Protein Alignment Snx1 and snx2

DIOPT Version :10

• Sequence 1: NP_608777.1
• Gene: Snx1 / 33560
• FlyBaseID: FBgn0031534
• Length: 458
• Species: Drosophila melanogaster
• Sequence 2: XP_012823895.1
• Gene: snx2 / 100492702
• XenbaseID: XB-GENE-5791488
• Length: 523
• Species: Xenopus tropicalis
• Alignment Length: 491
• Identity: 229/491 - (46%)
• Similarity: 319/491 - (64%)
• Gaps: 47/491 - (9%)

  Fly     5 SPEHTRDFAEVDI---NNGAATGSE---DEEEEV--PAPGSVTLDRNESDLFVSA--------LS 53
            |||.....|| ||   :||..|...   |:.|::  .|...|:||..|.||.:|:        ::
 Frog    41 SPEPASLPAE-DISTNSNGPKTTEVLLCDDREDLFAEATDEVSLDSPERDLILSSEPSPAITPVT 104

  Fly    54 PSSIGDIHPLQEVL-----------TDD------GDYF-ISIVVSDPQKIGDGMGSYLAYKVTTK 100
            |:|:  |.|..|.:           ||:      ||.| :.|.||||:|:||||.:|:|||||||
 Frog   105 PTSL--IMPRMETISISAPVIYDRSTDEIEEEANGDAFDVEIGVSDPEKVGDGMNAYMAYKVTTK 167

  Fly   101 TNIPKFKRSEFSTLRRFSDFLGIHDLLVGKYMRLGRIIPPAPSKNIIGSTKVKISPQQSEPGTPM 165
            |::..|.::|||..||||||||:|..|..|||.:|.|:||||.|:|:|.||||:..:.|.
 Frog   168 TSLSMFNKNEFSVRRRFSDFLGLHSKLATKYMHIGYIVPPAPEKSIVGMTKVKVGKEDSS----- 227

  Fly   166 TQEWVEIRRAALERFVHRTAQHPVLRVDLDFMNFLESDQELPRSVNTSALSGAGVIRLFNKVGET 230
            :.|:||.|||||||::.||.:||.|..|.|...|||| .||||:|:|.||||||::|:.||..:.
 Frog   228 SNEFVEKRRAALERYLQRTVKHPTLLQDPDLRQFLES-SELPRAVSTQALSGAGLLRMVNKAADA 291

  Fly   231 VNKITYKMDENDPWFDDKITEVESLDANLQKLHNAMKSLVTSRRELSLLTGLVAKSAAMLSTCEE 295
            |||:|.||:|:|.||::|..:.|:||..|:|||..::|||..|:|||..|...|||||||...|:
 Frog   292 VNKMTIKMNESDAWFEEKQQQFENLDQQLRKLHGNVESLVCHRKELSANTAAFAKSAAMLGNSED 356

  Fly   296 HTGLSRALSNLADVEEKIELLRSEQANSDFFILAEFIKDYLGLFGAIKCIFHERVKAFQNWQYAQ 360
            ||.||||||.||:|||||:.|..:||.:||::..|.:.||:.|..|:|.:|.:|:|.:|.||.||
 Frog   357 HTALSRALSQLAEVEEKIDQLHQDQAFADFYLFTELLSDYIRLIAAVKGVFDQRMKCWQKWQDAQ 421

  Fly   361 MQLSKRRENRGRFELANRADKLDQA----QQEVDEWQGKVQRCQQQFDDISAEIKREMERFELTR 421
            :.|.|::|...:.:::|:.|||.||    ::|::||:.|||:.::.||.||..|::|:.|||..|
 Frog   422 VNLQKKQEAEAKLQISNKPDKLQQAKDEIREEIEEWEAKVQQGERDFDQISKTIRKEVGRFEKER 486

  Fly   422 VKDFKVNIIKYIEDQMAHQQQIVSYWEAFAPFAREI 457
            |:|||..||||:|..:..|||::.|||||.|.|:.|
 Frog   487 VRDFKSVIIKYLESLVRTQQQLIKYWEAFLPEAKAI 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Snx1	NP_608777.1	PX_SNX1_2_like	75..203	CDD:132769	70/127 (55%)
		BAR_SNX1_2	232..455	CDD:153307	110/226 (49%)
snx2	XP_012823895.1	Sorting_nexin	3..75	CDD:461016	12/34 (35%)
		PX_SNX2	142..265	CDD:132815	71/128 (55%)
		BAR	283..520	CDD:472257	114/236 (48%)