DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2772 and CG7329

DIOPT Version :9

Sequence 1:	NP_608776.1	Gene:	CG2772 / 33559	FlyBaseID:	FBgn0031533	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	NP_001260357.1	Gene:	CG7329 / 34457	FlyBaseID:	FBgn0032271	Length:	457	Species:	Drosophila melanogaster

Alignment Length:	414	Identity:	148/414 - (35%)
Similarity:	205/414 - (49%)	Gaps:	40/414 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 VLTILAIVASAGAA------DDFDPFIDIPFKRLKTSAERIAEHGYPAESHFVETPDGYVLNVFR 63
            :|.:|.|....|:.      ::..|...|....|.| .:.:.::.:|||:|.|.|.|.|:|.:.|
  Fly     7 ILVVLGIYTLDGSGVLGGFMENTYPASVIEDAHLNT-IQLLEKYKHPAETHQVTTDDKYILTLHR 70

  Fly    64 IPHSPKLNSNGNEGESEASRPVVLIMHGLFSCSDCFLLNGPEDALPYNYADAGYDVWLGNARGNI 128
            |..             ..::||:|: |||...|..:::.|||..|.|.....|||||:||.|||.
  Fly    71 IAR-------------PGAKPVLLV-HGLEDTSSTWIVMGPESGLGYFLYANGYDVWMGNVRGNR 121

  Fly   129 YSRNNTRLNVK-HPYFWKFSWHEIGSIDLPATIDYILAETGQQSLHYVGHSQGCTSFFVMGSYRP 192
            ||:.:.:||.. ...:|.|||||||..||||.||.:|.:||.|.|.|.|||||.||||||.|.||
  Fly   122 YSKGHVKLNPNTDKSYWSFSWHEIGMYDLPAMIDGVLQKTGYQKLSYFGHSQGTTSFFVMASSRP 186

  Fly   193 EYNAKIKTAHMLAPPVYMGNSTEGLIVSTAPLFGHHGIGSTLL-ENQVLLPQNAFIQRVLDTTCS 256
            ||||||.....|||..:|.:       ..|||.|...:|..:. :|..|.|.:    .|....|.
  Fly   187 EYNAKIHLMSALAPVAFMKH-------MKAPLMGIARMGMNMFGDNFELFPHS----EVFLNQCL 240

  Fly   257 NQPIMLSYCKTLAILWG--GPEIGNLNQTLLPQIAETHPAGVSSNQAIHYIQSYASNDFRLYDWG 319
            :...||..|  :...|.  |......|.|:.|.:....|.|.:..||:||:|...|:.|..||:.
  Fly   241 SSAAMLKTC--MRFYWQIVGKNREEQNMTMFPVVLGHLPGGCNIKQALHYLQMQKSDRFCQYDYE 303

  Fly   320 SKRNLEYYGVSEPPAYDLTKITSELYLYYGLADGSANKQDISRLPDLLPNLALLHEVPDSTWGHL 384
            ||.|...||.|.||.|.|.:|.:.:.||||..|..:..:|:.||..:|||:...|..  ..|.|:
  Fly   304 SKENQRLYGRSTPPDYRLERIKAPVALYYGSNDYLSAVEDVHRLAKVLPNVVENHLY--RKWNHM 366

  Fly   385 DFIFATEVKRVINDLVLDYSKAYD 408
            |.|:....:|.|...:|...:.::
  Fly   367 DMIWGISARRSIQPRILQVMQYWE 390

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2772	NP_608776.1	PLN02872	5..393	CDD:215470	145/397 (37%)
		Abhydro_lipase	36..103	CDD:282003	18/66 (27%)
		Abhydrolase	113..>196	CDD:304388	50/83 (60%)
CG7329	NP_001260357.1	Abhydro_lipase	42..96	CDD:282003	19/68 (28%)
		Abhydrolase	73..239	CDD:304388	79/190 (42%)
		Abhydrolase_1	77..371	CDD:278959	126/309 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45439495
Domainoid	1	1.000	150	1.000	Domainoid score	I1414
eggNOG	1	0.900	-	-		E2759_KOG2624
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	194	1.000	Inparanoid score	I1354
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D39202at50557
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		mtm1092
orthoMCL	1	0.900	-	-		OOG6_100408
Panther	1	1.100	-	-	P	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
	11	10.800