DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Snx1 and snx1

DIOPT Version :9

Sequence 1:	NP_608777.1	Gene:	Snx1 / 33560	FlyBaseID:	FBgn0031534	Length:	458	Species:	Drosophila melanogaster
Sequence 2:	XP_002938918.2	Gene:	snx1 / 100145678	XenbaseID:	XB-GENE-992259	Length:	509	Species:	Xenopus tropicalis

Alignment Length:	485	Identity:	207/485 - (42%)
Similarity:	300/485 - (61%)	Gaps:	49/485 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 DINNGA---ATGSEDEEEEVPAPGS----VTLDRNESDLFVSALSPSSIGDIHPLQ--------- 64
            ||..||   .|..:.::|.||...|    :.|:.::.|||..:....|:.:.|.:|
Frog    30 DIFTGAHSEVTAPKTKKETVPDQPSRENGLFLEDDDQDLFAESTVKLSVDNSHNMQTEEPPKVSL 94

  Fly    65 ---------------------------EVLTDDGDYFISIVVSDPQKIGDGMGSYLAYKVTTKTN 102
                                       |....:..:.:.|.|:||:||||||.:|:.|:|||:||
Frog    95 TTSMLIEAASASAKPKQKSYEELEEEEEEQEQEDQFDVKISVTDPEKIGDGMNAYVVYRVTTQTN 159

  Fly   103 IPKFKRSEFSTLRRFSDFLGIHDLLVGKYMRLGRIIPPAPSKNIIGSTKVKISPQQSEPGTPMTQ 167
            :..||...|:..||||||||:::.|..|:.:.|.||.|.|.|::||.||||:..:.|.     :.
Frog   160 LLMFKSKHFTVKRRFSDFLGLYEKLSEKHSQNGFIIAPPPEKSLIGMTKVKVGKEDSS-----SA 219

  Fly   168 EWVEIRRAALERFVHRTAQHPVLRVDLDFMNFLESDQELPRSVNTSALSGAGVIRLFNKVGETVN 232
            |::|.|||||||::.|...||.|..|.|..:|||.| ||||:|:|.||||||::::||:..:.||
Frog   220 EFLERRRAALERYLQRIVSHPTLLQDPDVRDFLEKD-ELPRAVSTQALSGAGLLKMFNRATDAVN 283

  Fly   233 KITYKMDENDPWFDDKITEVESLDANLQKLHNAMKSLVTSRRELSLLTGLVAKSAAMLSTCEEHT 297
            |:|.||:|:|.||:||..|||..:.:|:|||..:::||..|:||:|.|.|.|||.|||.:.|::|
Frog   284 KMTIKMNESDAWFEDKFQEVECEEQHLRKLHTVVETLVNHRKELALNTALFAKSLAMLGSSEDNT 348

  Fly   298 GLSRALSNLADVEEKIELLRSEQANSDFFILAEFIKDYLGLFGAIKCIFHERVKAFQNWQYAQMQ 362
            .||||||.||:||||||.|..||||||||:|||.:.||:.:..|::.:|.:|:|.:|.||.||..
Frog   349 ALSRALSQLAEVEEKIEQLHQEQANSDFFLLAELLADYIRMLSAVRGVFDQRMKTWQRWQDAQAI 413

  Fly   363 LSKRRENRGRFELANRADKLDQAQQEVDEWQGKVQRCQQQFDDISAEIKREMERFELTRVKDFKV 427
            |.|:|||..|...||:.|||.||:.|:.||:.:|.:.::.|:.||..:::|:.|||..:.||||.
Frog   414 LQKKRENEARLLWANKPDKLQQAKDEITEWESRVTQYERDFERISVTVRKEVTRFEKEKSKDFKS 478

  Fly   428 NIIKYIEDQMAHQQQIVSYWEAFAPFAREI 457
            :|:||:|..:..|.::|.|||||.|.|:.|
Frog   479 HIVKYLETLLNSQHKLVKYWEAFLPEAKVI 508

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Snx1	NP_608777.1	PX_SNX1_2_like	75..203	CDD:132769	61/127 (48%)
Snx1	NP_608777.1	BAR_SNX1_2	232..455	CDD:153307	111/222 (50%)
snx1	XP_002938918.2	Sorting_nexin	9..70	CDD:397658	12/39 (31%)
		PX_SNX1	132..255	CDD:132814	61/127 (48%)
		BAR_SNX1	273..506	CDD:153349	114/232 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	146	1.000	Domainoid score	I4512
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	339	1.000	Inparanoid score	I2319
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D299625at33208
OrthoFinder	1	1.000	-	-		FOG0001310
OrthoInspector	1	1.000	-	-		otm49449
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1340
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	7.060