DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2772 and lipa

DIOPT Version :9

Sequence 1:	NP_608776.1	Gene:	CG2772 / 33559	FlyBaseID:	FBgn0031533	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	NP_001015847.2	Gene:	lipa / 548564	XenbaseID:	XB-GENE-952977	Length:	409	Species:	Xenopus tropicalis

Alignment Length:	408	Identity:	132/408 - (32%)
Similarity:	205/408 - (50%)	Gaps:	26/408 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 VLTILAIVASAGAADDFDPFI------DIPFKRLKTSAERIAE----HGYPAESHFVETPDGYVL 59
            ::.:.|::.:....||....|      |:.:.....:...|:|    .|||:|.:.|.|.|||:|
Frog     9 LVAVTALIPAVALTDDVPSRIRHGVAGDLLYSADPEATMNISELIRYRGYPSEEYEVLTEDGYIL 73

  Fly    60 NVFRIPHSPKLNSNGNEGESEASRPVVLIMHGLFSCSDCFLLNGPEDALPYNYADAGYDVWLGNA 124
            :|.||||..|.       .||..:|||.:.|||.:....::.|...::|.:..||||||||:||:
Frog    74 SVNRIPHGVKY-------ASEGPKPVVFLQHGLLADGSNWVTNLENNSLGFILADAGYDVWIGNS 131

  Fly   125 RGNIYSRNNTRLNVKHPYFWKFSWHEIGSIDLPATIDYILAETGQQSLHYVGHSQGCTSFFVMGS 189
            |||.:||.:..|:.....||.||:.|:...||||.:|:|..:|||:.:.|||||||.|..|:..|
Frog   132 RGNTWSRKHKSLSPDQEEFWAFSYDELAKKDLPAVVDFITKKTGQEQIFYVGHSQGTTIAFIAFS 196

  Fly   190 YRPEYNAKIKTAHMLAPPVYMGNSTEGLI-VSTAPLFGHHGIGSTLLENQVLLPQNAFIQRVLDT 253
            ..|:...|||....|||...:..|...|. :...|.|    :...|......|||...|..:...
Frog   197 SLPQLAKKIKMYFGLAPVATVKFSKSPLAKLGVLPEF----LIEELFGKGEFLPQTYLITWLATH 257

  Fly   254 TCSNQPIMLSYCKTLAILWGGPEIGNLNQTLLPQIAETHPAGVSSNQAIHYIQSYASNDFRLYDW 318
            .|:: .|....|..:..|..|....|||.:.:...:...|||.|....:|:.|...|.:.:.:|:
Frog   258 FCTH-AIADELCGNIFFLLSGFNEKNLNMSRVNVYSSHCPAGTSVQNMLHWRQGVRSGELKAFDF 321

  Fly   319 GSKRNLEYYGVSEPPAYDLTKITSELYLYYGLADGSANKQDISRLPDLLPNLALLHEVPDSTWGH 383
            |:|.|:.:|..:.||.|.:..:|....|:.|..|..|:::|::.|...:.||....|:||  |.|
Frog   322 GTKGNMIHYNQTTPPFYHVRDMTVPTALWTGGNDWLADRKDVALLLTQVSNLVYHKEIPD--WEH 384

  Fly   384 LDFIFATEV-KRVINDLV 400
            ||||:..:. :|:.|:::
Frog   385 LDFIWGLDAPERMYNEII 402

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2772	NP_608776.1	PLN02872	5..393	CDD:215470	130/399 (33%)
		Abhydro_lipase	36..103	CDD:282003	26/70 (37%)
		Abhydrolase	113..>196	CDD:304388	41/82 (50%)
lipa	NP_001015847.2	Abhydro_lipase	49..110	CDD:282003	26/67 (39%)
		PLN02872	50..409	CDD:215470	126/367 (34%)
		Abhydrolase_5	91..>229	CDD:289465	57/137 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.030