| Sequence 1: | NP_000612.1 | Gene: | HTR2A / 3356 | HGNCID: | 5293 | Length: | 471 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_012467.1 | Gene: | YJL068C / 853377 | SGDID: | S000003604 | Length: | 299 | Species: | Saccharomyces cerevisiae |
| Alignment Length: | 7 | Identity: | 5/7 - (71%) |
|---|---|---|---|
| Similarity: | 6/7 - (85%) | Gaps: | 0/7 - (0%) |
- Green bases have known domain annotations that are detailed below.
|
Human 240 FVSFFIP 246 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| HTR2A | NP_000612.1 | 7tmA_5-HT2A | 75..391 | CDD:341345 | 5/7 (71%) |
| TM helix 1 | 76..102 | CDD:341345 | |||
| TM helix 2 | 109..135 | CDD:341345 | |||
| TM helix 3 | 148..178 | CDD:341345 | |||
| DRY motif, important for ligand-induced conformation changes. /evidence=ECO:0000250|UniProtKB:P41595 | 172..174 | ||||
| TM helix 4 | 190..213 | CDD:341345 | |||
| TM helix 5 | 231..260 | CDD:341345 | 5/7 (71%) | ||
| TM helix 6 | 316..346 | CDD:341345 | |||
| TM helix 7 | 359..384 | CDD:341345 | |||
| NPxxY motif, important for ligand-induced conformation changes and signaling. /evidence=ECO:0000250|UniProtKB:P41595 | 376..380 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 451..471 | ||||
| PDZ-binding. /evidence=ECO:0000269|PubMed:11150294, ECO:0000269|PubMed:14988405 | 469..471 | ||||
| YJL068C | NP_012467.1 | alpha/beta hydrolases | 2..296 | CDD:473884 | 5/7 (71%) |
| Blue background indicates that the domain is not in the aligned region. | |||||