DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2772 and CG8093

DIOPT Version :9

Sequence 1:	NP_608776.1	Gene:	CG2772 / 33559	FlyBaseID:	FBgn0031533	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	NP_001286441.1	Gene:	CG8093 / 36686	FlyBaseID:	FBgn0033999	Length:	398	Species:	Drosophila melanogaster

Alignment Length:	402	Identity:	156/402 - (38%)
Similarity:	212/402 - (52%)	Gaps:	16/402 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 VLTILAIVASAGAADDFDPFIDIPFKRLKTSAERIAEHGYPAESHFVETPDGYVLNVFRIPHSPK 69
            |:.::|:..|.|.|:...  .|.......|:...:..|||..|.|.|:|.|||:|.:.|||:|
  Fly     3 VVQLIAVFLSLGLANALP--ADTGRASSVTTVTIVRGHGYEIEEHEVQTSDGYILTMHRIPYS-- 63

  Fly    70 LNSNGNEGESEASRPVVLIMHGLFSCSDCFLLNGPEDALPYNYADAGYDVWLGNARGNIYSRNNT 134
             .:.|.:|    .||||.:||||...|..::|.||...|.|..::||||||:||||||.||:.:.
  Fly    64 -KNTGYDG----PRPVVFLMHGLLCSSSDWVLAGPHSGLAYLLSEAGYDVWMGNARGNTYSKRHA 123

  Fly   135 RLNVKHPYFWKFSWHEIGSIDLPATIDYILAETGQQSLHYVGHSQGCTSFFVMGSYRPEYNAKIK 199
            ..:.....||.|.||:||..||||.:||:|..|....|.|||||||.|||||:.|..|.:.::|:
  Fly   124 SKSPLLQPFWNFEWHDIGIYDLPAMMDYVLYWTNVTQLTYVGHSQGTTSFFVLNSMIPRFKSRIR 188

  Fly   200 TAHMLAPPVYMGNSTEGLIVSTAPLFGHHGIGSTLLENQVLLPQNAFIQRVLDTTCSNQPIMLSY 264
            :||:|||..:|.:....|.....||.|.......|..:...||....:.......||::.|....
  Fly   189 SAHLLAPVAWMEHMESPLATVGGPLLGQPNAFVELFGSAEFLPNTQLMNLFGALLCSDEAISQFM 253

  Fly   265 CKTLAILWGGPEIGNLNQTLLPQIAETHPAGVSSNQAIHYIQSYASNDFRLYDWGSKRNLEYYGV 329
            |.....|.||.....:|:||||.|..|.|||.|.||..||:|.|.|..||.:|:||.||.:.|..
  Fly   254 CTNTLFLLGGWNSPYINETLLPDIMATTPAGCSVNQIFHYLQEYNSGYFRQFDYGSTRNKKEYSS 318

  Fly   330 SEPPAYDLTKITSELYLYYGLADGSANKQDISRLPDLLPNLAL--LHEVPDSTWGHLDFIFATEV 392
            ..||.||:..|....||||...|..|:..|:.||...:...||  .:.:|:..|.|:||::...:
  Fly   319 KTPPEYDVEGIDVPTYLYYSDNDYFASLIDVDRLRYTMNPSALKSAYRMPEEKWNHIDFLWGLNI 383

  Fly   393 K-----RVINDL 399
            |     |||||:
  Fly   384 KEILYDRVINDI 395

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2772	NP_608776.1	PLN02872	5..393	CDD:215470	150/389 (39%)
		Abhydro_lipase	36..103	CDD:282003	27/66 (41%)
		Abhydrolase	113..>196	CDD:304388	44/82 (54%)
CG8093	NP_001286441.1	PLN02872	9..392	CDD:215470	150/391 (38%)
		Abhydro_lipase	31..92	CDD:282003	27/67 (40%)
		Abhydrolase_5	74..>214	CDD:289465	65/139 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471687
Domainoid	1	1.000	150	1.000	Domainoid score	I1414
eggNOG	1	0.900	-	-		E2759_KOG2624
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	194	1.000	Inparanoid score	I1354
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D39202at50557
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		mtm1092
orthoMCL	1	0.900	-	-		OOG6_100408
Panther	1	1.100	-	-	P	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
	11	10.800