DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2772 and CG11406

DIOPT Version :9

Sequence 1:	NP_608776.1	Gene:	CG2772 / 33559	FlyBaseID:	FBgn0031533	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	NP_001014548.1	Gene:	CG11406 / 37877	FlyBaseID:	FBgn0034990	Length:	396	Species:	Drosophila melanogaster

Alignment Length:	404	Identity:	134/404 - (33%)
Similarity:	212/404 - (52%)	Gaps:	27/404 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 AADDFDPFIDIPFKRLKTSAERIAE----HGYPAESHFVETPDGYVLNVFRIPHSPKLNSNGNEG 77
            |.::.:|..::....|.|.::.:.:    .....:.|.:||.|||.|::.||| :|:     |..
  Fly     2 APEEEEPEEEVARDSLCTRSDSVCQAVQRQQLQCQVHRIETADGYRLSLHRIP-APQ-----NRW 60

  Fly    78 ESEASRPVVLIMHGLFSCSDCFLLNGPEDALPYNYADAGYDVWLGNARGNIYSRNNTRLNVKHPY 142
            ..:..|| .|:||||...:..|:..|...:|........:||||.||||..:||.:..|......
  Fly    61 CPQQLRP-FLLMHGLLGSAGDFVSGGRGRSLALELHARCFDVWLANARGTTHSRGHRTLQTSDAR 124

  Fly   143 FWKFSWHEIGSIDLPATIDYILAETGQQSLHYVGHSQGCTSFFVMGSYRPEYNAKIKTAHMLAPP 207
            ||:|||||||..||||.:||:||.|.::.|||||||||.|...|:.|.||||||:...|.:|||.
  Fly   125 FWRFSWHEIGIYDLPAIVDYVLARTNRRQLHYVGHSQGTTVLLVLLSQRPEYNARFANAALLAPV 189

  Fly   208 VYMGNSTEGLIVSTAP--LFGHHGIGSTLLENQV----LLPQNAFIQRVLDTTCSNQPIMLSYCK 266
            .::.:      :|:.|  |.......:|||.|::    |||.:|..|......|:......:.|.
  Fly   190 AFLQH------LSSPPLRLLASDSSMATLLLNKLGLHELLPASALTQVGGQFFCTASRPTYALCT 248

  Fly   267 TLAILWGGPEIGNLNQTLLPQIAETHPAGVSSNQAIHYIQSYASNDFRLYDWGSKR-NLEYYGVS 330
            ....::.|.....|::::||:|.||.|||:|..|..|:.|...|..|:.||:.|.| |...||.:
  Fly   249 LFTSVYVGFSDYPLDRSILPRILETTPAGISRGQLQHFGQLINSGKFQQYDYRSPRLNTLRYGRT 313

  Fly   331 EPPAYDLTKITSELYLYYGLADGSANKQDISRL-PDLLPNLALLHEVPDSTWGHLDFIFATEVKR 394
            .||:|.|..:..:|.:::|..|..::..|:.|| .:|..::..:::||.  :.|:||:||:...:
  Fly   314 TPPSYQLANVRLQLQIFHGSRDTLSSLADVQRLVRELRNSVTQMYQVPG--YNHIDFLFASSAPQ 376

  Fly   395 VINDLVLDYSKAYD 408
            |:...::..:...|
  Fly   377 VVFQRIIQQAWQLD 390

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2772	NP_608776.1	PLN02872	5..393	CDD:215470	132/387 (34%)
		Abhydro_lipase	36..103	CDD:282003	20/70 (29%)
		Abhydrolase	113..>196	CDD:304388	45/82 (55%)
CG11406	NP_001014548.1	Abhydro_lipase	28..85	CDD:282003	20/63 (32%)
		Abhydrolase_1	67..371	CDD:278959	113/312 (36%)
		Abhydrolase_5	67..>203	CDD:289465	62/142 (44%)
		Abhydrolase_5	<315..365	CDD:289465	13/51 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45439411
Domainoid	1	1.000	150	1.000	Domainoid score	I1414
eggNOG	1	0.900	-	-		E2759_KOG2624
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	194	1.000	Inparanoid score	I1354
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D39202at50557
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		mtm1092
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
	10	9.900