DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2772 and TGL1

DIOPT Version :9

Sequence 1:	NP_608776.1	Gene:	CG2772 / 33559	FlyBaseID:	FBgn0031533	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	NP_012782.1	Gene:	TGL1 / 853717	SGDID:	S000001623	Length:	548	Species:	Saccharomyces cerevisiae

Alignment Length:	398	Identity:	105/398 - (26%)
Similarity:	163/398 - (40%)	Gaps:	40/398 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 DPFIDIPFKRLKTSAERIAEHGYPAESHFVETPDGYVLNVFRIPHSPKLNSNGNEGESEASRPVV 86
            |..|:...:...|..|..|......|.|.|.|.|.|:|.:.|||...|...|..         ||
Yeast    53 DNTIEEKLRSAPTIHEMCAIFDISVEDHLVRTEDNYILTLHRIPPISKNRFNNK---------VV 108

  Fly    87 LIMHGLFSCSDCFLLN-GPEDALPYNYADAGYDVWLGNARGNIYSRNNTRLNVKHPYFWKFSWHE 150
            .:.|||..|||.:..| .....||:...|.|||||:||.|||.||..:.....|...||.||..|
Yeast   109 YLHHGLLMCSDVWCCNIERHKNLPFVLHDLGYDVWMGNNRGNKYSTAHLNKPPKSNKFWDFSIDE 173

  Fly   151 IGSIDLPATIDYILAETGQQSLHYVGHSQGCTSFFVMGSYRPEYNAKIKTAHMLAP---PVYMGN 212
            ....|:|.:|::||..|....:..:|.|||....|...|...:.|.|:.....:||   |..:.|
Yeast   174 FAFFDIPNSIEFILDITKVDKVICIGFSQGSAQMFAAFSLSEKLNRKVSHFIAIAPAMTPKGLHN 238

  Fly   213 STEGLIVSTAPLFGHHGIGSTLLENQVLLPQNAFIQRVLDTTCSNQPIMLSYCKTLA--ILWGGP 275
            .....:..::|.|.:...|     .:::||.....||.|      .|.:.:.|..:|  ||:...
Yeast   239 RIVDTLAKSSPGFMYLFFG-----RKIVLPSAVIWQRTL------HPTLFNLCIDIANKILFNWK 292

  Fly   276 EIGNLNQTLLPQIAETHPAGVSSNQAIHYIQSYASNDFRLYDWGSKRNL-----EYYGVSEPPAY 335
            ....|.:..:...|:.: :..|....:|:.|...|..|::::  ...|:     ..|.::..|.
Yeast   293 SFNILPRQKIASYAKLY-STTSVKSIVHWFQILRSQKFQMFE--ESDNMLNSLTRPYQIANFPT- 353

  Fly   336 DLTKITSELYLYYGLADGSANKQDISRLPDLLPNLALLHEVPDSTWGHLDFIFATEVKRVINDLV 400
             .|.|...:.|.||   |..:..||..:...|| ...:.:|....:.|||.|:..:...::...|
Yeast   354 -RTNIKIPILLIYG---GIDSLVDIDVMKKNLP-FNSVFDVKVDNYEHLDLIWGKDADTLVIAKV 413

  Fly   401 LDYSKAYD 408
            |.:.:.::
Yeast   414 LRFIEFFN 421

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2772	NP_608776.1	PLN02872	5..393	CDD:215470	103/381 (27%)
		Abhydro_lipase	36..103	CDD:282003	23/67 (34%)
		Abhydrolase	113..>196	CDD:304388	31/82 (38%)
TGL1	NP_012782.1	Abhydro_lipase	66..124	CDD:397965	22/66 (33%)
TGL1	NP_012782.1	Abhydrolase_1	106..402	CDD:395444	86/324 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	108	1.000	Domainoid score	I1418
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	139	1.000	Inparanoid score	I1188
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55134
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		otm46497
orthoMCL	1	0.900	-	-		OOG6_100408
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
TreeFam	0	0.000	Not matched by this tool.
	10	9.770