DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2772 and Lip2

DIOPT Version :9

Sequence 1:	NP_608776.1	Gene:	CG2772 / 33559	FlyBaseID:	FBgn0031533	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	NP_524667.1	Gene:	Lip2 / 43980	FlyBaseID:	FBgn0024740	Length:	413	Species:	Drosophila melanogaster

Alignment Length:	430	Identity:	113/430 - (26%)
Similarity:	190/430 - (44%)	Gaps:	57/430 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LTILAIVASAGAADDFDPFIDIPFKRLK-TSAERIAEHGYPAESHFVETPDGYVLNVFRIPHSPK 69
            :.::.||.:.|......|    |..|.| |:.:.:.......|.|.|.|.|||.|.:.|:|..
  Fly    10 IKVMLIVCAIGRNAHSSP----PESRYKWTTMDWLEAQNVSHEVHNVTTADGYQLQLQRLPRL-- 68

  Fly    70 LNSNGNEGESEASRPVVLIMHGLFSCSDCFLLNGPEDALPYNYADAGYDVWLGNARG-NIYSRNN 133
                       .::||:|: |||...|..::..|||.:|.:......|||||.|.|| :.|.|.:
  Fly    69 -----------GAKPVLLV-HGLLGSSLGWVCMGPERSLAFQLHHREYDVWLANLRGVSPYGRQH 121

  Fly   134 TRLNVKHPYFWKFSWHEIGSIDLPATIDYILAETG-------------QQSLHY----VGHSQGC 181
            ..|......||:||:||.|:.||||.||::...||             ::.:|:    :||||..
  Fly   122 IDLTDVMVEFWRFSFHEHGAYDLPAIIDHMAKVTGGEQLASRGGPGQDEEQIHHQVVLIGHSQAF 186

  Fly   182 TSFFVMGSYRPEYNAKIKTAHMLAPPVYMGNSTEGLIVSTAPLFGHHGIGSTLLENQVLLPQNAF 246
            .:|.|:.:..|.:|.:|:....|||...:.....      ...|....:...:.:.|.......|
  Fly   187 NAFLVLCAVHPRFNQRIQLIQALAPLARLHRQVR------FDSFQVRRLMKFIKKRQKAYKFEIF 245

  Fly   247 IQRVLDTTC-SNQPIMLSYCKTLAILWGGPEIGNL--NQTLLPQI-AETHPAGVSSNQAIHYIQS 307
            ........| :.:.:...|.|.|        :|:.  |:.||... .|....|.|..:..|..|.
  Fly   246 PPGYFRKVCQAKRDLCEYYAKQL--------VGSAQNNKKLLEAFNYEYLLQGGSPREIKHLQQI 302

  Fly   308 YASNDFRLYDWGSKRNLEYYGVSEPPAYDLTKITSELYLYYGLADGSANKQDISRL-PDLLPNLA 371
            :.|.||..||:|:..||:.|...|..:|::::||..:.||:|..|..|..:.:..: ..:|.::.
  Fly   303 WKSGDFISYDFGTAENLQVYHSVEALSYNISQITVPIILYFGETDAIATPEGVHAIYARMLRSVK 367

  Fly   372 LLHEVPDSTWGHLDFIFATEVKRVINDLVLDY-SKAYDAR 410
            .:..:....:.||||:.:.:||.::||.:::: .:.:|.|
  Fly   368 SVRRINSKKFNHLDFLISGDVKSLVNDKLIEHMEQFFDGR 407

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2772	NP_608776.1	PLN02872	5..393	CDD:215470	107/410 (26%)
		Abhydro_lipase	36..103	CDD:282003	17/66 (26%)
		Abhydrolase	113..>196	CDD:304388	34/100 (34%)
Lip2	NP_524667.1	PLN02872	24..407	CDD:215470	109/414 (26%)
Lip2	NP_524667.1	Abhydro_lipase	48..90	CDD:282003	17/55 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45439498
Domainoid	1	1.000	108	1.000	Domainoid score	I1418
eggNOG	1	0.900	-	-		E2759_KOG2624
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D39202at50557
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		otm46497
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
	9	8.850