DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Snx1 and Snx30

DIOPT Version :9

Sequence 1:	NP_608777.1	Gene:	Snx1 / 33560	FlyBaseID:	FBgn0031534	Length:	458	Species:	Drosophila melanogaster
Sequence 2:	XP_038965375.1	Gene:	Snx30 / 298033	RGDID:	1311367	Length:	456	Species:	Rattus norvegicus

Alignment Length:	469	Identity:	112/469 - (23%)
Similarity:	195/469 - (41%)	Gaps:	112/469 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 SPE--HTRDFAEVDI---NNGAATGSEDEEEEVPAPGSVTLDRNESDLFVSALSPSSIGDIHPLQ 64
            ||:  ..|.|.:.|:   |.|...|:..     ||..|..|:|.:.|           .||
  Rat    40 SPDLLMARSFGDKDLILPNGGTPAGTSS-----PASSSSLLNRLQLD-----------DDI---- 84

  Fly    65 EVLTDDG---DYFISIVVSDPQKIGDGMGSYLAYKVTTKTNIPKFKRSEFSTLRRFSDFLGIHDL 126
                 ||   |.|::  |.||:|....|.:|:.|::|||:...:|...|:|..||:.||..:.:.
  Rat    85 -----DGETRDLFVT--VDDPKKHVCTMETYITYRITTKSTRVEFDLPEYSVRRRYQDFDWLRNK 142

  Fly   127 LVGKYMRLGRIIPPAPSKNIIGSTKVKISPQQSEPGTPMTQEWVEIRRAALERFVHRTAQHPVLR 191
            |  :..:...:|||.|.|.::.....:.|           :|:||.||.||::|:.|...||||.
  Rat   143 L--EESQPTHLIPPLPEKFVVKGVVDRFS-----------EEFVETRRKALDKFLKRITDHPVLS 194

  Fly   192 VDLDFMNFLESDQELPRSVNTSALSGAGVIRLFNKVGETVNKIT--YKMDEN-------DPWFDD 247
            .:..|..||.:     :.:|.....|   |.|..:|||:|..:|  ||:...       ..:.|.
  Rat   195 FNEHFNVFLTA-----KDLNAYKKQG---IALLTRVGESVKHVTGGYKLRSRPLEFAAIGDYLDT 251

  Fly   248 KITEVESLDANLQKLHNAMKSLVTSRREL-------SLLTGLVAKSAAMLSTCEEHTGLSRALSN 305
            ...::.::|...|::.......:...||.       |.|.|.:|:....:|.|..:  .|.||..
  Rat   252 FALKLGTIDRIAQRIIKEEIEYLVELREYGPVYSTWSALEGELAEPLEGVSACIGN--CSTALEE 314

  Fly   306 LAD--VEEKIELLRSEQANSDFFILAEFIKDYLGLFGAIKCIFHERVKAFQNWQYAQMQLSKRRE 368
            |.|  .||.:.:||                :|:....::|.:..:|.:....::.....::.|:|
  Rat   315 LTDDITEEFLPVLR----------------EYILYSDSMKGVLKKRDQVHAEYEAKLEAVALRKE 363

  Fly   369 NRGRFELANRADKLDQAQQEVDEWQGKVQRCQQQFDDISAEIKREMERFELTRVKDFKVNIIKYI 433
            :|.:..    ||               |::||.:.:..:|::|.:|||::..:..||: .::..:
  Rat   364 DRPKVP----AD---------------VEKCQDRMECFNADLKADMERWQGNKRNDFR-QLLVGL 408

  Fly   434 EDQMAHQQQIVSYW 447
            .|:.....:..|.|
  Rat   409 ADKNIQYYEKASAW 422

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Snx1	NP_608777.1	PX_SNX1_2_like	75..203	CDD:132769	40/127 (31%)
Snx1	NP_608777.1	BAR_SNX1_2	232..455	CDD:153307	44/234 (19%)
Snx30	XP_038965375.1	PX_SNX7_30_like	91..206	CDD:132770	41/134 (31%)
Snx30	XP_038965375.1	BAR	190..422	CDD:416402	58/277 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5391
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D947320at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820