DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2772 and Lipf

DIOPT Version :9

Sequence 1:	NP_608776.1	Gene:	CG2772 / 33559	FlyBaseID:	FBgn0031533	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	NP_059037.1	Gene:	Lipf / 50682	RGDID:	708441	Length:	395	Species:	Rattus norvegicus

Alignment Length:	416	Identity:	138/416 - (33%)
Similarity:	211/416 - (50%)	Gaps:	49/416 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 VLTILAIVASAGAADDFDPFIDIPFKRL--------KTSAERIAEHGYPAESHFVETPDGYVLNV 61
            :|.|.:::::.|.|...       |.:|        ...::.|...|||.:.:.|.|.|||:|.|
  Rat     3 LLLITSVISTFGGAHGL-------FGKLGPGNPEANMNISQMITYWGYPCQEYEVVTEDGYILGV 60

  Fly    62 FRIPHSPKLNSNGNEGESEASRPVVLIMHGLFSCSDCFLLNGPEDALPYNYADAGYDVWLGNARG 126
            :||||..      |..|:...||||.:.|||.:.:..::.|.|.::|.:..|||||||||||:||
  Rat    61 YRIPHGK------NNSENIGKRPVVYLQHGLIASATNWIANLPNNSLAFMLADAGYDVWLGNSRG 119

  Fly   127 NIYSRNNTRLNVKHPYFWKFSWHEIGSIDLPATIDYILAETGQQSLHYVGHSQGCTSFFVMGSYR 191
            |.:||.|...:.....||.||:.|:...||||||::|:.:|||:.:||||||||.|..|:..|..
  Rat   120 NTWSRKNVYYSPDSVEFWAFSFDEMAKYDLPATINFIVQKTGQEKIHYVGHSQGTTIGFIAFSTN 184

  Fly   192 PEYNAKIKTAHMLAPPVYMGNSTEGL-IVSTAPLFGHHGIGSTLLENQVLLPQNAF--------- 246
            |....||||.:.|||...:..:...| .:|..|.|    :...:...::.||...|
  Rat   185 PTLAKKIKTFYALAPVATVKYTQSPLKKISFIPTF----LFKLMFGKKMFLPHTYFDDFLGTEVC 245

  Fly   247 IQRVLDTTCSNQPIMLSYCKTLAILWGGPEIGNLNQTLLPQIAETHPAGVSSNQAIHYIQSYASN 311
            .:.|||..|||  .:..:|        |.:..|||.:........:|||.|....:|:.|...|.
  Rat   246 SREVLDLLCSN--TLFIFC--------GFDKKNLNVSRFDVYLGHNPAGTSVQDFLHWAQLVRSG 300

  Fly   312 DFRLYDWGS-KRNLEYYGVSEPPAYDLTKITSELYLYYGLADGSANKQDISRLPDLLPNLALLHE 375
            .|:.::||| .:|:.:|....||.||::.:|..:.::.|..|..|:.||::.|...|.||....|
  Rat   301 KFQAFNWGSPSQNMLHYNQKTPPEYDVSAMTVPVAVWNGGNDILADPQDVAMLLPKLSNLLFHKE 365

  Fly   376 VPDSTWGHLDFIFATEV-KRVINDLV 400
            :  ..:.|||||:|.:. :.|.|:::
  Rat   366 I--LAYNHLDFIWAMDAPQEVYNEMI 389

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2772	NP_608776.1	PLN02872	5..393	CDD:215470	136/407 (33%)
		Abhydro_lipase	36..103	CDD:282003	24/66 (36%)
		Abhydrolase	113..>196	CDD:304388	44/82 (54%)
Lipf	NP_059037.1	PLN02872	4..389	CDD:215470	138/413 (33%)
		Abhydro_lipase	34..96	CDD:282003	24/67 (36%)
		Abhydrolase_5	77..>221	CDD:289465	64/147 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335430
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	272	1.000	Inparanoid score	I2916
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100408
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.810