
               :.|:||.||:||||::.||.:||.|..|.|.:.|||| .||||:|:|.||||||::|:.||.
Zfish   215 ---SVEFVEKRRSALERYLMRTVKHPALLKDPDVLQFLES-SELPRAVSTQALSGAGILRMVNKA 275

  Fly   228 GETVNKITYKMDENDPWFDDKITEVESLDANLQKLHNAMKSLVTSRRELSLLTGLVAKSAAMLST 292
            .:.|||:|.||:|.|.||::|..:.|:||..|:|||.:::|||..|:|||:.|.|.|||||||..
Zfish   276 ADAVNKMTIKMNEADAWFEEKQQQFENLDLQLRKLHASVESLVCHRKELSVNTALFAKSAAMLGN 340

  Fly   293 CEEHTGLSRALSNLADVEEKIELLRSEQANSDFFILAEFIKDYLGLFGAIKCIFHERVKAFQNWQ 357
            .|:||.||||||.||:||||::.:..:||.:||::.:|.:.||:.|..|::.:|.:|:|.:..||
Zfish   341 SEDHTALSRALSQLAEVEEKMDQMHQDQAYADFYLFSELLGDYVRLITAVRGVFDQRMKTWAKWQ 405

  Fly   358 YAQMQLSKRRENRGRFELANRADKLDQAQQEVDEWQGKVQRCQQQFDDISAEIKREMERFELTRV 422
            .||:.|.::||...:.:.||:.|||.||:.|:.||:||||:.::.|:.||..|:||:.|||..||
Zfish   406 DAQVMLQRKREAEAKLQYANKPDKLQQAKDEIKEWEGKVQQGERDFEQISKNIRREVGRFEKDRV 470

  Fly   423 KDFKVNIIKYIEDQMAHQQQIVSYWEAFAPFAREI 457
            |||::.::||:|..:..|||::.|||||.|.|:.|
Zfish   471 KDFRIVVVKYLESLVHTQQQLIKYWEAFLPEAKAI 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Snx1	NP_608777.1	PX_SNX1_2_like	75..203	CDD:132769	66/127 (52%)
		BAR_SNX1_2	232..455	CDD:153307	107/222 (48%)
snx2	NP_001032787.1	Sorting_nexin	3..68	CDD:461016	15/45 (33%)
		PX_SNX2	129..252	CDD:132815	67/128 (52%)
		BAR_SNX2	270..503	CDD:153348	111/232 (48%)