Protein Alignment Snx1 and SNX30

DIOPT Version :10

• Sequence 1: NP_608777.1
• Gene: Snx1 / 33560
• FlyBaseID: FBgn0031534
• Length: 458
• Species: Drosophila melanogaster
• Sequence 2: XP_047279349.1
• Gene: SNX30 / 401548
• HGNCID: 23685
• Length: 443
• Species: Homo sapiens
• Alignment Length: 472
• Identity: 112/472 - (23%)
• Similarity: 197/472 - (41%)
• Gaps: 122/472 - (25%)

  Fly     5 SPE--HTRDFAEVDI---NNGAATGSEDEEEEVPAPGSVTLDRNESDLFVSALSPSSIGDIHPLQ 64
            ||:  ..|.|.:.|:   |.|...|:..     ||..|..|:|.:.|           .||
Human    40 SPDLLMARSFGDKDLILPNGGTPAGTSS-----PASSSSLLNRLQLD-----------DDI---- 84

  Fly    65 EVLTDDG---DYFISIVVSDPQKIGDGMGSYLAYKVTTKTNIPKFKRSEFSTLRRFSDFLGIHDL 126
                 ||   |.|  ::|.||:|....|.:|:.|::|||:...:|...|:|..||:.||    |.
Human    85 -----DGETRDLF--VIVDDPKKHVCTMETYITYRITTKSTRVEFDLPEYSVRRRYQDF----DW 138

  Fly   127 LVGKY--MRLGRIIPPAPSKNIIGSTKVKISPQQSEPGTPMTQEWVEIRRAALERFVHRTAQHPV 189
            |..|.  .:...:|||.|.|.::.....:.|           :|:||.||.||::|:.|...|||
Human   139 LRSKLEESQPTHLIPPLPEKFVVKGVVDRFS-----------EEFVETRRKALDKFLKRITDHPV 192

  Fly   190 LRVDLDFMNFLESDQELPRSVNTSALSGAGVIRLFNKVGETVNKIT--YKMDEN-------DPWF 245
            |..:..|..||.:     :.:|.....|   |.|..::||:|..:|  ||:...       ..:.
Human   193 LSFNEHFNIFLTA-----KDLNAYKKQG---IALLTRMGESVKHVTGGYKLRTRPLEFAAIGDYL 249

  Fly   246 DDKITEVESLDANLQKLHNAMKSLVTSRREL-------SLLTGLVAKSAAMLSTCEEHTGLSRAL 303
            |....::.::|...|::.......:...||.       |.|.|.:|:....:|.|..:  .|.||
Human   250 DTFALKLGTIDRIAQRIIKEEIEYLVELREYGPVYSTWSALEGELAEPLEGVSACIGN--CSTAL 312

  Fly   304 SNLAD--VEEKIELLRSEQANSDFFILAEFIKDYLGLFGAIKCIFHERVKAFQNWQYAQMQLSKR 366
            ..|.|  .|:.:.:||      ::.:.::.:|..|.....::..:..:::|          ::.|
Human   313 EELTDDMTEDFLPVLR------EYILYSDSMKSVLKKRDQVQAEYEAKLEA----------VALR 361

  Fly   367 RENRGRFELANRADKLDQAQQEVDEWQGKVQRCQQQFDDISAEIKREMERFELTRVKDFKVNIIK 431
            :|:|.:..    ||               |::||.:.:..:|::|.:|||::..:.:||:..:
Human   362 KEDRPKVP----AD---------------VEKCQDRMECFNADLKADMERWQNNKRQDFRQLL-- 405

  Fly   432 YIEDQMAHQQQIVSYWE 448
                 |....:.:.|:|
Human   406 -----MGMADKNIQYYE 417

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Snx1	NP_608777.1	PX_SNX1_2_like	75..203	CDD:132769	42/129 (33%)
		BAR_SNX1_2	232..455	CDD:153307	43/235 (18%)
SNX30	XP_047279349.1	PX_SNX7_30_like	91..206	CDD:132770	43/136 (32%)
		BAR_SNX30	190..418	CDD:153351	57/280 (20%)