DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2772 and Lipo4

DIOPT Version :9

Sequence 1:	NP_608776.1	Gene:	CG2772 / 33559	FlyBaseID:	FBgn0031533	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	NP_001310315.1	Gene:	Lipo4 / 628236	MGIID:	3779637	Length:	398	Species:	Mus musculus

Alignment Length:	383	Identity:	120/383 - (31%)
Similarity:	201/383 - (52%)	Gaps:	29/383 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 SAERIAEH-GYPAESHFVETPDGYVLNVFRIPHSPKLNSNGNEGESEASRPVVLIMHGLFSCSDC 98
            :..:|.:| .||:|.:.|.|.|||:|.:.||||. |.|:|     |.|.:.||...|||.:....
Mouse    32 NVSQIIKHWEYPSEEYEVVTDDGYILPINRIPHG-KNNAN-----SSAPKMVVFCQHGLLATPGA 90

  Fly    99 FLLNGPEDALPYNYADAGYDVWLGNARGNIYSRNNTRLNVKHPYFWKFSWHEIGSIDLPATIDYI 163
            ::.|.|:::|.:..||||||||:|::||:.:::.:..||.....||.||:.::...||||||::|
Mouse    91 WVSNLPDNSLAFILADAGYDVWMGSSRGSTWAKKHVTLNTDSKEFWDFSFDQMIKYDLPATINFI 155

  Fly   164 LAETGQQSLHYVGHSQGCTSFFVMGSY--RPEYNAKIKTAHMLAPPVYMGNSTEGLIVSTAPLFG 226
            |.:|||:.::|:|||||  :...:|::  ..:...|||...:|| |:|....::|:...|:.|
Mouse   156 LDKTGQKQIYYIGHSQG--TLIAIGAFATNQKLAEKIKLNILLA-PIYSVQHSKGIARLTSYL-- 215

  Fly   227 HHGIGSTLLENQVLLPQNAFIQRVLDT-----TCSNQPIMLSYCKTLAILWGGPEIGNLNQTLLP 286
                  |....:||..:..|:..|:.:     .|... ::.:.|..:....||.....||.:.|.
Mouse   216 ------TPTTIKVLFGEKEFLPTVVSSEVGAYVCDIN-LVTAGCAAMIGSMGGYSPEQLNMSRLD 273

  Fly   287 QIAETHPAGVSSNQAIHYIQSYASNDFRLYDWGSKR-NLEYYGVSEPPAYDLTKITSELYLYYGL 350
            ...:.:.||.|....|||.|...|...:.|||||.. |:::|..:.||.|::..:.....::.||
Mouse   274 VYVKLNLAGTSVKILIHYNQIRRSGILQAYDWGSSSLNMQHYNQTTPPVYNVEDMKVPTAMFTGL 338

  Fly   351 ADGSANKQDISRLPDLLPNLALLHEVPDSTWGHLDFIFATEVKRVINDLVLDYSKAYD 408
            .|..::.:|:..|...:.||..|..:||  :.|.|||:....:..:::.:|...:.||
Mouse   339 KDFLSDPEDVEILKPKIHNLTYLKTIPD--FSHFDFIWGLNAREEVSEEILTILRKYD 394

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2772	NP_608776.1	PLN02872	5..393	CDD:215470	117/366 (32%)
		Abhydro_lipase	36..103	CDD:282003	25/67 (37%)
		Abhydrolase	113..>196	CDD:304388	35/84 (42%)
Lipo4	NP_001310315.1	Abhydro_lipase	33..95	CDD:282003	25/67 (37%)
Lipo4	NP_001310315.1	Abhydrolase_1	77..375	CDD:278959	97/311 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831758
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100408
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.860