Protein Alignment Snx1 and SNX32

DIOPT Version :10

• Sequence 1: NP_608777.1
• Gene: Snx1 / 33560
• FlyBaseID: FBgn0031534
• Length: 458
• Species: Drosophila melanogaster
• Sequence 2: NP_689973.2
• Gene: SNX32 / 254122
• HGNCID: 26423
• Length: 403
• Species: Homo sapiens
• Alignment Length: 386
• Identity: 95/386 - (24%)
• Similarity: 173/386 - (44%)
• Gaps: 40/386 - (10%)

  Fly    71 GDYFISIVVSDPQKIGDGMGSYLAYKVTTKTNIPKFKRSEFSTLRRFSDFLGIHDLLVGKYMRLG 135
            ||..:.:.:||.....|    .:.:.|.||:.:|.|.::|||.:|:..:|:.:||..|......|
Human    22 GDSSLQVEISDAVSERD----KVKFTVQTKSCLPHFAQTEFSVVRQHEEFIWLHDAYVENEEYAG 82

  Fly   136 RIIPPAPSKNIIGSTKVKISPQQSEPGTPMTQEWVEIRR--------------AALERFVHRTAQ 186
            .||||||.:....:::.|:........:...:|:.::::              |..|.|:.|.|.
Human    83 LIIPPAPPRPDFEASREKLQKLGEGDSSVTREEFAKMKQELEAEYLAIFKKTVAMHEVFLQRLAA 147

  Fly   187 HPVLRVDLDFMNFLESDQELP-RSVNTSALSGAGVIRLFNKVGETVNKITYKMDENDPWFDDKIT 250
            ||.||.|.:|..|||..|:|. |..|...|.|..:..:.....|.:......:.|.|.:|:.:.|
Human   148 HPTLRRDHNFFVFLEYGQDLSVRGKNRKELLGGFLRNIVKSADEALITGMSGLKEVDDFFEHERT 212

  Fly   251 EVESLDANLQKLHNAMKSLVTSRRELSLLTGLVAKSAAMLST-CEEHTGLSRALSNLADVEEKIE 314
            .:  |:.:.:.....:::....|....|....:..|||:.|. .:|...|..:...||::.|::.
Human   213 FL--LEYHTRIRDACLRADRVMRAHKCLADDYIPISAALSSLGTQEVNQLRTSFLKLAELFERLR 275

  Fly   315 LLRSEQANSDFFILAEFIKDYLGLFGAIKCIFHERVKAFQNWQYAQMQLSKRRENRGRFELANRA 379
            .|....|:.:...|::.::.|:....|.|.:.:.|::|..:                 :|.||:|
Human   276 KLEGRVASDEDLKLSDMLRYYMRDSQAAKDLLYRRLRALAD-----------------YENANKA 323

  Fly   380 -DKLDQAQQEVDEWQGKVQRCQQQFDDISAEIKREMERFELTRVKDFKVNIIKYIEDQMAH 439
             ||.....:||...:...|.|.|:|:.:|...|:|:..|:..||..|:.|:|:..|.::.|
Human   324 LDKARTRNREVRPAESHQQLCCQRFERLSDSAKQELMDFKSRRVSSFRKNLIELAELELKH 384

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Snx1	NP_608777.1	PX_SNX1_2_like	75..203	CDD:132769	39/141 (28%)
		BAR_SNX1_2	232..455	CDD:153307	47/210 (22%)
SNX32	NP_689973.2	PX_domain	25..163	CDD:470617	38/141 (27%)
		BAR_SNX5_6	180..400	CDD:153305	48/224 (21%)